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Genetic, Cellular and Molecular Aspects involved in Apical Periodontitis
Braz Dent J. 2022 Jul-Aug;33(4):1-11. doi: 10.1590/0103-6440202205113.ABSTRACTThe development, establishment and repair of apical periodontitis (AP) is dependent of several factors, which include host susceptibility, microbial infection, immune response, quality of root canal treatment and organism's ability to repair. The understanding of genetic contributions to the risk of developing AP and presenting persistent AP has been extensively explored in modern Endodontics. Thus, this article aims to provide a review of the literature regarding the biochemical mediators involved in immune response signaling, osteoclastogenesis...
Source: Braz Dent J - August 31, 2022 Category: Dentistry Authors: Igor Bassi Ferreira Petean Alice Corr ĂȘa Silva-Sousa Tamara Justiniano Cronenbold Jardel Francisco Mazzi-Chaves Lea Assed Bezerra da Silva Raquel Assed Bezerra Segato Guilherme Assed Piedade de Castro Erika Calvano Kuchler Francisco Wanderley Garcia Paul Source Type: research