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Infectious Disease: Candida
Management: Hospitals

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Total 572 results found since Jan 2013.

< em > In vitro < /em > activity of sanitizers against mono- and polymicrobial biofilms of < em > C. parapsilosis < /em > and < em > S. aureus < /em >
In this study, we investigated the impact of 11 different commercial sanitizers at various concentrations and exposure times on biofilms consisting of clinical and nosocomial environmental isolates of Candida parapsilosis and Staphylococcus aureus. Among the sanitizers tested, 0.5% and 2.0% chlorhexidine (CLX), 10% polyvinyl pyrrolidone (PVP-I), a disinfectant based on quaternary ammonium compound (QAC), 2% glutaraldehyde, and 0.55% orthophthalaldehyde (OPA) demonstrated efficacy against both C. parapsilosis and S. aureus in monospecies and mixed biofilms. Analysis showed that 0.5% CLX and 10% PVP-I had fungicidal and bact...
Source: Antimicrobial Agents and Chemotherapy - September 8, 2023 Category: Microbiology Authors: Vitor de Paula Castro Danilo Yamamoto Thomaz Kayro de Lima Vieira Leonardo Guedes Lopes Flavia Rossi Gilda M B Del Negro Gil Benard Regina Helena Pires Source Type: research

Rapid Evolution of Multidrug Resistance in a Candida lusitaniae Infection during Micafungin Monotherapy
Antimicrob Agents Chemother. 2023 Jul 10:e0054323. doi: 10.1128/aac.00543-23. Online ahead of print.ABSTRACTCandida (Clavispora) lusitaniae is a rare, emerging non-albicans Candida species that can cause life-threatening invasive infections, spread within hospital settings, and rapidly acquire antifungal drug resistance, including multidrug resistance. The frequency and spectrum of mutations causing antifungal drug resistance in C. lusitaniae are poorly understood. Analyses of serial clinical isolates of any Candida species are uncommon and often analyze a limited number of samples collected over months of antifungal thera...
Source: Antimicrobial Agents and Chemotherapy - July 10, 2023 Category: Microbiology Authors: Nancy E Scott Serin Edwin Erayil Susan E Kline Anna Selmecki Source Type: research