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Diabetes drug pioglitazone could get personal: Neither panacea, nor peril
When I was in training, one of my beloved mentors declared, “I never use a drug until it’s been on the market for 20 years.” I was young enough then that I couldn’t fathom being a doctor for 20 years, let alone waiting two decades to use a new drug. As my career has progressed, I’ve seen many new drugs released to the market. Some of them are truly miraculous, bringing people longer, healthier, and more productive lives. Many of them have not withstood the test of time. More than a few have even been taken off the market. Even though the Food and Drug Administration diligently reviews each new medicine before it�...
Source: New Harvard Health Information - May 5, 2016 Category: Consumer Health News Authors: Lori Wiviott Tishler, MD, MPH Tags: Diabetes Drugs and Supplements pioglitazone thiazolidinediones Source Type: news

Only the overworked die young
Follow me at @JohnRossMD Billy Joel was on to something. As the singer-songwriter suggested in “Movin’ Out,” working too hard really can give you a “heart attack-ack-ack…” And, as a recent study has also shown, stroke may be an even bigger problem than heart attack in people who are overworked. For the study, researchers from University College London compiled data on the relationship between working hours and heart attack risk in over 600,000 workers, as well as similar data on stroke risk in over 500,000 workers. They adjusted their data to compensate for individual workers’ differences due to healt...
Source: New Harvard Health Information - December 14, 2015 Category: Consumer Health News Authors: John Ross, MD, FIDSA Tags: Behavioral Health Heart Health Hypertension and Stroke Prevention Stress overworked Source Type: news

Get the flu vaccine, reduce your risk of death
Last year was a lousy year for the flu vaccine. Hospitalizations for flu hit a nine-year high, and the vaccine prevented flu in only 23% of all recipients, compared with 50% to 60% of recipients in prior years. Why does the flu vaccine work well in some winters and not others? The flu vaccine primes the immune system to attack two proteins on the surface of the influenza A virus, hemagglutinin (H) and neuraminidase (N). Different flu strains have different combinations of these proteins — for example, the strains targeted by recent flu vaccines are H3N2 and H1N1. Unfortunately, the influenza virus is microbiology’s ans...
Source: New Harvard Health Information - September 15, 2015 Category: Consumer Health News Authors: John Ross, MD, FIDSA Tags: Cold and Flu Vaccines Flu Shot flu vaccine Source Type: news