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Source: Annual Review of Pathology
Vaccination: Cancer Vaccines

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Cutaneous Squamous Cell Carcinoma: The Frontier of Cancer Immunoprevention
Annu Rev Pathol. 2022 Jan 24;17:101-119. doi: 10.1146/annurev-pathol-042320-120056.ABSTRACTCutaneous squamous cell carcinoma (cSCC) is the second most common cancer, with its incidence rising steeply. Immunosuppression is a well-established risk factor for cSCC, and this risk factor highlights the critical role of the immune system in regulating cSCC development and progression. Further highlighting the nature of cSCC as an immunological disorder, substantial evidence demonstrates a tight association between cSCC risk and age-related immunosenescence. Besides the proven efficacy of immune checkpoint blockade therapy for ad...
Source: Annual Review of Pathology - January 24, 2022 Category: Pathology Authors: Michael S Chang Marjan Azin Shadmehr Demehri Source Type: research