From ownership to custodianship of tumor biopsy tissue in genomic testing: a mixed methods study of patient views
Oncologist. 2024 May 7:oyae074. doi: 10.1093/oncolo/oyae074. Online ahead of print.ABSTRACTTumor mutation profiling (MP) is often conducted on tissue from biopsies conducted for clinical purposes (diagnostic tissue). We aimed to explore the views of patients with cancer on who should own tumor biopsy tissue, pay for its storage, and decide on its future use; and determine their attitudes to and predictors of undergoing additional biopsies if required for research purposes. In this mixed methods, cross-sectional study, patients with advanced solid cancers enrolled in the Molecular Screening and Therapeutics Program (n = 397...
Source: The Oncologist - May 7, 2024 Category: Cancer & Oncology Authors: Megan C Best Phyllis Butow Jacqueline Savard Ainsley J Newson Rachel Campbell Sabina Vatter Christine E Napier Nicci Bartley Katherine Tucker Mandy L Ballinger David M Thomas PiGeOn Project Source Type: research
EGFR, HER2, and MET gene amplification and protein expression profiles in biliary tract cancer and their prognostic significance
CONCLUSION: Our data suggested that MET, HER2, and EGFR might be potential therapeutic targets and that their co-expression is a strong prognostic factor for BTCs.PMID:38709907 | DOI:10.1093/oncolo/oyae076 (Source: The Oncologist)
Source: The Oncologist - May 6, 2024 Category: Cancer & Oncology Authors: Yeseul Kim Seungyun Jee Hyunsung Kim Seung Sam Paik Dongho Choi Su Hyun Yoo Su-Jin Shin Source Type: research
Association of opioid use with survival in patients with cancer treated with immune checkpoint inhibitors: it is time for evidence-based behaviors
Oncologist. 2024 Apr 30:oyae081. doi: 10.1093/oncolo/oyae081. Online ahead of print.ABSTRACTCancer is a leading cause of morbidity and mortality worldwide, with pain experienced by most patients undergoing cancer treatment. Opioids are the recommended treatment for cancer pain management, but recent studies suggest a negative association between opioid use and survival rates among patients undergoing immunotherapy. However, conclusions cannot be drawn regarding causality from these observational data. Immunotherapy, which boosts the body's immune system to fight cancer cells, has emerged as a promising treatment option for...
Source: The Oncologist - April 30, 2024 Category: Cancer & Oncology Authors: Raffaele Giusti Giampiero Porzio Marco Maltoni Marco Filetti Arturo Cuomo Elena Bandieri Dario Trapani Eduardo Bruera Source Type: research
Rational treatment options for T1/2N0M0 squamous cell carcinoma of the anal canal: a population-based study combined with external validation
CONCLUSION: The nomogram developed in this study effectively and comprehensively evaluated the prognosis of patients with cT1/2N0M0 squamous cell carcinoma of the anal canal. Local excision is recommended for low risk patients, radiotherapy for moderate-risk patients, and radiotherapy or chemoradiotherapy for high-risk patients.PMID:38688457 | DOI:10.1093/oncolo/oyae068 (Source: The Oncologist)
Source: The Oncologist - April 30, 2024 Category: Cancer & Oncology Authors: Xue Shao Qiulei Zhang Ying Huo Chang Lu Source Type: research
Association of opioid use with survival in patients with cancer treated with immune checkpoint inhibitors: it is time for evidence-based behaviors
Oncologist. 2024 Apr 30:oyae081. doi: 10.1093/oncolo/oyae081. Online ahead of print.ABSTRACTCancer is a leading cause of morbidity and mortality worldwide, with pain experienced by most patients undergoing cancer treatment. Opioids are the recommended treatment for cancer pain management, but recent studies suggest a negative association between opioid use and survival rates among patients undergoing immunotherapy. However, conclusions cannot be drawn regarding causality from these observational data. Immunotherapy, which boosts the body's immune system to fight cancer cells, has emerged as a promising treatment option for...
Source: The Oncologist - April 30, 2024 Category: Cancer & Oncology Authors: Raffaele Giusti Giampiero Porzio Marco Maltoni Marco Filetti Arturo Cuomo Elena Bandieri Dario Trapani Eduardo Bruera Source Type: research
Rational treatment options for T1/2N0M0 squamous cell carcinoma of the anal canal: a population-based study combined with external validation
CONCLUSION: The nomogram developed in this study effectively and comprehensively evaluated the prognosis of patients with cT1/2N0M0 squamous cell carcinoma of the anal canal. Local excision is recommended for low risk patients, radiotherapy for moderate-risk patients, and radiotherapy or chemoradiotherapy for high-risk patients.PMID:38688457 | DOI:10.1093/oncolo/oyae068 (Source: The Oncologist)
Source: The Oncologist - April 30, 2024 Category: Cancer & Oncology Authors: Xue Shao Qiulei Zhang Ying Huo Chang Lu Source Type: research
Association of opioid use with survival in patients with cancer treated with immune checkpoint inhibitors: it is time for evidence-based behaviors
Oncologist. 2024 Apr 30:oyae081. doi: 10.1093/oncolo/oyae081. Online ahead of print.ABSTRACTCancer is a leading cause of morbidity and mortality worldwide, with pain experienced by most patients undergoing cancer treatment. Opioids are the recommended treatment for cancer pain management, but recent studies suggest a negative association between opioid use and survival rates among patients undergoing immunotherapy. However, conclusions cannot be drawn regarding causality from these observational data. Immunotherapy, which boosts the body's immune system to fight cancer cells, has emerged as a promising treatment option for...
Source: The Oncologist - April 30, 2024 Category: Cancer & Oncology Authors: Raffaele Giusti Giampiero Porzio Marco Maltoni Marco Filetti Arturo Cuomo Elena Bandieri Dario Trapani Eduardo Bruera Source Type: research
Rational treatment options for T1/2N0M0 squamous cell carcinoma of the anal canal: a population-based study combined with external validation
CONCLUSION: The nomogram developed in this study effectively and comprehensively evaluated the prognosis of patients with cT1/2N0M0 squamous cell carcinoma of the anal canal. Local excision is recommended for low risk patients, radiotherapy for moderate-risk patients, and radiotherapy or chemoradiotherapy for high-risk patients.PMID:38688457 | DOI:10.1093/oncolo/oyae068 (Source: The Oncologist)
Source: The Oncologist - April 30, 2024 Category: Cancer & Oncology Authors: Xue Shao Qiulei Zhang Ying Huo Chang Lu Source Type: research
Association of opioid use with survival in patients with cancer treated with immune checkpoint inhibitors: it is time for evidence-based behaviors
Oncologist. 2024 Apr 30:oyae081. doi: 10.1093/oncolo/oyae081. Online ahead of print.ABSTRACTCancer is a leading cause of morbidity and mortality worldwide, with pain experienced by most patients undergoing cancer treatment. Opioids are the recommended treatment for cancer pain management, but recent studies suggest a negative association between opioid use and survival rates among patients undergoing immunotherapy. However, conclusions cannot be drawn regarding causality from these observational data. Immunotherapy, which boosts the body's immune system to fight cancer cells, has emerged as a promising treatment option for...
Source: The Oncologist - April 30, 2024 Category: Cancer & Oncology Authors: Raffaele Giusti Giampiero Porzio Marco Maltoni Marco Filetti Arturo Cuomo Elena Bandieri Dario Trapani Eduardo Bruera Source Type: research
Rational treatment options for T1/2N0M0 squamous cell carcinoma of the anal canal: a population-based study combined with external validation
CONCLUSION: The nomogram developed in this study effectively and comprehensively evaluated the prognosis of patients with cT1/2N0M0 squamous cell carcinoma of the anal canal. Local excision is recommended for low risk patients, radiotherapy for moderate-risk patients, and radiotherapy or chemoradiotherapy for high-risk patients.PMID:38688457 | DOI:10.1093/oncolo/oyae068 (Source: The Oncologist)
Source: The Oncologist - April 30, 2024 Category: Cancer & Oncology Authors: Xue Shao Qiulei Zhang Ying Huo Chang Lu Source Type: research
Association of opioid use with survival in patients with cancer treated with immune checkpoint inhibitors: it is time for evidence-based behaviors
Oncologist. 2024 Apr 30:oyae081. doi: 10.1093/oncolo/oyae081. Online ahead of print.ABSTRACTCancer is a leading cause of morbidity and mortality worldwide, with pain experienced by most patients undergoing cancer treatment. Opioids are the recommended treatment for cancer pain management, but recent studies suggest a negative association between opioid use and survival rates among patients undergoing immunotherapy. However, conclusions cannot be drawn regarding causality from these observational data. Immunotherapy, which boosts the body's immune system to fight cancer cells, has emerged as a promising treatment option for...
Source: The Oncologist - April 30, 2024 Category: Cancer & Oncology Authors: Raffaele Giusti Giampiero Porzio Marco Maltoni Marco Filetti Arturo Cuomo Elena Bandieri Dario Trapani Eduardo Bruera Source Type: research
Rational treatment options for T1/2N0M0 squamous cell carcinoma of the anal canal: a population-based study combined with external validation
CONCLUSION: The nomogram developed in this study effectively and comprehensively evaluated the prognosis of patients with cT1/2N0M0 squamous cell carcinoma of the anal canal. Local excision is recommended for low risk patients, radiotherapy for moderate-risk patients, and radiotherapy or chemoradiotherapy for high-risk patients.PMID:38688457 | DOI:10.1093/oncolo/oyae068 (Source: The Oncologist)
Source: The Oncologist - April 30, 2024 Category: Cancer & Oncology Authors: Xue Shao Qiulei Zhang Ying Huo Chang Lu Source Type: research
Perception of Polish patients with cancer of the ethical and legal issues related to biobank research
CONCLUSIONS: Since biobanks generate ethical and legal issues related to informed consent, data protection and storage, as well as the sharing of biosamples, tissue ownership, and profit sharing, that may discourage patients from donation, when asking a patient for a donation, healthcare professionals should communicate in a donor-centered manner and address patients' ethical and moral concerns related to donation and offer resources to help manage these concerns.PMID:38666716 | DOI:10.1093/oncolo/oyae078 (Source: The Oncologist)
Source: The Oncologist - April 26, 2024 Category: Cancer & Oncology Authors: Jan Domaradzki Justyna Czekajewska Dariusz Walkowiak Source Type: research
Perception of Polish patients with cancer of the ethical and legal issues related to biobank research
CONCLUSIONS: Since biobanks generate ethical and legal issues related to informed consent, data protection and storage, as well as the sharing of biosamples, tissue ownership, and profit sharing, that may discourage patients from donation, when asking a patient for a donation, healthcare professionals should communicate in a donor-centered manner and address patients' ethical and moral concerns related to donation and offer resources to help manage these concerns.PMID:38666716 | DOI:10.1093/oncolo/oyae078 (Source: The Oncologist)
Source: The Oncologist - April 26, 2024 Category: Cancer & Oncology Authors: Jan Domaradzki Justyna Czekajewska Dariusz Walkowiak Source Type: research
Perception of Polish patients with cancer of the ethical and legal issues related to biobank research
CONCLUSIONS: Since biobanks generate ethical and legal issues related to informed consent, data protection and storage, as well as the sharing of biosamples, tissue ownership, and profit sharing, that may discourage patients from donation, when asking a patient for a donation, healthcare professionals should communicate in a donor-centered manner and address patients' ethical and moral concerns related to donation and offer resources to help manage these concerns.PMID:38666716 | DOI:10.1093/oncolo/oyae078 (Source: The Oncologist)
Source: The Oncologist - April 26, 2024 Category: Cancer & Oncology Authors: Jan Domaradzki Justyna Czekajewska Dariusz Walkowiak Source Type: research
