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Efficacy and safety of drug therapy for the prevention and treatment of chemotherapy-induced peripheral neuropathy: a protocol for a systematic review and network meta-analysis
This article describes a protocol for evaluating the efficacy and safety of drug therapy for the prevention and treatment of CIPN. The results of the proposed systematic review with network meta-analysis (NMA) will provide new insights into the prevention and treatment of CIPN. Methods and analysis We will conduct a literature search in MEDLINE, PubMed, Embase, Cochrane Central Register of Controlled Trials and ClinicalTrials.gov to find relevant articles published through January 2023. We will include studies that investigated the efficacy and safety of vitamin B12, goshajinkigan, non-steroidal anti-inflammatory analgesi...
Source: BMJ Open - September 12, 2023 Category: General Medicine Authors: Sato, M. T., Hasegawa, T., Noma, H., Sugita, H., Ota, E. Tags: Open access, Oncology Source Type: research

Do bisphosphonates and RANKL inhibitors alter the progression of coronary artery calcification? A systematic review and meta-analysis protocol
This study does not require ethics as it is a systematic review of the literature. The results of the review described within this protocol will be distributed via presentations at relevant conferences and publication within a peer-reviewed journal. PROSPERO registration number The systematic review pertaining to this protocol is registered with PROSPERO (Registration ID: CRD42022312377).
Source: BMJ Open - October 7, 2022 Category: General Medicine Authors: Saunders, S. L., McOrist, N. S., Chaudhri, K., Gnanenthiran, S. R., Shalaby, G. Tags: Open access, Cardiovascular medicine Source Type: research

Prevalence of vitamin D and calcium deficiencies and their health impacts on women of childbearing age: a protocol for systematic review and meta-analysis
Introduction No systematic reviews has synthesised data on the available evidence to determine the prevalence of calcium and vitamin D deficiencies as a public health problem globally. Therefore, this study presents a protocol for conducting a review and meta-analysis to estimate the prevalence of calcium and vitamin D serum deficiencies in women of childbearing age and stratify these data by age group, urban and rural area, world region and pregnant/non-pregnant women whenever possible. Methods and analysis The systematic review protocol involves conducting a literature search in the following databases: PubMed, LILACS, ...
Source: BMJ Open - May 6, 2022 Category: General Medicine Authors: Silveira, E. A., Moura, L. d. A. N. e., Castro, M. C. R., Kac, G., Noll, P. R. e. S., de Oliveira, C., Noll, M. Tags: Open access, Nutrition and metabolism Source Type: research