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P-035 completion of the circle of willis is gender, age, and indication relative
Conclusion The incidence of complete cow is greater in women for all age groups and decreases with age in both genders. the most frequently absent vessel is pcom, either unilaterally or bilaterally. completion was significantly reduced in ischemic stroke and a subset of hemorrhagic stroke patients, suggesting that an incomplete cow is a risk factor for these indications. Disclosures O. Zaninovich: None. W. Ramey: None. C. Walter: None. T. Dumont: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Zaninovich, O., Ramey, W., Walter, C., Dumont, T. Tags: Oral Poster Abstracts Source Type: research

E-006 Extremes of body mass indices and thrombectomy outcomes: a new paradox in acute stroke treatment?
Conclusion Extremes of BMI were associated with better clinical outcomes with a "reverse U-shaped relationship" in patients with large vessel occlusions of the anterior circulation undergoing endovascular treatment, as the best clinical outcomes were observed in the UW and MO. This paradox differs from the previously described "obesity paradox," in which OW and mildly Ob typically have better outcomes than the NW, UW, and MO.1,2 The cause of and implications for these findings in acute stroke treatment is unclear. While these results may be secondary to patient selection bias, additional potential mechanisms include possib...
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Lavie, J., Bennett, G., Arndt, S., Albar, A., Wojcik, K., Milburn, J., Vidal, G. Tags: Electronic Poster Abstracts Source Type: research

E-033 The smoking-thrombolysis paradox in large vessel occlusion acute ischemic stroke after endovascular therapy
Conclusion In stroke patients treated with mechanical thrombectomy, smoking does not seem to be associated with outcomes regardless of stroke subtype or location. Disclosures J. Grossberg: None. M. Bouslama: None. L. Rebello: None. D. Haussen: None. M. Frankel: None. R. Nogueira: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Grossberg, J., Bouslama, M., Rebello, L., Haussen, D., Frankel, M., Nogueira, R. Tags: Electronic Poster Abstracts Source Type: research

E-035 Ct perfusion outcomes may lead to better clinical outcomes following endovascular therapy in large vessel occlusion stroke
Conclusion CTP-based selection is associated with a favorable shift in functional outcomes in patients undergoing stent-retriever thrombectomy. Future prospective studies are warranted. Disclosures J. Grossberg: None. M. Bouslama: None. D. Haussen: None. L. Rebello: None. M. Frankel: None. R. Nogueira: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Grossberg, J., Bouslama, M., Haussen, D., Rebello, L., Frankel, M., Nogueira, R. Tags: Electronic Poster Abstracts Source Type: research

E-038 Multiphase cta and collateral scores: experience of a single comprehensive stroke center
Conclusion Collateral scores of 4 and 5 have over 80% rate of inclusion for thrombectomy in the setting of a large vessel occlusion. Transfer of patients is correlated with statistically significant poorer collateral scores. Reference . Menon BK, d’Esterre CD, Qazi EM, et al. Multiphase CT Angiography: A New Tool for the Imaging Triage of Patients with Acute Ischemic Stroke. Radiology2015May; 275(2):510–20 Disclosures G. Bennett: None. S. Arndt: None. J. Lavie: None. A. Albar: None. G. Vidal: 3; C; Penumbra. J. Milburn: 3; C; Penumbra.
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Bennett, G., Arndt, S., Lavie, J., Albar, A., Vidal, G., Milburn, J. Tags: Electronic Poster Abstracts Source Type: research

E-041 Early recanalization rate after iv-tpa and treatment results of additional intra-arterial thrombolysis in large artery intracranial occlusion disease patients
Conclusion The recanalization rate after IV-tPA in LAICOD patients was low. Additional IA-Tx for non-recanalized patients after IV-tPA could improve the patient outcomes. And P/D-mismatch on acute stroke MR, which taken before the IA-Tx. was good indicator for the safety and effectiveness for additional IA-Tx. Disclosures Y. Won: None. D. Yoo: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Won, Y., Yoo, D. Tags: Electronic Poster Abstracts Source Type: research

E-045 Nihss and its component subscores are suboptimal predictors with colinearity
Conclusions NIHSS composite score is a suboptimal predictor for assessed patient outcomes. Principal component analysis improves predictive value of assessment with a statistically significant effect for pre-intervention patient outcomes analysis. Statistically significant variables are heavily dependent of NIHSS subscores, and variation in the distribution of these subscore may represent a significant source of bias. References . OA Berkhemer, et al. MR CLEAN, a multicenter randomized clinical trial of endovascular treatment for acute ischemic stroke in the Netherlands: new england journal of med 372;1 nejm.org january 1...
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Arndt, S., Albar, A., Bennett, G., Lavie, J., Gulotta, P., Milburn, J. Tags: Electronic Poster Abstracts Source Type: research

E-046 Length of stay in mechanical thrombectomy, and machine learning improvement of predictive analysis
Conclusions Machine learning methods outperform multivariate logistic regression at the prediction of length of stay. Predictive analysis for patient length of stay could help hospital utilization and allow for more aggressive measures to prevent hospital acquired conditions. Disclosures S. Arndt: None. G. Bennett: None. K. Wojcik: None. A. Albar: None. M. Alhasan: None. J. Ma: None. P. Gulotta: None. J. Milburn: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Arndt, S., Bennett, G., Wojcik, K., Albar, A., Alhasan, M., Ma, J., Gulotta, P., Milburn, J. Tags: Electronic Poster Abstracts Source Type: research

Primary acute stroke thrombectomy within 3 h for large artery occlusion (PAST3-LAO): a pilot study
Conclusions Our study demonstrates that primary SRT in AIS from LAO is safe and feasible and is associated with complete recanalization and good outcome. Further study is required.
Source: Journal of NeuroInterventional Surgery - March 15, 2017 Category: Neurosurgery Authors: Lodi, Y., Reddy, V., Petro, G., Devasenapathy, A., Hourani, A., Chou, C.-A. Tags: Ischemic stroke Source Type: research

Admission CT perfusion may overestimate initial infarct core: the ghost infarct core concept
Conclusions CT perfusion may overestimate final infarct core, especially in the early time window. Selecting patients for reperfusion therapies based on the CTP mismatch concept may deny treatment to patients who might still benefit from reperfusion.
Source: Journal of NeuroInterventional Surgery - December 13, 2016 Category: Neurosurgery Authors: Boned, S., Padroni, M., Rubiera, M., Tomasello, A., Coscojuela, P., Romero, N., Muchada, M., Rodriguez-Luna, D., Flores, A., Rodriguez, N., Juega, J., Pagola, J., Alvarez-Sabin, J., Molina, C. A., Ribo, M. Tags: Neuroimaging Source Type: research

Risk of acute kidney injury associated with neuroimaging obtained during triage and treatment of patients with acute ischemic stroke symptoms
Conclusions This study provides preliminary evidence of the safety and feasibility of obtaining CTSS with additional DSA imaging, whether for diagnosis or intervention, to identify possible acute ischemic stroke.
Source: Journal of NeuroInterventional Surgery - November 14, 2016 Category: Neurosurgery Authors: Hall, S. L., Munich, S. A., Cress, M. C., Rangel-Castilla, L., Levy, E. I., Snyder, K. V., Siddiqui, A. H. Tags: Ischemic stroke Source Type: research

In vitro experiments of cerebral blood flow during aspiration thrombectomy: potential effects on cerebral perfusion pressure and collateral flow
Conclusions These experiments suggest that aspiration is only effective if the catheter tip is in direct contact with the thrombus. If the catheter tip is not in contact with the thrombus, aspirate is drawn from the vessels proximal of the occlusion. This could affect collateral flow in vivo.
Source: Journal of NeuroInterventional Surgery - August 11, 2016 Category: Neurosurgery Authors: Lally, F., Soorani, M., Woo, T., Nayak, S., Jadun, C., Yang, Y., McCrudden, J., Naire, S., Grunwald, I., Roffe, C. Tags: Basic science Source Type: research

O-002 Presenting Diffusion-Restricted Core Volume, Not Time, Predicts Final Infarct Volume after Thrombectomy in Anterior Circulation Large Vessel Occlusion Stroke
ConclusionPresentation volume of diffusion-restricted core was a strong predictor of final infarct volume post-thrombectomy in this cohort of ACLVO patients, whereas time-based covariates showed little if any significant predictive value. For every 1 mL increase in presentation infarct volume, the odds of a small completed infarct were reduced by about 6%. A presentation core volume ≤50 mL improved the odds of a small final infarct by at least 26%, probably more.DisclosuresB. Cristiano: None. M. Pond: None. S. Basu: None. U. Oyoyo: None. J. Jacobson: 4; C; GeneLux.
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Cristiano, B., Pond, M., Basu, S., Oyoyo, U., Jacobson, J. Tags: Oral abstracts Source Type: research

O-007 Recanalization and Outcome Comparisons in Acute Ischemic Stroke Patients Treated with Mechanical Thrombectomy Selected by CT/MR Perfusion Imaging Versus CT Angiography
ConclusionsMechanical thrombectomy patients selected by CTA or perfusion imaging demonstrated no difference in successful recanalization rate, but higher level of recanalization/reperfusion and a trend of improved outcomes with CTA selection that may be attributed to improved treatment times.DisclosuresA. Honarmand: None. A. Shaibani: None. M. Hurley: None. P. Golnari: None. M. Potts: None. B. Jahromi: None. S. Ansari: None.
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Honarmand, A., Shaibani, A., Hurley, M., Golnari, P., Potts, M., Jahromi, B., Ansari, S. Tags: Oral abstracts Source Type: research

O-008 Functional As Opposed To Anatomical Characterization Of The Middle Cerebral Artery "M2" Divisions Can Expand The Category Of Large Vessel Occlusions Amenable For Stroke Interventions.
ConclusionPatients with a dominant branch occlusion, whether superior or inferior, had larger TTP abnormalities (>1/3rd MCA) and final infarct volumes. An estimated 37,137 AIS patients can have a dominant M2 occlusion with significant risk of ischemic injury. A functional as opposed to pure anatomical classification may allow selecting these patients for endovascular therapy.DisclosuresA. Rai: 1; C; Stryker Neurovascular. 2; C; Stryker Neurovascular. A. Tarabishy: None. P. Link: None. S. Boo: None. N. Lucke-Wold: None. J. Domico: None. J. Carpenter: None.
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Rai, A., Tarabishy, A., Link, P., Boo, S., Lucke-Wold, N., Domico, J., Carpenter, J. Tags: Oral abstracts Source Type: research

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