Comprehensive multi-attribute method workflow for biotherapeutic characterization and current good manufacturing practices testing

Nature Protocols, Published online: 16 December 2022; doi:10.1038/s41596-022-00785-5The multi-attribute method directly characterizes and monitors multiple product quality attributes of a biopharmaceutical product via proteolytic digestion of the sample followed by reversed-phase chromatographic separation and high-resolution liquid chromatography-mass spectrometry analysis.
Source: Nature Protocols - Category: Biomedical Science Authors: Source Type: research