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Vaccination: Whooping Cough (Pertussis) Vaccine
Nutrition: Sugar
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Total 13 results found since Jan 2013.
Development and validation of a spectrophotometric method for quantification of residual cyclodextrin (DIMEB; Heptakis) in pertussis antigens
We report here development and validation of a spectrophotometric method for estimation of DIMEB in different product matrices of pertussis vaccine antigens i.e. Filamentous haemagglutinin (FHA), Pertactin (PRN) and Pertussis toxin (PT). The detection is based on characteristic reaction of hydrolyzed sugars derivatives from DIMEB i.e., furfural derivatives with anthrone reagent to form colored complexes which could be quantified at 625 nm. Method showed excellent linearity with correlation coefficient (R2) > 0.995 over the concentration of 5.0-80.0 μg. LOD and LOQ of 1.47 μg and 4.46 μg respectively was reported. The...
Source: Biologicals : Journal of the International Association of Biological Standardization - February 15, 2023 Category: Biotechnology Authors: Bharat Shinde Dadasaheb Patil Vinod Nandre Manish Gautam Pooja Doshi Sunil Gairola Source Type: research
