Distribution of periodontopathic bacterial species between saliva and tonsils

AbstractPeriodontopathic bacteria cause an inflammatory disease localized in the periodontal tissue and are associated with various conditions in other body parts. The distribution of periodontopathic bacterial species in the tonsils is unknown, even though the tonsils are located close to the oral cavity, and inflammation of the tonsils causes various systemic diseases. We detected the major periodontopathic bacterial species residing in saliva and tonsil specimens from 25 subjects undergoing tonsillectomy. Nine of the ten major periodontopathic bacterial species were detected by polymerase chain reaction of tonsil specimens, among whichCampylobacter rectus was the most common (80.0%), followed byPorphyromonas gingivalis (36.0%). The other seven types of periodontopathic bacterial species were distributed with 0% to 25.0% abundance in the tonsil specimens.C. rectus had a high detection rate in tonsil specimens (>  75.0%), regardless of whether it was detected in the corresponding saliva specimens. However, the detection rate forP. gingivalis in tonsil specimens was significantly higher in subjects withP. gingivalis-positive saliva (77.8%) than in those withP. gingivalis-negative saliva (6.3%;P <  0.001). Furthermore, 75.0% ofP. gingivalis in tonsil specimens did not have the knownfimA gene that encodes the 41-kDa filamentous appendage protein FimA, which is expressed on the cell surface of the bacteria. Our results suggest that certain periodontopathic bacterial ...
Source: Odontology - Category: Dentistry Source Type: research