Computational modeling of light processing in the habenula and dorsal raphe based on laser ablation of functionally-defined cells
The habenula is a major regulator of serotonergic neurons in the dorsal raphe, and thus of brain state. The functional connectivity between these regions is incompletely characterized. Here, we use the ability... (Source: BMC Neuroscience)
Source: BMC Neuroscience - April 16, 2024 Category: Neuroscience Authors: Ruey-Kuang Cheng, N. Suhas Jagannathan, Ahmad Ismat Kathrada, Suresh Jesuthasan and Lisa Tucker-Kellogg Tags: Research Source Type: research

The effects of multi-colour light filtering glasses on human brain wave activity
The prevalence of electronic screens in modern society has significantly increased our exposure to high-energy blue and violet light wavelengths. Accumulating evidence links this exposure to adverse visual and... (Source: BMC Neuroscience)
Source: BMC Neuroscience - April 12, 2024 Category: Neuroscience Authors: Katherine Boere and Olave E. Krigolson Tags: Research Source Type: research

The effect of early mobilisation ( <  14 days) on pathophysiological and functional outcomes in animals with induced spinal cord injury: a systematic review with meta-analysis
The optimum time to mobilise (standing, walking) following spinal cord injury (SCI) is unknown but may have implications for patient outcomes. There are no high-quality experimental studies that examine this i... (Source: BMC Neuroscience)
Source: BMC Neuroscience - March 25, 2024 Category: Neuroscience Authors: Natalie Gray, Junaid Shaikh, Alison Cowley, Vicky Goosey-Tolfrey, Pip Logan, Nasir Quraishi and Vicky Booth Tags: Research Source Type: research

Neuroscience of taste: unlocking the human taste code
Since antiquity human taste has been divided into 4 –5 taste qualities. We realized in the early 1970s that taste qualities vary between species and that the sense of taste in species closer to humans such as p... (Source: BMC Neuroscience)
Source: BMC Neuroscience - March 21, 2024 Category: Neuroscience Authors: G öran Hellekant Tags: Review Source Type: research

Auditory brainstem responses are resistant to pharmacological modulation in Sprague Dawley wild-type and Neurexin1 α knockout rats
Sensory processing in the auditory brainstem can be studied with auditory brainstem responses (ABRs) across species. There is, however, a limited understanding of ABRs as tools to assess the effect of pharmac... (Source: BMC Neuroscience)
Source: BMC Neuroscience - March 15, 2024 Category: Neuroscience Authors: Samuel Marashli, Philipp Janz and Roger L Redondo Tags: Research Source Type: research

Serum interleukin-17 A and homocysteine levels in children with autism
This study aimed to explore the potential link between serum levels of vitamin B12 and homocysteine (... (Source: BMC Neuroscience)
Source: BMC Neuroscience - March 12, 2024 Category: Neuroscience Authors: Hui Li, Yunhao Dang and Ying Yan Tags: Research Source Type: research

Administration methods and dosage of poly(lactic acid)-glycol intervention to myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalitis mice
Myelin oligodendrocyte glycoprotein-associated disorders (MOGAD) is an autoimmune central nervous system disease. Antigen-specific immune tolerance using nanoparticles such as Polylactic-co-glycolic acid (PLGA... (Source: BMC Neuroscience)
Source: BMC Neuroscience - March 11, 2024 Category: Neuroscience Authors: Amy E. Wright, Shuhei Nishiyama, Patrick Han, Philip Kong and Michael Levy Tags: Research Source Type: research

Discrimination of the moving direction is improved depending on the pattern of the mechanical tactile stimulation intervention
The mechanical tactile stimulation, such as plastic pins and airflow-driven membrane, induces cortical activity. The cortical activity depends on the mechanical tactile stimulation pattern. Therefore, the stim... (Source: BMC Neuroscience)
Source: BMC Neuroscience - March 5, 2024 Category: Neuroscience Authors: Yuki Maruyama, Sho Kojima and Hideaki Onishi Tags: Research Source Type: research

Prodromal Parkinson disease signs are predicted by a whole-blood inflammatory transcriptional signature in young Pink1 −/− rats
Parkinson disease (PD) is the fastest growing neurodegenerative disease. The molecular pathology of PD in the prodromal phase is poorly understood; as such, there are no specific prognostic or diagnostic tests... (Source: BMC Neuroscience)
Source: BMC Neuroscience - March 4, 2024 Category: Neuroscience Authors: Sarah A. Lechner, David G. S. Barnett, Stephen C. Gammie and Cynthia A. Kelm-Nelson Tags: Research Source Type: research

Defined co-cultures of glutamatergic and GABAergic neurons with a mutation in DISC1 reveal aberrant phenotypes in GABAergic neurons
Mutations in the gene DISC1 are associated with increased risk for schizophrenia, bipolar disorder and major depression. The study of mutated DISC1 represents a well-known and comprehensively characterized approa... (Source: BMC Neuroscience)
Source: BMC Neuroscience - March 4, 2024 Category: Neuroscience Authors: Johanna Heider, Aaron Stahl, Denise Sperlich, Sophia-Marie Hartmann, Sabrina Vogel, Ricarda Breitmeyer, Markus Templin and Hansj ürgen Volkmer Tags: Research Source Type: research

Resistance training modifies of serum levels of matrix metalloproteinase 2 and tissue inhibitor of matrix metalloproteinases in multiple sclerosis women - a randomized controlled trail
The objectives of the present study was to investigate the effects of resistance training (RT) on serum levels of controlling blood-brain barrier (BBB) permeability indices and cognitive performance in MS wome... (Source: BMC Neuroscience)
Source: BMC Neuroscience - March 4, 2024 Category: Neuroscience Authors: Nasrin Niazi Nezhad, Abdolhossein Parnow, Kianoosh Khamoushian, Rasoul Eslami and Julien S Baker Tags: Research Source Type: research

State-transition dynamics of resting-state functional magnetic resonance imaging data: model comparison and test-to-retest analysis
Electroencephalogram (EEG) microstate analysis entails finding dynamics of quasi-stable and generally recurrent discrete states in multichannel EEG time series data and relating properties of the estimated sta... (Source: BMC Neuroscience)
Source: BMC Neuroscience - March 4, 2024 Category: Neuroscience Authors: Saiful Islam, Pitambar Khanra, Johan Nakuci, Sarah F. Muldoon, Takamitsu Watanabe and Naoki Masuda Tags: Research Source Type: research

Current state of neuroprotective therapy using antibiotics in human traumatic brain injury and animal models
TBI is a leading cause of death and disability in young people and older adults worldwide. There is no gold standard treatment for TBI besides surgical interventions and symptomatic relief. Post-injury infecti... (Source: BMC Neuroscience)
Source: BMC Neuroscience - February 29, 2024 Category: Neuroscience Authors: Katharina Ritter, Pawit Somnuke, Lingjiao Hu, Eva-Verena Griemert and Michael K.E. Sch äfer Tags: Review Source Type: research

A flowchart for adequate controls in virus-based monosynaptic tracing experiments identified Cre-independent leakage of the TVA receptor in R ΦGT mice
A pseudotyped modified rabies virus lacking the rabies glycoprotein (G-protein), which is crucial for transsynaptic spread, can be used for monosynaptic retrograde tracing. By coupling the pseudotyped virus wi... (Source: BMC Neuroscience)
Source: BMC Neuroscience - February 21, 2024 Category: Neuroscience Authors: Anna Velica and Klas Kullander Tags: Research Source Type: research

Multimodal evaluation of the effects of low-intensity ultrasound on cerebral blood flow after traumatic brain injury in mice
Traumatic brain injury (TBI) is one of the leading causes of death and disability worldwide, and destruction of the cerebrovascular system is a major factor in the cascade of secondary injuries caused by TBI. ... (Source: BMC Neuroscience)
Source: BMC Neuroscience - February 13, 2024 Category: Neuroscience Authors: Huiling Yi, Shuo Wu, Xiaohan Wang, Lanxiang Liu, Wenzhu Wang, Yan Yu, Zihan Li, Yinglan Jin, Jian Liu, Tao Zheng and Dan Du Tags: Comment Source Type: research