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Source: International Journal of Stroke
Condition: Thrombosis
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Total 40 results found since Jan 2013.
Positional occlusion of the internal carotid artery by thrombus plugging causing transient ischemic attack
Source: International Journal of Stroke - September 18, 2014 Category: Neurology Authors: Han‐Gil Jeong, Keun‐Hwa Jung, Jae‐Kyu Roh Tags: Letter to the editor Source Type: research
Management of acute stroke in patients taking novel oral anticoagulants
Each year, 1·0–2·0% of individuals with atrial fibrillation and 0·1–0·2% of those with venous thromboembolism who are receiving one of the novel oral anticoagulants (dabigatran, rivaroxaban, or apixaban) can be expected to experience an acute ischemic stroke. Additionally, 0·2–0·5% of individuals with atrial fibrillation who are receiving one of the novel oral anticoagulants can be expected to experience an intracranial hemorrhage. This opinion piece addresses the current literature and offers practical approaches to the management of patients receiving novel oral anticoagulants who present with an ischemic or ...
Source: International Journal of Stroke - June 1, 2014 Category: Neurology Authors: Graeme J. Hankey, Bo Norrving, Werner Hacke, Thorsten Steiner Tags: Review Source Type: research
The THRIVE score strongly predicts outcomes in patients treated with the Solitaire device in the SWIFT and STAR trials
ConclusionsThe THRIVE score strongly predicts clinical outcome and mortality in patients treated with the Solitaire device in the SWIFT and STAR trials. The lack of interaction between THRIVE and procedure‐specific elements such as vessel recanalization or device choice makes the THRIVE score a reasonable candidate for use as a patient selection criterion in stroke clinical trials.
Source: International Journal of Stroke - May 22, 2014 Category: Neurology Authors: Alexander C. Flint, Sean P. Cullen, Vivek A. Rao, Bonnie S. Faigeles, Vitor M. Pereira, Elad I. Levy, Tudor G. Jovin, David S. Liebeskind, Raul G. Nogueira, Reza Jahan, Jeffrey L. Saver, Tags: Research Source Type: research
Three‐dimensional analysis of the left atrial appendage for detecting paroxysmal atrial fibrillation in acute ischemic stroke
ConclusionsLeft atrial appendage volumetric analysis by real‐time three‐dimensional transesophageal echocardiography is a promising method for detecting paroxysmal atrial fibrillation in acute cerebral infarction or transient ischemic attack.
Source: International Journal of Stroke - March 12, 2014 Category: Neurology Authors: Koji Tanaka, Masatoshi Koga, Kazuaki Sato, Rieko Suzuki, Kazuo Minematsu, Kazunori Toyoda Tags: Research Source Type: research
Prehospital factors determining regional variation in thrombolytic therapy in acute ischemic stroke
ConclusionsThese results suggest that the larger proportion of patients arriving within 4·5 h in the centralized model might be related to a lower threshold to use emergency services to transport stroke patients and partly to preferential referral of thrombolysis candidates.
Source: International Journal of Stroke - December 23, 2013 Category: Neurology Authors: Maarten M. H. Lahr, Patrick C. A. J. Vroomen, Gert‐Jan Luijckx, Durk‐Jouke Zee, Ronald Vos, Erik Buskens Tags: Research Source Type: research
Processes of early stroke care and hospital costs
ConclusionsEarly care in agreement with key guidelines recommendations for the management of patients with stroke may be associated with hospital savings.
Source: International Journal of Stroke - December 19, 2013 Category: Neurology Authors: Marie Louise Svendsen, Lars H. Ehlers, Heidi H. Hundborg, Annette Ingeman, Søren P. Johnsen Tags: Research Source Type: research
The impact of cerebrovascular disease in Panama
ConclusionSince 2013, both hospitals' intravenous thrombolytic therapy program has been successfully applied as public health policy. A successful campaign on healthy lifestyle must be strengthened through a comprehensive approach with other public sectors in order to have an impact on the population, particularly in children and adolescents.
Source: International Journal of Stroke - November 21, 2013 Category: Neurology Authors: Fernando Gracia, Aron Benzadon, Marco Gonzalez‐Castellon, Blas Armien Tags: Research Source Type: research
Reperfusion after 4·5 hours reduces infarct growth and improves clinical outcomes
ConclusionsThrombolysis 4·5–6 h after stroke onset reduced infarct growth and increased the rate of reperfusion, which was associated with good neurological and functional outcome.
Source: International Journal of Stroke - November 21, 2013 Category: Neurology Authors: Miguel R. Picanço, Søren Christensen, Bruce C. V. Campbell, Leonid Churilov, Mark W. Parsons, Patricia M. Desmond, P. Alan Barber, Christopher R. Levi, Christopher F. Bladin, Geoffrey A. Donnan, Stephen M. Davis, Tags: Research Source Type: research
Body mass index and acute ischemic stroke outcomes
ConclusionsBeing overweight or obese is associated with a better functional outcome and reduced mortality in patients of acute ischemic stroke. However, the definition of an ‘optimal’ body mass index, in relation to stroke outcomes, may be affected by age, gender, and use of thrombolytic therapy.
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: M. Saini, M. Saqqur, A. Shuaib, Tags: Research Source Type: research
Influence of racial differences on outcomes after thrombolytic therapy in acute ischemic stroke
ConclusionsThese results do not suggest a differential response to tissue plasminogen activator based on race ethnicity. Among Asians, data were particularly sparse, and results should be interpreted with caution.
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: Nishant K. Mishra, Pitchaiah Mandava, Christopher Chen, James Grotta, Kennedy R. Lees, Thomas A. Kent, Tags: Research Source Type: research
Do‐not‐resuscitate (DNR) orders in patients with intracerebral hemorrhage
ConclusionsIn addition to confirming the role of known intracerebral hemorrhage prognostic factors in do‐not‐resuscitate decision‐making, our results demonstrate that do‐not‐resuscitate orders led to less active care of intracerebral hemorrhage patients.
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: Katri Silvennoinen, Atte Meretoja, Daniel Strbian, Jukka Putaala, Markku Kaste, Turgut Tatlisumak Tags: Research Source Type: research
Translational perspectives on perfusion–diffusion mismatch in ischemic stroke
Magnetic resonance imaging has tremendous potential to illuminate ischemic stroke pathophysiology and guide rational treatment decisions. Clinical applications to date have been largely limited to trials. However, recent analyses of the major clinical studies have led to refinements in selection criteria and improved understanding of the potential implications for the risk vs. benefit of thrombolytic therapy. In parallel, preclinical studies have provided complementary information on the evolution of stroke that is difficult to obtain in humans due to the requirement for continuous or repeated imaging and pathological veri...
Source: International Journal of Stroke - October 1, 2013 Category: Neurology Authors: Bruce C. V. Campbell, I. Mhairi Macrae Tags: Review Source Type: research
Predictors of in‐hospital death and symptomatic intracranial hemorrhage in patients with acute ischemic stroke treated with thrombolytic therapy: Paul Coverdell Acute Stroke Registry 2008–2012
ConclusionsIn this study of acute ischemic stroke patients, older age, male gender, National Institutes of Health Stroke Scale score, history of myocardial infarction or coronary artery disease, and history of atrial fibrillation were associated with increased in‐hospital death among patients receiving intravenous tissue plasminogen activator. Among patients treated with intravenous tissue plasminogen activator, in‐hospital mortality and symptomatic intracerebral hemorrhage rates were similar between those treated within three‐hours of time last known to be well and those treated between three and 4·5 hours after this time.
Source: International Journal of Stroke - September 12, 2013 Category: Neurology Authors: Xin Tong, Mary G. George, Quanhe Yang, Cathleen Gillespie Tags: Research Source Type: research
Intravenous thrombolytic therapy for acute ischemic stroke in Tuzla Canton, Bosnia and Herzegovina
Source: International Journal of Stroke - September 11, 2013 Category: Neurology Authors: Dževdet Smajlović, Denisa Salihović, Leila Avdić, Zikrija Dostović, Omer Ć. Ibrahimagić, Mirjana Vidović Tags: Letter to the editor Source Type: research
A multicenter, randomized, double‐blinded, placebo‐controlled phase III study of Clot Lysis Evaluation of Accelerated Resolution of Intraventricular Hemorrhage (CLEAR III)
BackgroundIn adults, intraventricular thrombolytic therapy with recombinant tissue plasminogen activator (rtPA) facilitates resolution of intraventricular haemorrhage (IVH), reduces intracranial pressure, decreases duration of cerebrospinal fluid diversion, and may ameliorate direct neural injury. We hypothesize that patients with small parenchymal haematoma volumes (<30 cc) and relatively large IVH causing acute obstructive hydrocephalus would have improved clinical outcomes when given injections of low‐dose rtPA to accelerate lysis and evacuation of IVH compared with placebo.
MethodsThe Clot Lysis Evaluation of Ac...
Source: International Journal of Stroke - August 1, 2013 Category: Neurology Authors: Wendy C. Ziai, Stanley Tuhrim, Karen Lane, Nichol McBee, Kennedy Lees, Jesse Dawson, Kenneth Butcher, Paul Vespa, David W. Wright, Penelope M. Keyl, A. David Mendelow, Carlos Kase, Christine Wijman, Marc Lapointe, Sayona John, Richard Thompson, Carol Thom Tags: Research Source Type: research
