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Total 6508 results found since Jan 2013.

Preclinical testing platforms for mechanical thrombectomy in stroke: a review on phantoms, in-vivo animal, and cadaveric models
This article provides a critical review of phantoms, in-vivo animal, and human cadaveric models used for thrombectomy testing and provides insights into the strengths and limitations of each platform. Articles published in the past 10 years that reported thrombectomy testing platforms were identified. Characteristics of each test platform, such as intracranial anatomy, artery tortuosity, vessel friction, flow conditions, device-vessel interaction, and visualization, were captured and benchmarked against human cerebral vessels involved in large-vessel occlusion stroke. Thrombectomy phantoms have been constructed from silico...
Source: Journal of NeuroInterventional Surgery - August 13, 2021 Category: Neurosurgery Authors: Liu, Y., Abbasi, M., Arturo Larco, J. L., Kadirvel, R., Kallmes, D. F., Brinjikji, W., Savastano, L. Tags: Ischemic stroke Source Type: research

Efficacy of beveled tip aspiration catheter in mechanical thrombectomy for acute ischemic stroke
Conclusion Patients who underwent mechanical thrombectomy with the beveled tip catheter had a higher proportion of TICI 2C or better and had a significantly lower mRS score on discharge and at 90 days.
Source: Journal of NeuroInterventional Surgery - August 13, 2021 Category: Neurosurgery Authors: Vargas, J., Blalock, J., Venkatraman, A., Anagnostakou, V., King, R. M., Ewing, J. A., Gounis, M. J., Turner, R. D., Chaudry, I., Turk, A. Tags: Open access, Ischemic stroke Source Type: research

Age-adjusted infarct volume cut-off points improve stroke outcome prognostication beyond modeling with age and infarct volume
Conclusions Age-adjusted infarct volume represents a strong outcome discriminator beyond age and infarct volume in isolation and might help to refine patient selection and improve outcome prognostication in stroke thrombectomy.
Source: Journal of NeuroInterventional Surgery - January 18, 2022 Category: Neurosurgery Authors: Bouslama, M., Haussen, D. C., Rodrigues, G. M., Barreira, C. M., Dehkharghani, S., Frankel, M. R., Nogueira, R. G. Tags: Ischemic stroke Source Type: research

POSITIVE: Perfusion imaging selection of ischemic stroke patients for endovascular therapy
Conclusion POSITIVE supports the already established practice of delayed thrombectomy for appropriately selected patients presenting within 0–12 hours selected by perfusion imaging from any vendor. The results of the POSITIVE trial are consistent with other thrombectomy trials. The statistically significant effect on functional improvement, despite the small number of patients, reinforces the robust benefits of thrombectomy. Clinical trial registration NCT01852201
Source: Journal of NeuroInterventional Surgery - January 18, 2022 Category: Neurosurgery Authors: Mocco, J., Siddiqui, A. H., Fiorella, D., Alexander, M. J., Arthur, A. S., Baxter, B. W., Budzik, R. F., Froehler, M. T., Hanel, R. A., Lena, J., Persaud, S., Puri, A. S., Rai, A. T., Wintermark, M., Woodward, K., Zhang, X., Turk, A. Tags: Ischemic stroke Source Type: research

MRS SOFIA: a multicenter retrospective study for use of Sofia for revascularization of acute ischemic stroke
Conclusion Our study highlights the potential advantage of the Sofia aspiration catheter for primary aspiration thrombectomy in acute ischemic stroke. High rates of first pass recanalization with low crossover rates to other thrombectomy devices were achieved. Median procedure time was low, as were procedural complications.
Source: Journal of NeuroInterventional Surgery - January 18, 2022 Category: Neurosurgery Authors: Brinjikji, W., Raz, E., De Leacy, R., Meila, D., Mokin, M., Samaniego, E. A., Shapiro, M., Bageac, D., Varon, A., Ren, Z., Rinaldo, L., Cloft, H. J. Tags: Ischemic stroke Source Type: research

Local anesthesia as a distinct comparator versus conscious sedation and general anesthesia in endovascular stroke treatment: a systematic review and meta-analysis
Conclusion LA without sedation was not significantly superior to CS or GA in improving outcomes when performing EVT for AIS. However, the quality of the included studies impaired interpretation, and inclusion of an LA arm in future well designed multicenter, randomized controlled trials is warranted.
Source: Journal of NeuroInterventional Surgery - February 16, 2022 Category: Neurosurgery Authors: Butt, W., Dhillon, P. S., Podlasek, A., Malik, L., Nair, S., Hewson, D., England, T. J., Lenthall, R., McConachie, N. Tags: Ischemic stroke Source Type: research

Histological evaluation of acute ischemic stroke thrombi may indicate the occurrence of vessel wall injury during mechanical thrombectomy
Conclusions Histological markers of VWI were present in 12% of AIS thrombi, suggesting that VWI might be related to MT. VWI was associated with soft thrombus consistency, higher number of passes and poorer revascularization outcome. There was no significant correlation between VWI and MT device.
Source: Journal of NeuroInterventional Surgery - March 18, 2022 Category: Neurosurgery Authors: Mereuta, O. M., Abbasi, M., Fitzgerald, S., Dai, D., Kadirvel, R., Hanel, R. A., Yoo, A. J., Almekhlafi, M. A., Layton, K. F., Delgado Almandoz, J. E., Kvamme, P., Mendes Pereira, V., Jahromi, B. S., Nogueira, R. G., Gounis, M. J., Patel, B., Aghaebrahim, Tags: Open access, Ischemic stroke Source Type: research

Histopathological analysis of retrieved thrombi from patients with acute ischemic stroke with malignant tumors
Conclusions Thromboemboli of major cerebral arteries in patients with cancer were mainly composed of fibrin/platelet-rich components.
Source: Journal of NeuroInterventional Surgery - April 12, 2022 Category: Neurosurgery Authors: Kataoka, Y., Sonoda, K., Takahashi, J. C., Ishibashi-Ueda, H., Toyoda, K., Yakushiji, Y., Kusaka, H., Koga, M. Tags: Ischemic stroke Source Type: research

Collateral status reperfusion and outcomes after endovascular therapy: insight from the Endovascular Treatment in Ischemic Stroke (ETIS) Registry
Conclusions Collateral status predicted functional outcome after EVT. However, collateral status on the pretreatment angiogram did not decrease the clinical benefit of successful reperfusion.
Source: Journal of NeuroInterventional Surgery - May 13, 2022 Category: Neurosurgery Authors: Anadani, M., Finitsis, S., Clarencon, F., Richard, S., Marnat, G., Bourcier, R., Sibon, I., Dargazanli, C., Arquizan, C., Blanc, R., Lapergue, B., Consoli, A., Eugene, F., Vannier, S., Spelle, L., Denier, C., Boulanger, M., Gauberti, M., Liebeskind, D. S. Tags: Ischemic stroke Source Type: research

Device size selection can enhance Y-stentrieving efficacy and safety as a rescue strategy in stroke thrombectomy
Conclusion Y-stentrieving is an effective and safe bail-out strategy for refractory bifurcation clots. Longer stents may promote better angiographic outcomes, whereas avoidance of disproportionately large retrievers may mitigate intracranial hemorrhage. Future studies should account for these factors when evaluating alternative stentriever techniques.
Source: Journal of NeuroInterventional Surgery - May 13, 2022 Category: Neurosurgery Authors: Cabral, L. S., MontAlverne, F., Silva, H. C., Passos Filho, P. E., Magalhaes, P. S. C., Bianchin, M. M., Nogueira, R. G. Tags: Ischemic stroke Source Type: research

General anesthesia during endovascular therapy for acute ischemic stroke: benefits beyond better reperfusion?
Conclusion The better outcome after EVT in the GA arm was mainly a direct effect—that is, an effect that was not explained by better reperfusion. We also found a better outcome in the GA arm when reperfusion was not achieved. Whether this is an effect of the stable condition and blood pressure under GA or a neuroprotective effect will need to be investigated in future research.
Source: Journal of NeuroInterventional Surgery - July 14, 2022 Category: Neurosurgery Authors: Simonsen, C. Z., Rasmussen, M., Schönenberger, S., Henden, P. L., Bösel, J., Valentin, J. B. Tags: Ischemic stroke Source Type: research

Addition of intracranial aspiration to balloon guide catheter does not improve outcomes in large vessel occlusion anterior circulation stent retriever based thrombectomy for acute stroke
Conclusions Our data showed that addition of distal intracranial aspiration catheters to BGC+SR based thrombectomy in patients with acute anterior circulation LVO did not provide higher rates of FPE or improved clinical outcomes.
Source: Journal of NeuroInterventional Surgery - August 12, 2022 Category: Neurosurgery Authors: Blasco, J., Puig, J., Lopez-Rueda, A., Daunis-i-Estadella, P., Llull, L., Zarco, F., Macias, N., Macho, J., Gonzalez, E., Labayen, I., Vega, P., Murias, E., Jimenez-Gomez, E., Bravo Rey, I., Moreu, M., Perez-Garcia, C., Chirife Chaparro, O., Aixut, S., Te Tags: Ischemic stroke Source Type: research

Non-contrast head CT alone for thrombectomy in acute ischemic stroke: analysis of the ANGEL-ACT registry
Conclusions In patients selected for MT using NCHCT alone versus NCHCT + NVI, there were improved procedural outcomes and smaller increases in baseline mRS scores at 90 days.
Source: Journal of NeuroInterventional Surgery - August 12, 2022 Category: Neurosurgery Authors: Ren, Z., Ma, G., Mokin, M., Jadhav, A. P., Jia, B., Tong, X., Bauer, C., Liu, R., Wang, A., Zhang, X., Mo, D., Ma, N., Gao, F., Song, L., Sun, X., Huo, X., Deng, Y., Liu, L., Luo, G., Luo, X., Peng, Y., Gui, L., Song, C., Wu, J., Wang, L., Li, C., Jovin, Tags: Ischemic stroke Source Type: research

Real-world outcomes associated with the use of the EmboTrap revascularization device for ischemic stroke in the United States
Conclusions This is the first study in the US to report real-world outcomes sourced by retrospective database analysis among patients with AIS undergoing MT using the EmboTrap device. Further research is needed to better understand performance of the EmboTrap device in real-world settings.
Source: Journal of NeuroInterventional Surgery - October 14, 2022 Category: Neurosurgery Authors: Brinjikji, W., Ikeme, S., Kottenmeier, E., Khaled, A., M, S., Khanna, R. Tags: Ischemic stroke Source Type: research