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Physical Consequences of Depression Predominate in the Early Post Stroke Period (P1.220)
Conclusions: Physical features of depression show up within the first few weeks after a stroke. There may be an interaction between the syndrome of post stroke fatigue and PSD. Recognition and treatment of these physical features could potentially improve the results of rehabilitation from stroke.Disclosure: Dr. Bhattacharya has nothing to disclose. Dr. Mahulikar has nothing to disclose. Dr. Kucab has received personal compensation for activities with Bayer HealthCare as an advisory board participant. Dr. Madhavan has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Bhattacharya, P., Mahulikar, A., Kucab, P., Madhavan, R. Tags: Re-admission and Stroke Outcomes Source Type: research

Reserve, Resilience and Recovery in Stroke: A Meta-Narrative Review (P3.199)
Conclusion: There is an urgent need to individualize outcomes in stroke systematically by implementing well validated concepts from various related fields to improve patient centered decision-making in acute stroke care.Disclosure: Dr. Dangayach has nothing to disclose. Dr. Grewal has nothing to disclose. Dr. Gordon has nothing to disclose. Dr. Mayer has received research support from Non-Invasive Medical Systems, Inc. and General Electric.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Dangayach, N., Grewal, H., Gordon, E., Mayer, S. Tags: Neurocritical Care: Clinical Science Source Type: research

Neuro-Psychiatry Diseases Predisposing to Mental Status Changes in Patients with Community-Acquired Pneumonia (P1.313)
Conclusions: This study indicates that MSC is frequent in patients with CAP presenting to hospital emergency departments. The etiology of MSC is diverse, with approximately half of the cases due to neuro-psychiatric conditions. In patients presenting to the emergency department with MSC, a high index of suspicion should be maintained regarding the diagnosis of pneumonia.Disclosure: Dr. Kolikonda has nothing to disclose. Dr. Wiemken has nothing to disclose. Dr. Arnold has nothing to disclose. Dr. Nakamatsu has nothing to disclose. Dr. Raghuram has nothing to disclose. Dr. Ramirez has nothing to disclose. Dr. Peyrani has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Kolikonda, M., Wiemken, T., Arnold, F., Nakamatsu, R., Raghuram, A., Ramirez, J., Peyrani, P. Tags: Other Bacterial Infections Source Type: research

Differences in Outcomes in Young and Old Patients with Intracranial Atherosclerosis (P3.233)
CONCLUSIONS: Among young patients with presumed intracranial atherosclerosis, despite similar functional outcomes and neurologic impairment, post-stroke depression appears to be more common when compared to the elderly.Disclosure: Dr. Mathew has nothing to disclose. Dr. Strohm has nothing to disclose. Dr. Cerejo has nothing to disclose. Dr. Katzan has received personal compensation for activities with Pfizer, Genetech, Inc., and Cardionet, Inc. as a member of the advisory board, consultant, and speaker. Dr. Uchino has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Mathew, J., Strohm, T., Cerejo, R., Katzan, I., Uchino, K. Tags: Stroke in the Young Source Type: research

Nursing Home Residents with Seizure Disorders/Epilepsy: Prevalence, Characteristics, and Treatment Patterns (P1.080)
Conclusions: NHRs with seizure disorder/epilepsy have substantial physical and cognitive impairment. Nearly half were prescribed combination AED therapy, and >20[percnt] took 蠅3 different AEDs, suggesting refractory epilepsy. Additional research is needed to assess treatment outcomes and further define optimal care in this population.Disclosure: Dr. Zarowitz has nothing to disclose. Dr. Allen has nothing to disclose. Dr. OShea has nothing to disclose. Dr. Wang has nothing to disclose. Dr. Semenchuk has nothing to disclose. Dr. Barghout has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Zarowitz, B., Allen, C., OShea, T., Wang, Z., Semenchuk, M., Barghout, V. Tags: Epilepsy/Clinical Neurophysiology: Geriatric Epilepsy, Epidemiology, and Health Services Source Type: research

Unique CT Perfusion Imaging in a Case of HaNDL: New Insight into Pathophysiology of Acute Attacks (P4.114)
Conclusions: The pattern of global left hemispheric hypoperfusion seen in this case supports previous hypotheses of secondary oligemia induced by a hemispheric wave of cortical spreading depression (CSD). However, the right ACA territory hypoperfusion represents a phenomenon never previously reported in this field. We speculate that the secondary vasomotor changes induced by CSD in the left hemisphere, spread to the right hemisphere via the anomalous vascular supply. Such a mechanism of direct vascular propagation through vessel gap junctions has been described in animal studies. This unique case provides a valuable contri...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Burke, M., Lamb, M., Hohol, M., Lay, C. Tags: Headache: Imaging and Other Source Type: research

An 8-Week Lifestyle Educational Program Improves Depression Related to Reduced Blood Flow (P4.392)
Conclusions: The 8-week depression recovery program was associated with significant improvement in the vast majority (90[percnt]) of participants with heart failure or stroke. In order to see if treatment was the cause of the improvement it needs to be compared to a control group that does not participate. A long-term follow-up study would also be beneficial.Disclosure: Dr. Ramirez has nothing to disclose. Dr. Antuna has nothing to disclose. Dr. Nedley holds stock and/or stock options in Nedley Health Solutions.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Ramirez, F. E., Antuna, K., Nedley, N. Tags: General Neurology: Vascular Disease and Imaging Source Type: research

The First 3 Months Post Stroke: A Unique Opportunity to Promote Exercise (P3.300)
Conclusions: Ischemic stroke patients were more likely to be exercising at three months than before their stroke, likely in part due to prescribed rehabilitation. Although this analysis is limited by unknown aerobic intensity, this subacute time period after stroke may provide a unique opportunity to incorporate exercise into patients’ lifestyles long-term.Disclosure: Dr. Garrison has nothing to disclose. Dr. Dunning has nothing to disclose. Dr. Kissela has received personal compensation for activities with Janssen and AbbVie, Inc. Dr. Woo has received research support from the National Institutes of Health. Dr. Flah...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Garrison, G., Dunning, K., Kissela, B., Woo, D., Flaherty, M., Khatri, P., Kleindorfer, D., Adeoye, O., Moomaw, C., Ferioli, S., Alwell, K., Pierce, B. Tags: Neurorehabilitation Source Type: research

Recognizing and preventing epilepsy-related mortality: A call for action
Epilepsy is associated with a high rate of premature mortality from direct and indirect effects of seizures, epilepsy, and antiseizure therapies. Sudden unexpected death in epilepsy (SUDEP) is the second leading neurologic cause of total lost potential life-years after stroke, yet SUDEP may account for less than half of all epilepsy-related deaths. Some epilepsy groups are especially vulnerable: individuals from low socioeconomic status groups and those with comorbid psychiatric illness die more often than controls. Despite clear evidence of an important public health problem, efforts to assess and prevent epilepsy-related...
Source: Neurology - February 22, 2016 Category: Neurology Authors: Devinsky, O., Spruill, T., Thurman, D., Friedman, D. Tags: Models of care, Risk factors in epidemiology, All Epilepsy/Seizures VIEWS & amp;amp; REVIEWS Source Type: research

Migraine makes the stroke grow faster?
Long associated with increased incidence of stroke,1,2 migraine has been linked with mechanisms involving the vasculature (vasospasm, arterial dissection, endothelial dysfunction, venous thrombosis), heart (patent foramen ovale), and blood (hypercoagulability).3 Since cerebral ischemia can induce cortical spreading depression, the physiologic process underlying aura, migraine with aura may theoretically represent a TIA equivalent in a subset of people. In addition to the heightened occurrence of stroke in migraineurs, a growing body of evidence suggests more dire consequences when stroke occurs, with experiments in mice wi...
Source: Neurology - November 30, 2015 Category: Neurology Authors: Tietjen, G. E., Sacco, S. Tags: Migraine, All Cerebrovascular disease/Stroke EDITORIALS Source Type: research

Suicide after stroke
In their article "Poststroke suicide attempts and completed suicides: A socioeconomic and nationwide perspective,"1 Dr. Eriksson and colleagues focused on suicide after a serious brain injury (stroke). The authors work at Umea University in Sweden and the study was supported by the Swedish Council for Health and the Swedish Research Council. The study followed more than 220,000 people for 12 years after their stroke. Within this group, the authors counted the number of people who were admitted to a hospital for a suicide attempt and the number of people who died due to suicide. They found that younger less-educated men who...
Source: Neurology - April 27, 2015 Category: Neurology Authors: Karceski, S. Tags: Stroke in young adults, Other cerebrovascular disease/ Stroke, All Cerebrovascular disease/Stroke PATIENT PAGES Source Type: research

Suicide in stroke survivors: Frequency and risk factors
Stroke is a substantial health problem worldwide. In addition to the high mortality in the acute phase, stroke causes further mortality over time due to associated comorbidities and complications, including suicidality.1 Stroke survivors have an increased risk of attempted or completed suicide.2 Identified risk factors for suicidality include depression, previous mood disorder, prior history of stroke, younger age, and cognitive impairment.2 Limited data are available on the role of socioeconomic factors such as civil status (most stroke survivors are widows or widowers), education, or income in suicidality. The recognitio...
Source: Neurology - April 27, 2015 Category: Neurology Authors: Paolucci, S., Ngeh, J. Tags: All Cerebrovascular disease/Stroke EDITORIALS Source Type: research

Poststroke suicide attempts and completed suicides: A socioeconomic and nationwide perspective
Conclusions: Both clinical and socioeconomic factors increase the risk of poststroke suicide attempts. This suggests a need for psychosocial support and suicide preventive interventions in high-risk groups of stroke patients.
Source: Neurology - April 27, 2015 Category: Neurology Authors: Eriksson, M., Glader, E.-L., Norrving, B., Asplund, K. Tags: All Cerebrovascular disease/Stroke ARTICLE Source Type: research

Sleep duration is associated with worse neurocognitive function in Hispanic/Latinos: Results of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) (I9-4A)
CONCLUSIONS: Sleep duration had an inverted J-shaped curvilinear association with neurocognitive function, such that those with longer sleep duration had worse neurocognitive scores. Study Supported by: The Hispanic Community Health Study/Study of Latinos was carried out as a collaborative study supported by contracts from the National Heart, Lung, and Blood Institute (NHLBI) to the University of North Carolina (N01-HC65233), University of Miami (N01-HC65234), Albert Einstein College of Medicine (N01-HC65235), Northwestern University (N01-HC65236), and San Diego State University (N01-HC65237). The following Institutes/Cent...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ramos, A., Tarraf, W., Daviglus, M., Davis, S., Gallo, L., Mossavar-Rahmani, Y., Penedo, F., Redline, S., Rundek, T., Sacco, R., Sotres-Alvarez, D., Wright, C., Zee, P., Gonzalez, H. Tags: Treating Dementia in an Age of Mixed Disease Data Blitz Presentations Source Type: research

Predictors for Failure to Follow-Up in Clinic After Ischemic Stroke (P1.010)
CONCLUSIONS: Clinicians should be mindful that follow-up after stroke is likely predicted by multiple factors, including more severe stroke on admission, discharge disposition, and lack of prior outpatient care. More efforts to address follow-up after ischemic stroke should be enacted to prevent recurrent strokes in this high-risk population.Disclosure: Dr. Osteraas has nothing to disclose. Dr. Cherian has nothing to disclose. Dr. Cutting has nothing to disclose. Dr. Conners has nothing to disclose. Dr. Song has nothing to disclose. Dr. Lee has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Osteraas, N., Cherian, L., Cutting, S., Conners, J., Song, S., Lee, V. Tags: Cerebrovascular Disease and Interventional Neurology Poster Discussion Session Source Type: research

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