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E-010 Strict aspects cutoffs in endovascular therapy selection paradigms may harm patient outcomes
ConclusionASPECT scores at presentation in patients with LVO were associated with 90-day disability outcomes in a continuous fashion. In patients with ASPECTS close to 5, EST continued to provide significant treatment effect. These findings argue against the use of strict ASPECTS cutoffs for EST eligibility.Disclosures R. Abdelkhaleq: None. C. De la Garza: None. Y. Kim: None. S. Khose: None. S. Salazar Marioni: None. S. Sheth: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Abdelkhaleq, R., De la Garza, C., Kim, Y., Khose, S., Salazar Marioni, S., Sheth, S. Tags: Electronic poster abstracts Source Type: research

E-018 A comparison of two automated CTP algorithms for estimation of core infarct
ConclusionsThere was not a statistically significant difference in calculated rCBF<30% volumes between Viz or Rapid, compared to the manually segmented volumes from the 24 hour diffusion MRI.Disclosures J. Vargas: 2; C; Corindus, Medtronic, Cerenovus. 4; C; Visom, Ceretronic, Truvic. S. Moorhead: None. M. Chaudry: 2; C; Cerenovus, Medtronic, Q’Apel. 4; C; Q’Apel. R. Turner: 2; C; Siemens, Medtronic. 5; C; Siemens. A. Turk: 2; C; Siemens, Viz.AI, Medtronic. 4; C; Viz.AI.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Vargas, J., Moorhead, S., Chaudry, M., Turner, R., Turk, A. Tags: Electronic poster abstracts Source Type: research

O-067 Super large-bore ingestion of clot (SLIC) leads to high first-pass effect in thrombectomy for large vessel occlusion
ConclusionOur initial experience with the SLIC technique resulted in achieving first-pass effect (mTICI≥2C) in 70.5%. Navigation of the SLBA catheter extender over the Tenzing insert was successful and safe in this early experience.Disclosures F. Massari: None. G. Dabus: 2; C; Medtronic, Microvention, Cerenovus, Penumbra, Stryker, InNeuroCo, Route 92. G. Cortez: None. J. Singh: None. A. Kuhn: None. V. Naragum: None. V. Anagnostakou: None. R. Hanel: 1; C; NIH, Interline Endowment, Microvention, Stryker and CNX. 2; C; Medtronic, Balt, Stryker, Q’Apel medical, Codman Neuro (J&J), Cerenovus, Microvention, Imperati...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Massari, F., Dabus, G., Cortez, G., Singh, J., Kuhn, A., Naragum, V., Anagnostakou, V., Hanel, R., Gounis, M., Puri, A. Tags: SNIS 19th annual meeting oral abstracts Source Type: research

Falsely normal CT perfusion ischemic core readings are common and often associated with deep infarcts
Conclusions CTP may completely fail to detect ischemic core in as many as 25% of cases, especially in isolated deep MCA strokes. Technical refinements of the post-processing algorithms are therefore warranted. TMC infarcts may have a lower risk of reperfusion hemorrhage, potentially due to greater preservation of the neurovascular unit structure in face of delayed recovery of cerebral blood flow.
Source: Journal of NeuroInterventional Surgery - January 11, 2023 Category: Neurosurgery Authors: Bouslama, M., Ravindran, K., Rodrigues, G. M., Pisani, L., Haussen, D. C., Frankel, M. R., Nogueira, R. G. Tags: Neuroimaging Source Type: research

O10/94 Ghost infarct core phenomenon after thrombectomy is associated with higher core lesion volume and degree of reperfusion
ConclusionOverestimation of the ischemic core occurred more often in patients presenting with large ICV and was associated with better functional outcomes. Although higher core volumes were associated with worse outcomes, timely vessel recanalization may result in significant treatment effects in this subgroup of patients. Large ICVs should not implicitly exclude patients from MT.Abstract O10/94 Figure 1Abstract O10/94 Figure 2Disclosure of InterestNA.
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Broocks, G., Meyer, L., Heit, J., Fiehler, J., Faizy, T. Tags: 2.2 ISCHEMIC - Imaging Source Type: research

P-014 Improvement in Angiographic Transit Times Post Endovascular Vasospasm Treatment in Patients with Aneurysmal Subarachnoid Haemorrhage
Conclusion The DSA TT correlated with improvements in neurological status in patients with clinical vasospasm. TT might reflect a better way to assess vasospasm severity and response to treatment as compared to vessel diameter. This method may serve as a useful indirect technique for cerebral blood flow assessment in the angiography suite. Abstract P-014 Figure 1Transit time (T-100-10) in major cerebral arteries in patient with severe vasospasm before (A) and after (B) endovascular treatment Abstract P-014 Figure 2ACA and MCA transit time100-10(TT-100-10) values in patients before and after endovascular treatment D...
Source: Journal of NeuroInterventional Surgery - July 26, 2014 Category: Neurosurgery Authors: Ivanov, A., Hsu, C., Linninger, A., Amin-Hanjani, S., Aletich, V., Charbel, F., Alaraj, A. Tags: Oral poster abstracts Source Type: research

P-020 Emergent Carotid Artery Stenting with or without Intracranial Tandem Occlusion Lesions Following Carotid Endarterectomy
Conclusion Emergent endovascular evaluation in the setting of acute post CEA thrombosis is a safe and timely treatment option, with the benefit of detecting and treating embolic intracranial lesions. More investigation is necessary to define the role of immediate angiography and intervention in this rare surgical complication. Abstract P-020 Table 1Patient demographics AgeGender% Carotid stenosisSymptomaticCase 166M90NCase 273M80–99YCase 378M70YCase 459F80–99YCase 555M80–99NCase 680MUnknownUnknown Abstract P-020 Table 2Pre procedural metrics Time from CEA to symptoms (hrs)Time from last normal to throm...
Source: Journal of NeuroInterventional Surgery - July 26, 2014 Category: Neurosurgery Authors: Vargas, J., Zuckerman, S., Chaudry, I., Turner, R., Turk, A., Spiotta, A. Tags: Oral poster abstracts Source Type: research

P-016 role of balloon guiding catheter in mechanical thrombectomy using stentretrivers subgroup analysis of swift prime
ConclusionBGC use in the SWIFT PRIME cohort of patients treated with rTPA and mechanical thrombectomy with Solitaire demonstrated significantly lower infarct size and higher reperfusion rates at 27 h. Overall procedure times were shorter for BGC group. These findings suggest that there is likely benefit from use of BGC when treating AIS with mechanical thrombectomy; however, randomized trials are required to confirm this finding.Abstract P-016 Table 1Distribution of variables among BGC and no BGC group Characteristic No BGC BGC Total p-value Number394887Age (years)61.8 ± 13.566.8 ± 11.764.6 ± 12....
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Pereira, V., Siddiqui, A., Jovin, T., Yavagal, D., Levy, E., Bonafe, A., Cognard, C., Jansen, O., Nogueira, R., Jahan, R., Slater, L., Coutinho, J., Saver, J., Goyal, M. Tags: SNIS 12th Annual Meeting Oral Poster Abstracts Source Type: research

E-048 moya moya syndrome: evaluation and treatment in patients with inflammatory conditions causing a puff of smoke
ConclusionBy describing the angiographic patterns associated with Moya Moya phenomenon as well as associated symptoms we hope to elucidate the nuances of angiographic appearances in this broad clinical setting which may help narrow the differential diagnosis.. We will also discuss the treatment options and the current level of evidence for endovascular or surgical treatment.DisclosuresR. Shastri: None. N. Chaudhary: None. A. Pandey: None. C. Roark: None. B. Thompson: None. J. Gemmete: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Shastri, R., Chaudhary, N., Pandey, A., Roark, C., Thompson, B., Gemmete, J. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

E-087 negative predictive value of ct perfusion in excluding lesions amenable to endovascular reperfusion
ConclusionCTP can confidently exclude lesions which are not amenable to endovascular reperfusion.DisclosuresM. Chehab: None. J. Wilseck: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Chehab, M., Wilseck, J. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

E-139 in vivo perfusion imaging using magnetic particle imaging
ConclusionMPI shows great promise as a sensitive, high-contrast, and radiation-free technique for measuring brain perfusion, brain vasculature, and organ perfusion.AcknowledgmentsThe authors acknowledge support from the following research grants: NIH 5R01EB013689–03, CIRM RT2–01893, Keck Foundation 034317, NIH 1R24MH106053–01, NIH 1R01EB019458–01, ACTG 037829, and NIH 2R42EB013520–02A1.ReferencesWintermark M, et al. Stroke, 2005:e83Weizenecker J, et al. PMB 2009;54(5)Rahmer J, et al. PMB 2013;58(12):3965–77Saritas E, et al. JMR 2013;229:116–26Ferguson, et alet al. IEEE-TMI, in pres...
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Goodwill, P., Ferguson, M., Yu, E., Zheng, B., Lu, K., Khandhar, A., Kemp, S., Krishnan, K., Conolly, S. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

O-013 Hypertension Decreases the Number and Duration of Collateral Openings during Middle Cerebral Artery Occlusion (MCAO) and Impairs Reperfusion
ConclusionsThese results demonstrate that collateral flow during ischemia, and reperfusion, was impaired in hypertension likely due to vasoconstriction of LMAs. Understanding the function of pial collaterals under conditions such as hypertension, that is associated with little penumbral tissue, may provide targeted therapies to prevent collateral failure and extend the time window for treatment in these patients.DisclosuresM. Cipolla: 1; C; NIH grants. J. Sweet: None. K. Chan: None.
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Cipolla, M., Sweet, J., Chan, K. Tags: Oral abstracts Source Type: research

In vitro experiments of cerebral blood flow during aspiration thrombectomy: potential effects on cerebral perfusion pressure and collateral flow
Conclusions These experiments suggest that aspiration is only effective if the catheter tip is in direct contact with the thrombus. If the catheter tip is not in contact with the thrombus, aspirate is drawn from the vessels proximal of the occlusion. This could affect collateral flow in vivo.
Source: Journal of NeuroInterventional Surgery - August 11, 2016 Category: Neurosurgery Authors: Lally, F., Soorani, M., Woo, T., Nayak, S., Jadun, C., Yang, Y., McCrudden, J., Naire, S., Grunwald, I., Roffe, C. Tags: Basic science Source Type: research

P-001 Delayed enhancement ct angiography for acute thromboembolic ischemia: core infarct volume prediction and outcomes following complete mechanical thrombectomy
Conclusions CTA-SI with a delayed enhancement protocol can be used as the sole imaging technique to triage patients to endovascular therapy. While lesion volumes were not significantly similar in the recanalized group, there was no significant overestimation by the CTA-SI and thus would not be expected to exclude patients from endovascular treatment. The CTA-SI actually tended to underestimate core infarct volumes which is likely related to continued core infarct expansion during recanalization delay, as volume expansion was much greater in the nonrecanalized group, and further cytotoxic edema accumulation prior to the DWI...
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: West, J., Hise, J., Layton, K. Tags: Oral Poster Abstracts Source Type: research

E-046 Length of stay in mechanical thrombectomy, and machine learning improvement of predictive analysis
Conclusions Machine learning methods outperform multivariate logistic regression at the prediction of length of stay. Predictive analysis for patient length of stay could help hospital utilization and allow for more aggressive measures to prevent hospital acquired conditions. Disclosures S. Arndt: None. G. Bennett: None. K. Wojcik: None. A. Albar: None. M. Alhasan: None. J. Ma: None. P. Gulotta: None. J. Milburn: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Arndt, S., Bennett, G., Wojcik, K., Albar, A., Alhasan, M., Ma, J., Gulotta, P., Milburn, J. Tags: Electronic Poster Abstracts Source Type: research

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