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Source: Cancer Journal
Vaccination: Cancer Vaccines
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Total 234 results found since Jan 2013.
Human Papillomavirus-Directed Therapeutics for Human Papillomavirus-Associated Oropharyngeal Cancer
Cancer J. 2022 Sep-Oct 01;28(5):407-415. doi: 10.1097/PPO.0000000000000621.ABSTRACTDespite the availability of prophylactic human papillomavirus (HPV) vaccines, there is a growing incidence of HPV-associated head and neck squamous cell carcinomas (HPV-HNSCC) worldwide. The viral etiology of HPV-HNSCC provides an opportunity to develop personalized immune-based therapies, which target the unique viral- or tumor-specific proteins. Novel HPV-targeted immunotherapeutic approaches in clinical development are reviewed. Early results from these trials highlight new opportunities and potential challenges ahead. Immunotherapies for...
Source: Cancer Journal - September 27, 2022 Category: Cancer & Oncology Authors: Jean S Campbell Sara I Pai Source Type: research
Insights for Oncology Trials Garnered From the Rapid Development of an mRNA COVID-19 Vaccine
Cancer J. 2022 Mar-Apr 01;28(2):146-150. doi: 10.1097/PPO.0000000000000587.ABSTRACTThe sudden emergence of the coronavirus disease 2019 (COVID-19) pandemic in early 2020 stimulated unprecedented scientific initiatives to rapidly develop effective treatments and vaccines. One example was the development of vaccines based on messenger RNA platforms, which received emergency use authorization in the United States less than 1 year after the primary sequence of the severe acute respiratory syndrome coronavirus 2 virus was published. Novel practices arose from the collaborative efforts and inclusive clinical studies that facilit...
Source: Cancer Journal - March 25, 2022 Category: Cancer & Oncology Authors: Randall N Hyer Source Type: research
