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Source: Ontario Health Technology Assessment Series

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Total 960 results found since Jan 2013.

Proton Beam Therapy for Cancer in Children and Adults: A Health Technology Assessment
CONCLUSIONS: Proton beam therapy may be as effective as conventional radiation therapy, and it may cause fewer side effects, especially for children with brain tumours and for adults with certain types of cancer. Based on published economic evidence, proton beam therapy is likely cost-effective compared with photon therapy in children with medulloblastoma, but cost-effectiveness is unclear in children and adults with other clinical indications. We estimate that publicly funding a proton beam therapy centre in Ontario would result in additional costs of $124.8 million over the next 5 years, but with a six- to seven-fold red...
Source: Ontario Health Technology Assessment Series - May 31, 2021 Category: General Medicine Authors: Ontario Health (Quality) Source Type: research

Pre-surgical Nasal Decolonization of < em > Staphylococcus aureus: < /em > A Health Technology Assessment
CONCLUSIONS: Based on the best evidence available, decolonization of S. aureus using nasal mupirocin combined with chlorhexidine body wash prior to cardiothoracic, vascular, orthopaedic, gastrointestinal, or general surgery lowers the incidence of surgical site infection caused by S. aureus in patients who are S. aureus carriers (including methicillin-susceptible and methicillin-resistant strains) (i.e., targeted decolonization). However, nasal mupirocin alone may result in little to no difference in overall surgical site infections and S. aureus-related surgical site infections in pre-surgical patients prior to orthopaedi...
Source: Ontario Health Technology Assessment Series - September 26, 2022 Category: General Medicine Authors: Ontario Health (Quality) Source Type: research