• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

The DELTA 2 Registry: A Multicenter Registry Evaluating Percutaneous Coronary Intervention With New-Generation Drug-Eluting Stents in Patients With Obstructive Left Main Coronary Artery Disease
Conclusions After a median follow-up period of 17 months, PCI with new-generation drug-eluting stents was associated with an overall low rate of the composite endpoint of death, MI, or cerebrovascular accident.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - December 4, 2017 Category: Cardiology Authors: Chieffo, A., Tanaka, A., Giustino, G., Briede, I., Sawaya, F. J., Daemen, J., Kawamoto, H., Meliga, E., DAscenzo, F., Cerrato, E., Stefanini, G. G., Capodanno, D., Mangiameli, A., Templin, C., Erglis, A., Morice, M. C., Mehran, R., Van Mieghem, N. M., Nak Tags: Coronary: Focus on Stent Technology Source Type: research

Comparison of Stenting Versus Bypass Surgery According to the Completeness of Revascularization in Severe Coronary Artery Disease: Patient-Level Pooled Analysis of the SYNTAX, PRECOMBAT, and BEST Trials
Conclusions For the treatment of left main or multivessel coronary artery disease, PCI resulting in CR was associated with a similar long-term survival rate to CABG resulting in CR. Therefore, the ability to achieve CR should enter into the decision algorithm for choice of revascularization strategy.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - July 17, 2017 Category: Cardiology Authors: Ahn, J.-M., Park, D.-W., Lee, C. W., Chang, M., Cavalcante, R., Sotomi, Y., Onuma, Y., Tenekecioglu, E., Han, M., Lee, P. H., Kang, S.-J., Lee, S.-W., Kim, Y.-H., Park, S.-W., Serruys, P. W., Park, S.-J. Tags: Coronary Source Type: research

Comparison of Trends and In-Hospital Outcomes of Concurrent Carotid Artery Revascularization and Coronary Artery Bypass Graft Surgery: The United States Experience 2004 to 2012
Conclusions In patients with concomitant carotid and coronary disease undergoing combined revascularization, combined CEA+CABG is utilized most frequently, followed by staged CEA+CABG and staged CAS+CABG strategies. The staged CAS+CABG strategy was associated with lower risk of mortality, but higher risk of stroke. Future studies are needed to examine the risks/benefits of different carotid revascularization strategies for high-risk patients requiring concurrent CABG.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - February 5, 2017 Category: Cardiology Authors: Feldman, D. N., Swaminathan, R. V., Geleris, J. D., Okin, P., Minutello, R. M., Krishnan, U., McCormick, D. J., Bergman, G., Singh, H., Wong, S. C., Kim, L. K. Tags: CME Source Type: research

Coronary Artery Bypass Surgery Versus Drug-Eluting Stent Implantation for Left Main or Multivessel Coronary Artery Disease: A Meta-Analysis of Individual Patient Data
Conclusions CABG, as compared with PCI with DES, reduced long-term rates of the composite of all-cause death, myocardial infarction, or stroke in patients with left main or multivessel CAD. The advantage of CABG over PCI with DES was particularly pronounced in those with multivessel CAD.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - December 18, 2016 Category: Cardiology Authors: Lee, C. W., Ahn, J.-M., Cavalcante, R., Sotomi, Y., Onuma, Y., Suwannasom, P., Tenekecioglu, E., Yun, S.-C., Park, D.-W., Kang, S.-J., Lee, S.-W., Kim, Y.-H., Park, S.-W., Serruys, P. W., Park, S.-J. Tags: Coronary Source Type: research

Incidence, Characteristics, Predictors, and Outcomes of Repeat Revascularization After Percutaneous Coronary Intervention and Coronary Artery Bypass Grafting: The SYNTAX Trial at 5 Years
Conclusions Repeat revascularization rates are significantly higher after initial PCI than after initial CABG for complex coronary disease. Repeat revascularization is an independent predictor of death, stroke, and myocardial infarction for myocardial revascularization.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - December 18, 2016 Category: Cardiology Authors: Parasca, C. A., Head, S. J., Milojevic, M., Mack, M. J., Serruys, P. W., Morice, M.-C., Mohr, F. W., Feldman, T. E., Colombo, A., Dawkins, K. D., Holmes, D. R., Kappetein, P. A., SYNTAX Investigators Tags: Coronary Source Type: research

Transcatheter Aortic Valve Replacement: The New Standard in Patients With Previous Coronary Bypass Grafting?
Conclusions Since its introduction in 2007, TAVR has been increasingly used in Germany in patients with previous CABG, and in-hospital outcome data support the trend away from redo surgery.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 23, 2016 Category: Cardiology Authors: Reinöhl, J., Kaier, K., Reinecke, H., Frankenstein, L., Zirlik, A., Zehender, M., von zur Mühlen, C., Bode, C., Stachon, P. Tags: Structural Source Type: research

Long-Term Outcome of PCI Versus CABG in Insulin and Non–Insulin-Treated Diabetic Patients Results From the FREEDOM Trial
BackgroundThe prospective, randomized FREEDOM (Comparison of Two Treatments for Multivessel Coronary Artery Disease in Individuals With Diabetes) trial found coronary artery bypass graft surgery (CABG) was associated with better clinical outcomes than percutaneous coronary intervention (PCI) in patients with diabetes and multivessel disease, managed with or without insulin.ObjectivesIn this subgroup analysis of the FREEDOM trial, we examined the association of long-term clinical outcomes after revascularization in patients with insulin-treated diabetes mellitus (ITDM) compared with patients not treated with insulin.Method...
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - September 15, 2014 Category: Cardiology Source Type: research

Revascularization Strategies in Patients With Combined Carotid and Coronary Artery Disease
Shishehbor et al. (1) retrospectively compared 3 different approaches to carotid revascularization and open heart surgery (OHS) (coronary artery bypass graft in>80% of cases) analyzing the results obtained in 350 patients treated in a tertiary US center during a 12-year period. Their results revealed that staged carotid artery stenting (CAS)-OHS and combined carotid endarterectomy (CEA)-OHS are associated with better outcomes (a composite of death, stroke, or myocardial infarction) than staged CEA-OHS at 30 days. However, the outcomes were in favor of staged CAS-OHS after the first year. The authors concluded that staged ...
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - June 16, 2014 Category: Cardiology Source Type: research

Vorapaxar in Acute Coronary Syndrome Patients Undergoing Coronary Artery Bypass Graft Surgery Subgroup Analysis From the TRACER Trial (Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome)
ConclusionsIn non–ST-segment elevation acute coronary syndrome patients undergoing CABG, vorapaxar was associated with a significant reduction in ischemic events and no significant increase in major CABG-related bleeding. These data show promise for protease-activated receptor 1 antagonism in patients undergoing CABG and warrant confirmatory evidence in randomized trials. (Trial to Assess the Effects of SCH 530348 in Preventing Heart Attack and Stroke in Patients With Acute Coronary Syndrome [TRA·CER] [Study P04736AM3]; NCT00527943)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - March 17, 2014 Category: Cardiology Source Type: research

Procedural Volume and Outcomes With Radial or Femoral Access for Coronary Angiography and Intervention
ConclusionsProcedural volume and expertise are important, particularly for radial percutaneous coronary intervention. (A Trial of Trans-radial Versus Trans-femoral Percutaneous Coronary Intervention [PCI] Access Site Approach in Patients With Unstable Angina or Myocardial Infarction Managed With an Invasive Strategy [RIVAL]; NCT01014273)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - March 10, 2014 Category: Cardiology Source Type: research

Rivaroxaban in Patients Stabilized After a ST-Segment Elevation Myocardial Infarction Results From the ATLAS ACS-2–TIMI-51 Trial (Anti-Xa Therapy to Lower Cardiovascular Events in Addition to Standard Therapy in Subjects with Acute Coronary Syndrome–Thrombolysis In Myocardial Infarction-51)
ObjectivesThe present analysis reports on the pre-specified subgroup of ST-elevation myocardial infarction (STEMI) patients, in whom anticoagulant therapy has been of particular interest.BackgroundIn ATLAS ACS-2–TIMI-51 (Anti-Xa Therapy to Lower Cardiovascular Events in Addition to Standard Therapy in Subjects with Acute Coronary Syndrome–Thrombolysis In Myocardial Infarction-51), rivaroxaban reduced cardiovascular events across the spectrum of acute coronary syndrome (ACS).MethodsSeven thousand eight hundred seventeen patients in ATLAS ACS-2-TIMI 51 presented with a STEMI. After being stabilized (1 to 7 days), they un...
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - April 29, 2013 Category: Cardiology Source Type: research

Percutaneous Coronary Intervention Versus Coronary Bypass Surgery in United States Veterans With Diabetes
ConclusionsThis study was severely underpowered for its primary endpoint, and therefore no firm conclusions about the comparative effectiveness of CABG and PCI are possible. There were interesting differences in the components of the primary endpoint. However, the confidence intervals are very large, and the findings must be viewed as hypothesis generating only. (Coronary Artery Revascularization in Diabetes; NCT00326196)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - February 18, 2013 Category: Cardiology Source Type: research