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Lycopene and Chrysin through Mitigation of Neuroinflammation and Oxidative Stress Exerted Antidepressant Effects in Clonidine-Induced Depression-like Behavior in Rats
J Diet Suppl. 2021 Oct 11:1-20. doi: 10.1080/19390211.2021.1988797. Online ahead of print.ABSTRACTDepression is a severely debilitating psychiatric disorder that influences more than 15% of the population worldwide. It has been demonstrated that it is associated with a high risk of developing other diseases such as cardiovascular diseases, diabetes, stroke, epilepsy, and cancer. The current study examines the possibility of chrysin and lycopene having an antidepressant effect in a rat model of depression induced by clonidine, as well as the mechanisms underlying this effect, including the role of neuroinflammation and oxid...
Source: Journal of Dietary Supplements - October 11, 2021 Category: Nutrition Authors: Ekram Nemr Abd Al Haleem Hebatalla I Ahmed Reem N El-Naga Source Type: research

L-Carnitine and Potential Protective Effects Against  Ischemia-Reperfusion Injury in Noncardiac Organs: From Experimental Data to Potential Clinical Applications.
L-Carnitine and Potential Protective Effects Against Ischemia-Reperfusion Injury in Noncardiac Organs: From Experimental Data to Potential Clinical Applications. J Diet Suppl. 2017 Oct 20;:1-17 Authors: Moghaddas A, Dashti-Khavidaki S Abstract The mechanism of ischemia-reperfusion (I/R) injury is complex and multifactorial. In this condition, systemic event results in morbidity and mortality in several pathologies, including myocardial infarction, ischemic stroke, acute kidney injury, trauma, and circulatory arrest. Hypoxia over ischemia phase leads to energy imbalance and changes of cellular homeosta...
Source: Journal of Dietary Supplements - October 21, 2017 Category: Nutrition Tags: J Diet Suppl Source Type: research

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