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Source: International Journal of Stroke
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Total 27 results found since Jan 2013.

Quality in Acute Stroke Care (QASC): process evaluation of an intervention to improve the management of fever, hyperglycemia, and swallowing dysfunction following acute stroke
BackgroundOur randomized controlled trial of a multifaceted evidence‐based intervention for improving the inpatient management of fever, hyperglycemia, and swallowing dysfunction in the first three‐days following stroke improved outcomes at 90 days by 15%. We designed a quantitative process evaluation to further explain and illuminate this finding. MethodsBlinded retrospective medical record audits were undertaken for patients from 19 stroke units prior to and following the implementation of three multidisciplinary evidence‐based protocols (supported by team‐building workshops, and site‐based education and suppor...
Source: International Journal of Stroke - December 1, 2013 Category: Neurology Authors: Peta Drury, Christopher Levi, Catherine D'Este, Patrick McElduff, Elizabeth McInnes, Jennifer Hardy, Simeon Dale, N Wah Cheung, Jeremy M Grimshaw, Clare Quinn, Jeanette Ward, Malcolm Evans, Dominique Cadilhac, Rhonda Griffiths, Sandy Middleton Tags: Research Source Type: research

Current status of acute stroke management in Korea: a report on a multicenter, comprehensive acute stroke registry
There are limited data on the utilization of diagnostics and the variation of treatments at the national level in acute stroke care. Clinical Research Center for Stroke – 5th division stroke registry aimed to describe stroke statistics and quality of care in Korea and to implement quality indicators. Clinical Research Center for Stroke – 5th division registry was established in April 2008 and covers pretreatment demographics, medical and stroke severity measures, diagnostic evaluation, hyperacute revascularization, in‐hospital management, discharge disposition, quality indicators, and long‐term functional outcomes....
Source: International Journal of Stroke - November 21, 2013 Category: Neurology Authors: Beom Joon Kim, Moon‐Ku Han, Tai Hwan Park, Sang‐Soon Park, Kyung Bok Lee, Byung‐Chul Lee, Kyung‐Ho Yu, Jae Kwan Cha, Dae‐Hyun Kim, Jun Lee, Soo Joo Lee, Youngchai Ko, Jong‐Moo Park, Kyusik Kang, Yong‐Jin Cho, Keun‐Sik Hong, Ki‐Hyun Cho, Tags: Panorama Source Type: research

Endovascular therapeutic hypothermia for acute ischemic stroke: ICTuS 2/3 protocol
Therapeutic hypothermia improves neurological outcome after out‐of‐hospital cardiac arrest or neonatal hypoxic–ischemic injury. Although supported by preclinical evidence, therapeutic hypothermia for acute stroke remains under study. In the Intravascular Cooling in the Treatment of Stroke (ICTuS) trial, awake stroke patients were successfully cooled using an endovascular cooling catheter and a novel antishivering regimen. In the ICTuS‐L study, the combination of endovascular hypothermia and thrombolysis proved feasible; while hypothermia was associated with no increased risk of bleeding complications, there was an ...
Source: International Journal of Stroke - November 10, 2013 Category: Neurology Authors: Patrick D. Lyden, Thomas M. Hemmen, James Grotta, Karen Rapp, Rema Raman Tags: Protocols Source Type: research

Reducing recurrent stroke: Methodology of the motivational interviewing in stroke (MIST) randomized clinical trial
DiscussionThe results of the motivational interviewing in stroke trial will add to our understanding of whether motivational interviewing may be potentially beneficial in the management of stroke and other diseases where similar lifestyle factors or medication adherence are relevant.
Source: International Journal of Stroke - October 27, 2013 Category: Neurology Authors: Rita Krishnamurthi, Emma Witt, Suzanne Barker‐Collo, Kathryn McPherson, Kelly Davis‐Martin, Derrick Bennett, Elaine Rush, Flora Suh, Nicola Starkey, Varsha Parag, Yogini Rathnasabapathy, Amy Jones, Paul Brown, Braden Te Ao, Valery L. Feigin, Tags: Protocols (Invited) Source Type: research

Establishment of an effective acute stroke telemedicine program for Australia: protocol for the Victorian Stroke Telemedicine project
RationaleUrgent treatment of acute stroke in rural Australia is problematic partly because of limited access to medical specialists. Utilization of telemedicine could improve delivery of acute stroke treatments in rural communities. AimThe study aims to demonstrate enhanced clinical decision making for use of thrombolysis within 4·5 h of ischemic stroke symptom onset in a rural setting using a telemedicine specialist support model. DesignA formative program evaluation research design was used. The Victorian Stroke Telemedicine program was developed and will be evaluated over five stages to ensure successful implementati...
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: Dominique A. Cadilhac, Natasha Moloczij, Sonia Denisenko, Helen Dewey, Peter Disler, Bruce Winzar, Ian Mosley, Geoffrey A. Donnan, Christopher Bladin Tags: Protocols Source Type: research

Study protocol of the Restore4Stroke self‐management study: a multicenter randomized controlled trial in stroke patients and their partners
DiscussionIf effective, the results of this study will enable stroke patients and their partners to deal better with the lasting consequences of stroke. In the context of the growing number of people returning home after stroke, a large number of people may profit from this intervention.
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: Nienke S. Tielemans, Johanna M. A. Visser‐Meily, Vera P. M. Schepers, Marcel W. M. Post, Derick T. Wade, Caroline M. Heugten Tags: Protocols Source Type: research

Protocol for seizure prophylaxis following intracerebral hemorrhage study (SPICH): a randomized, double‐blind, placebo‐controlled trial of short‐term sodium valproate prophylaxis in patients with acute spontaneous supratentorial intracerebral hemorrhage
This study aims to determine if short‐duration sodium valproate prevents seizure onset or improves the survival and neurological outcome in adults after acute spontaneous supratentorial intracerebral hemorrhage. DesignIn this randomized, double blinded, placebo‐controlled trial, 258 patients meeting the inclusion criteria will be enrolled in the Department of Neurosurgery, West China Hospital. In addition to standard care, patients will be randomly assigned to receive seven‐day prophylaxis of sodium valproate 500 mg daily (alternatively 400 mg daily by intravenous infusion in 250 ml 0·9% normal saline) or matc...
Source: International Journal of Stroke - September 16, 2013 Category: Neurology Authors: X. Hu, Y. Fang, H. Li, W. Liu, S. Lin, M. Fu, X. Li, X. Cao, H. Zhang, C. You, M. Liu Tags: Protocols Source Type: research

The CLOQS trial protocol: a cluster‐randomized trial evaluating a simple, low‐cost intervention to reduce treatment times in acute stroke
The objective of the Countdown Lights to Optimize Quality in acute Stroke (CLOQS) trial is to determine whether a simple, low‐cost organizational behavior intervention, a large, red stopwatch timer attached to the stretcher upon arrival, will decrease door‐to‐scanner and door‐to‐needle treatment times for tissue plasminogen activator‐treated patients. DesignA multicenter, time‐clustered randomized control trial. The stopwatch timers will be used in Emergency Departments for all acute stroke patients across the University of Toronto Stroke Program. The order of intervention (ON) and control (OFF) blocks will b...
Source: International Journal of Stroke - September 5, 2013 Category: Neurology Authors: Richard H. Swartz, Michelle N. Sicard, Frank L. Silver, Gustavo Saposnik, David J. Gladstone, Jennifer Breaton, Sharon Ramagnano, Jacques Lee, Richard I. Aviv, Jiming Fang, Merrick F. Zwarenstein, Tags: Protocols Source Type: research

The impact of demographic and logistic factors on effectiveness and safety of IV thrombolysis in patients with acute ischemic stroke in a rural hospital in southeastern Poland
Source: International Journal of Stroke - July 23, 2013 Category: Neurology Authors: Piotr Sobolewski, Wiktor Szczuchniak, Renata Hatalska‐Żerebiec, Anna Sobota, Monika Śledzińska‐Dźwigał Tags: Letter to the editor Source Type: research

Burden of stroke in Estonia
Estonia is the smallest of the three Baltic countries. The decline in incidence of first‐ever stroke during the 1990s has left Tartu, Estonia with a relatively low stroke incidence. However, the incidence rates for younger age groups, and the 28‐day case fatality rate are higher compared with several other studies. Developments in the national health care system in recent years have been positive: the decline of mortality rate of stroke in Estonia is greater than the European Union average. However, the mortality of cardiovascular diseases is higher compared with several European countries. The prevalence of most strok...
Source: International Journal of Stroke - April 1, 2013 Category: Neurology Authors: Janika Kõrv, Riina Vibo Tags: Panorama Source Type: research

WSO Stroke Education Program in Vietnam 2008–2011: 8596 hospital doctors attended in 58 cities and received a certificate from the WSO and the Ministry of Health
Source: International Journal of Stroke - March 15, 2013 Category: Neurology Authors: Michael Brainin, Bo Norrving Tags: Editorial Source Type: research

Determinants of early case‐fatality among stroke patients in Maputo, Mozambique and impact of in‐hospital complications
The burden of stroke is increasing in developing countries that struggle to manage it efficiently. We identified determinants of early case‐fatality among stroke patients in Maputo, Mozambique, to assess the impact of in‐hospital complications. Patients admitted to any hospital in Maputo with a new stroke event were prospectively registered (n = 651) according to the World Health Organization's STEPwise approach, in 2005–2006. We assessed the determinants of in‐hospital and 28‐day fatality, independently of age, gender and education, and computed population attributable fractions. In‐hospital mortality was ...
Source: International Journal of Stroke - January 1, 2013 Category: Neurology Authors: Joana Gomes, Albertino Damasceno, Carla Carrilho, Vitória Lobo, Hélder Lopes, Tavares Madede, Pius Pravinrai, Carla Silva‐Matos, Domingos Diogo, Ana Azevedo, Nuno Lunet Tags: Panorama Source Type: research