Cellular Integrative Immune Markers in Elite Athletes
Int J Sports Med DOI: 10.1055/a-1976-6069The integrative immune markers neutrophil-lymphocyte-ratio (NLR),
platelet-lymphocyte-ratio (PLR) and systemic immune inflammation
index (SII) are established markers in clinical patient care. Adoption
of these markers in elite athletics might prove beneficial for monitoring
training and health. Blood samples of 195 healthy national Olympic squad
athletes were collected before a graded bicycle-ergometric exercise test until
complete exhaustion. Measurements included white blood cells, lymphocytes and
platelets, allowing for the calculation of the integrative immune markers.
Correlations between athlete characteristics (sex, age, sporting discipline,
training experience, training volume) and integrative immune marker-values were
assessed. In a subgroup analysis a second blood sample was collected from 25
athletes at 1 minute after exercise test to assess its effect on the
immune marker levels.An inverse correlation between peak power output and SII-level (Pearson
correlation coefficient=−.270, p<.001) and NLR-level
(Pearson correlation coefficient=−.249, p<.001) was
found. Athletes with higher aerobic fitness had significantly lower values of
SII and PLR compared to athletes with lower aerobic fitness. An elevated SII
(p=.003) and a reduced PLR (p=.001) ...
Source: International Journal of Sports Medicine - Category: Sports Medicine Authors: Zacher, Jonas Wesemann, Fabian Joisten, Niklas Walzik, David Bloch, Wilhelm Predel, Georg Tags: Clinical Sciences Source Type: research