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Source: Sub-Cellular Biochemistry
Therapy: Cancer Therapy
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Total 268 results found since Jan 2013.
Modulation of DNA/RNA Methylation by Small-Molecule Modulators and Their Implications in Cancer
Subcell Biochem. 2022;100:557-579. doi: 10.1007/978-3-031-07634-3_17.ABSTRACTChromatin is an organized complex of DNA, histone proteins, and RNA. Chromatin modifications include DNA methylation, RNA methylation, and histone acetylation and methylation. The methylation of chromatin complexes predominantly alters the regulation of gene expression, and its deregulation is associated with several human diseases including cancer. Cancer is a disease characterized by dynamic changes in the genetic and epigenetic architecture of a cell. Altered DNA methylation by DNA methyltransferases (DNMTs) and m6A RNA methylation facilitate t...
Source: Sub-Cellular Biochemistry - October 27, 2022 Category: Biochemistry Authors: Ayushi Verma Abhipsa Sinha Dipak Datta Source Type: research
