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Source: BMJ Open

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Total 1639 results found since Jan 2013.

Risk factors for bone metastasis in patients with primary lung cancer: study protocol for a systematic review
Introduction Bone metastasis (BM) in patients with primary lung cancer poses a serious health problem. Numerous risk factors have been hypothesised to predict BM in these patients, but research studies are of mutable quality, and may not be of value in clinical evaluation. Methods and analysis We will search a number of electronic databases including PubMed, MEDLINE, Web of Science, EMBASE, the Cochrane Library (Cochrane Database of Systematic Reviews) and the Cochrane Central Register of Controlled Trials (CENTRAL). We will carry out a secondary search for articles from references of included articles (from January 1990 ...
Source: BMJ Open - July 24, 2014 Category: Journals (General) Authors: Niu, Y.-J., Wen, Y.-T., Shen, W.-W., Deng, L., Liu, L.-L., Zhang, H.-L. Tags: Open access, Evidence based practice, Oncology, Public health, Qualitative research Protocol Source Type: research

Legislative, educational, policy and other interventions targeting physicians' interaction with pharmaceutical companies: a systematic review
Conclusions Available evidence suggests a potential impact of policies aiming to reduce interaction between physicians and drug representatives on physicians’ prescription behaviour. We found no evidence concerning interventions affecting other types of interaction with pharmaceutical companies.
Source: BMJ Open - July 1, 2014 Category: Journals (General) Authors: Alkhaled, L., Kahale, L., Nass, H., Brax, H., Fadlallah, R., Badr, K., Akl, E. A. Tags: Open access, Health policy, Health services research Source Type: research

A systematic review of the influence of occupational organophosphate pesticides exposure on neurological impairment
Conclusions The findings of this literature review indicate that it is necessary to standardise the neurological or neuropsychological test battery and methods of measuring exposure to OPs.
Source: BMJ Open - June 24, 2014 Category: Journals (General) Authors: Takahashi, N., Hashizume, M. Tags: Open access, Epidemiology, Public health Research Source Type: research

Addressing the evidence to practice gap for complex interventions in primary care: a systematic review of reviews protocol
Introduction Getting the results of research implemented into routine healthcare is often a challenge. The disconnect between the development and implementation of evidence into practice is called the ‘second translational gap’ and is particularly apparent in primary care. To address this gap, we plan to identify, summarise and synthesise currently available evidence by undertaking a systematic review of reviews to: (1) explore barriers and facilitators of implementation of research evidence or complex interventions, and (2) assess the effectiveness of strategies in facilitating implementation of complex interv...
Source: BMJ Open - June 23, 2014 Category: Journals (General) Authors: Lau, R., Stevenson, F., Ong, B. N., Dziedzic, K., Eldridge, S., Everitt, H., Kennedy, A., Kontopantelis, E., Little, P., Qureshi, N., Rogers, A., Treweek, S., Peacock, R., Murray, E. Tags: Open access, Evidence based practice, General practice / Family practice, Health services research Protocol Source Type: research

Outcomes after corrective surgery for congenital dextro-transposition of the great arteries using the arterial switch technique: a protocol for a scoping systematic review
The objective of this scoping review of the literature was to document the short-term (less than 1 year), medium-term (1–20 years) and long-term (more than 20 years) outcomes in children who underwent the ASO. Our primary income is survival, but we will explore other secondary surgical, cardiovascular, reproductive and quality-of-life outcomes. Methods and analyses Using a systematic scoping review approach, we will conduct a systematic search of the published literature for experimental and observational studies published on children who received the ASO intervention for classic d-TGA. We will search...
Source: BMJ Open - June 11, 2014 Category: Journals (General) Authors: Mbuagbaw, L., Forlemu-Kamwa, D., Chu, A., Thabane, L., Dillenberg, R. Tags: Open access, Cardiovascular medicine, Paediatrics, Research methods, Surgery Protocol Source Type: research

Non-pharmacological treatments for adult patients with functional constipation: a systematic review protocol
Introduction The aim of this review is to assess the effectiveness, efficacy and safety of non-pharmacological therapies for patients with functional constipation. Methods and analysis We will electronically search OVID MEDLINE, EMBASE, Cochrane library, CINAHL, AMED and ISI web of knowledge without any language restrictions. We will also try to obtain literatures from other sources, such as a hand search of library journals or conference abstracts. After searching and screening of the studies, we will run a meta-analysis of the included randomised-controlled trials. We will summarise the results as risk ratio for dichoto...
Source: BMJ Open - June 5, 2014 Category: Journals (General) Authors: Chen, M., Zheng, H., Li, J., Huang, D., Chen, Q., Fang, J. Tags: Open access, Complementary medicine, Evidence based practice, Gastroenterology and hepatology, Medical publishing and peer review Protocol Source Type: research

Systematic review of mental health and well-being outcomes following community-based obesity prevention interventions among adolescents
Conclusions Although positive outcomes for mental health and well-being do exist, controlled evaluations of community-based obesity prevention interventions have not often included mental health measures (n=7). It is recommended that future interventions incorporate mental health and well-being measures to identify any potential mechanisms influencing adolescent weight-related outcomes, and equally to ensure interventions are not causing harm to adolescent mental health.
Source: BMJ Open - January 5, 2015 Category: Journals (General) Authors: Hoare, E., Fuller-Tyszkiewicz, M., Skouteris, H., Millar, L., Nichols, M., Allender, S. Tags: Open access, Mental health, Public health Research Source Type: research

Prevalence of tinnitus and/or hyperacusis in children and adolescents: study protocol for a systematic review
We describe the protocol of a systematic review aimed at assessing the prevalence of tinnitus and/or hyperacusis in children and young people. Methods and analysis We will include studies of any design (except case reports or case series) comparing the prevalence of tinnitus and/or hyperacusis in children and young people with and without hearing loss, any known external exposure and psychological disorders. We will search the following databases: PubMed, EMBASE and Scopus. No restrictions of language will be applied in the search strategy but during the article selection language is limited to English, German and Scandin...
Source: BMJ Open - January 5, 2015 Category: Journals (General) Authors: Nemholt, S. S., Schmidt, J. H., Wedderkopp, N., Baguley, D. M. Tags: Open access, Ear, nose and throat/otolaryngology Protocol Source Type: research

Adoption factors associated with electronic health record among long-term care facilities: a systematic review
Conclusions Similarities span the system selection phases and implementation process; of those, cost was the most common mentioned. These commonalities should help leaders in LTC facilities align strategic decisions to EHR adoption. This review may be useful for decision-makers attempting successful EHR adoption, policymakers trying to increase adoption rates without expanding incentives and vendors that produce EHRs.
Source: BMJ Open - January 28, 2015 Category: Journals (General) Authors: Kruse, C. S., Mileski, M., Alaytsev, V., Carol, E., Williams, A. Tags: Open access, Geriatric medicine, Health informatics, Health policy, Health services research Source Type: research

HIV research productivity and structural factors associated with HIV research output in European Union countries: a bibliometric analysis
Conclusions HIV research productivity varies noticeably across EU countries, and this variation is associated with recognisable structural factors.
Source: BMJ Open - February 3, 2015 Category: Journals (General) Authors: Uuskula, A., Toompere, K., Laisaar, K. T., Rosenthal, M., Purjer, M. L., Knellwolf, A., Laara, E., Des Jarlais, D. C. Tags: Open access, Epidemiology, Health informatics, HIV AIDS Research Source Type: research

Positive and negative behaviours in workplace relationships: a scoping review protocol
Introduction Engaging in teamwork requires a clear understanding of positive and negative behaviours that act as facilitators and barriers to collegial workplace relationships. Identifying and correcting underlying barriers, while promoting facilitators, is fundamental to improving care delivery and, ultimately, clinical outcomes. Despite a considerable amount of literature in this area, there is a lack of clarity of the different behaviours as several parallel literatures address similar questions about antecedents, processes and outcomes. The purpose of this study is to synthesise the current state of literature reportin...
Source: BMJ Open - February 4, 2015 Category: Journals (General) Authors: Almost, J., Wolff, A., Mildon, B., Price, S., Godfrey, C., Robinson, S., Ross-White, A., Mercado-Mallari, S. Tags: Open access, Health services research Protocol Source Type: research

A bibliometric analysis of cancer research in South Africa: study protocol
Introduction Cancer is an important and growing public health burden in South Africa (SA). Over the past few decades, there has been considerable scientific activity in cancer in SA. However, there has been limited analysis of cancer scientific publications. In this paper, we present a protocol for bibliometric analysis of cancer research conducted in SA. Methods and analysis A comprehensive search of the journal databases PubMed, SCOPUS, Web of Science and EBSCO will be conducted to identify and retrieve data from primary peer-reviewed cancer research articles using a set of consensus search words. Articles that involve ...
Source: BMJ Open - February 12, 2015 Category: Journals (General) Authors: Moodley, J., Singh, V., Kagina, B. M., Abdullahi, L., Hussey, G. D. Tags: Open access, Oncology, Public health Protocol Source Type: research

Determination of risk factors for drug-related problems: a multidisciplinary triangulation process
Conclusions The gathered risk factors may help to characterise and identify patients at risk for DRPs and may enable clinical pharmacists to guide and target preventive measures in order to limit the occurrence of DRPs. As a further step, these risk factors will serve as the basis for a screening tool to identify patients at risk for DRPs.
Source: BMJ Open - March 20, 2015 Category: Journals (General) Authors: Kaufmann, C. P., Stampfli, D., Hersberger, K. E., Lampert, M. L. Tags: Open access, Patient-centred medicine, Pharmacology and therapeutics Research Source Type: research

Educational interventions for improving control of blood pressure in patients with hypertension: a systematic review protocol
Introduction The aim of this review is to evaluate the effectiveness of educational interventions on improving the control of blood pressure in patients with hypertension. Methods Randomised controlled trials including patients over 18 years of age, regardless of sex and ethnicity, with a diagnosis of hypertension (either treated or not treated with antihypertensive medications) will be assessed in our analysis. We will electronically search four databases: MEDLINE, CINAHL, PEDro and ScienceDirect. There will be no language restrictions in the search for studies. The data will be extracted independently by two author...
Source: BMJ Open - March 31, 2015 Category: Journals (General) Authors: Ribeiro, C. D., Resqueti, V. R., Lima, I., Dias, F. A. L., Glynn, L., Fregonezi, G. A. F. Tags: Open access, Cardiovascular medicine, Rehabilitation medicine Protocol Source Type: research

Community-based physical activity interventions among women: a systematic review
Conclusions There is insufficient evidence to assess the effectiveness of community-based interventions for enhancing physical activity among women. There is a need for high-quality randomised clinical trials with adequate statistical power to determine whether multicomponent and community-based intervention programmes increase physical activity among women, as well as to determine what type of interventions have a more effective and sustainable impact on women's physical activity.
Source: BMJ Open - April 1, 2015 Category: Journals (General) Authors: Amiri Farahani, L., Asadi-Lari, M., Mohammadi, E., Parvizy, S., Haghdoost, A. A., Taghizadeh, Z. Tags: Open access, Public health, Sports and exercise medicine Research Source Type: research