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Source: Ontario Health Technology Assessment Series

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Pre-surgical Nasal Decolonization of < em > Staphylococcus aureus: < /em > A Health Technology Assessment
CONCLUSIONS: Based on the best evidence available, decolonization of S. aureus using nasal mupirocin combined with chlorhexidine body wash prior to cardiothoracic, vascular, orthopaedic, gastrointestinal, or general surgery lowers the incidence of surgical site infection caused by S. aureus in patients who are S. aureus carriers (including methicillin-susceptible and methicillin-resistant strains) (i.e., targeted decolonization). However, nasal mupirocin alone may result in little to no difference in overall surgical site infections and S. aureus-related surgical site infections in pre-surgical patients prior to orthopaedi...
Source: Ontario Health Technology Assessment Series - September 26, 2022 Category: General Medicine Authors: Ontario Health (Quality) Source Type: research