Hyperfunctioning Intrathyroidal Parathyroid: a Misleading Preoperative Diagnosis

We present three patients with primary hyperparathyroidism related to hyperfunctioning intrathyroidal parathyroid retrospectively selected among 732 cases from own Institutional parathyroid PET/CT registry from 2018 to 2022. Intrathyroidal parathyroids showed intense18F-fluorocholine uptake but a variable echographic pattern, inconstant99mTc-MIBI uptake, and atypic iodine-contrast enhancement. Although rare, the possibility of an intrathyroidal parathyroid should be considered when no hyperfunctioning gland is found on preoperative imaging and thorough bilateral neck exploration.
Source: Nuclear Medicine and Molecular Imaging - Category: Nuclear Medicine Source Type: research