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Source: Neurocritical Care

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Total 235 results found since Jan 2013.

Intensive Care Unit Admission for Patients in the INTERACT2 ICH Blood Pressure Treatment Trial: Characteristics, Predictors, and Outcomes
ConclusionsThis study presents prognostic variables for ICU management and outcome of ICH patients included in a large international cohort. These data may assist in the selection and counseling of patients and families concerning ICU admission.
Source: Neurocritical Care - December 19, 2016 Category: Neurology Source Type: research

Physiological Effects of Early Incremental Mobilization of a Patient with Acute Intracerebral and Intraventricular Hemorrhage Requiring Dual External Ventricular Drainage
Conclusion Progressive, device-assisted early mobilization was feasible and safe in this critically ill patient with hemorrhagic stroke when titrated by an interdisciplinary team of skilled healthcare professionals. Studies are needed to gain insight into the hemodynamic and neurophysiological responses associated with early mobility in acute stroke to identify subsets of patients who are most likely to benefit from this intervention.
Source: Neurocritical Care - February 26, 2017 Category: Neurology Source Type: research

Impact of Fever Prevention in Brain-Injured Patients (INTREPID): Study Protocol for a Randomized Controlled Trial
DiscussionThe INTREPID trial will provide the first results of the impact of a pivotal fever prevention intervention in patients with acute stroke (www.clinicaltrials.gov; NCT02996266; registered prospectively 05DEC2016).
Source: Neurocritical Care - March 24, 2021 Category: Neurology Source Type: research

Influence of Patient-Specific Covariates on Test Validity of Two Delirium Screening Instruments in Neurocritical Care Patients (DEMON-ICU)
ConclusionsThe CAM-ICU and ICDSC perform well in patients requiring neurocritical care, regardless of the presence of acute stroke, TIA, or neurosurgical interventions. Yet, even very light or moderate sedation can significantly impair DSI performance.
Source: Neurocritical Care - August 9, 2021 Category: Neurology Source Type: research

Rate of Infarct –Edema Growth on CT Predicts Need for Surgical Intervention and Clinical Outcome in Patients with Cerebellar Infarction
ConclusionsEarly infarct –edema growth rate, measured via ABC/2, is a promising biomarker for identifying the need for surgical intervention in patients with acute cerebellar infarction. Additionally, it may be used to facilitate discussions regarding patient prognosis.
Source: Neurocritical Care - December 29, 2021 Category: Neurology Source Type: research

Efficacy of Early Intensive Blood Pressure Management After Thrombectomy: Protocol for a Randomized Controlled Clinical Trial (IDENTIFY)
AbstractBackgroundThe optimal strategy for blood pressure management after thrombectomy remains unknown. The primary objective  of The Early Intensive Blood Pressure Management after Endovascular Thrombectomy (IDENTIFY) study is to explore the efficacy and safety of early intensive blood pressure management strategies after thrombectomy compared with that of standard management.MethodsThe IDENTIFY study is a prospective, randomized, open-label, assessor-blinded multicenter clinical trial. Patients with acute anterior circulation ischaemic stroke who underwent endovascular thrombectomy within 6  h of stroke onset, ach...
Source: Neurocritical Care - November 3, 2022 Category: Neurology Source Type: research

Neuromonitoring in Children with Cerebrovascular Disorders
ConclusionsOur understanding of pediatric cerebrovascular disorders has increased dramatically over the past several years, in part due to advances in the neuromonitoring modalities that allow us to better understand these conditions. We are now poised, as a field, to take advantage of advances in neuromonitoring capabilities to determine how best to manage and treat acute cerebrovascular disorders in children.
Source: Neurocritical Care - February 24, 2023 Category: Neurology Source Type: research

Characteristics and Outcomes of Children with Cerebral Sinus Venous Thrombosis
ConclusionsCSVT, which has a U-shaped age distribution, is an uncommon condition in children. Stroke is common in children with CSVT, and it is associated with an increased need for mechanical ventilation and increased mortality. The need for mechanical ventilation is more common in infants, and it is associated with increased mortality across all age groups.
Source: Neurocritical Care - July 12, 2023 Category: Neurology Source Type: research

Pediatric Moyamoya Revascularization Perioperative Care: A Modified Delphi Study
ConclusionsIn the absence of data supporting specific care practices before and after indirect revascularization surgery in children with moyamoya, this Delphi process defined areas of consensus among neurosurgeons, neurologists, and intensivists with moyamoya expertise. Research priorities identified include determining the role of continuous electroencephalography in postoperative moyamoya care, optimal perioperative blood pressure and hemoglobin targets, and the role of supplemental oxygen for treatment of suspected postoperative ischemia.
Source: Neurocritical Care - July 20, 2023 Category: Neurology Source Type: research

Neurophysiologic Features Reflecting Brain Injury During Pediatric ECMO Support
ConclusionsIncreased seizure burden and increased interhemispheric differences in both quantitative electroencephalographic amplitude and TCD MCA TIBI scores are independently associated with acute brain injury in children undergoing ECMO support.
Source: Neurocritical Care - September 11, 2023 Category: Neurology Source Type: research

Minimally Invasive Endoscopic Surgery for Treatment of Spontaneous Intracerebral Hematomas: A Single-Center Analysis
Conclusions This European surgical stroke center series of an endoscopic operative technique demonstrates safety and efficacy with regard to reduction of hematoma size in patients with large and space-occupying spontaneous ICH. The study suggests that low mortality and acceptable outcomes may be achievable by minimally invasive hematoma surgery. Whether this technique reduces long-term morbidity compared to standard treatment needs to be further investigated in larger prospective randomized controlled trials.
Source: Neurocritical Care - November 10, 2014 Category: Neurology Source Type: research

Long-Term Outcome and Quality of Life After Craniectomy in Speech-Dominant Swollen Middle Cerebral Artery Infarction
Conclusions There was no statistical or clinical difference in functional outcome and quality of life in patients with speech-dominant compared to non-dominant side infarction. The side affected should not influence suitability for decompressive craniectomy.
Source: Neurocritical Care - January 29, 2015 Category: Neurology Source Type: research

Hemorrhage or Ischemia? The Importance of ‘Spotting’ it Right
Conclusion In this case of embolic ischemic stroke with reperfusion hemorrhage, contrast extravasation “spot sign” was associated with hematoma expansion.
Source: Neurocritical Care - February 4, 2015 Category: Neurology Source Type: research

CSF Volumetric Analysis for Quantification of Cerebral Edema After Hemispheric Infarction
Conclusions Volumetric CSF analysis reliably quantifies CED and distinguishes those with malignant edema and MLS from those with a more benign course after LHI. ∆CSF may provide an earlier and more sensitive indicator of edema severity across a broader dynamic range than MLS.
Source: Neurocritical Care - October 5, 2015 Category: Neurology Source Type: research

Heart-Shaped Bilateral Medullary Pyramidal Infarction as a Pathognomonic Finding of Anterior Spinal Artery Occlusion
ConclusionAcute BMP infarction may present with flaccid tetraplegia mimicking neuromuscular disorders. When the infarction is recognized early, intravenous thrombolysis can be considered to reduce morbidity of this rare stroke subtype.
Source: Neurocritical Care - May 8, 2017 Category: Neurology Source Type: research