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Source: Neurocritical Care

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Total 235 results found since Jan 2013.

Comparison of 8 Scores for predicting Symptomatic Intracerebral Hemorrhage after IV Thrombolysis
Conclusions Three scores showed good agreement with sICH: DRAGON, Stroke-TPI, and HAT with odds ratios substantially greater than 1. Stroke-TPI and HAT additionally benefited from low computational complexity and therefore performed best overall. Our results demonstrate the utility of clinical scores as predictors of sICH in acute ischemic stroke patients undergoing IV thrombolytic therapy.
Source: Neurocritical Care - March 18, 2015 Category: Neurology Source Type: research

Effects of Early Bedside Cycle Exercise on Intracranial Pressure and Systemic Hemodynamics in Critically Ill Patients in a Neurointensive Care Unit
Conclusion Early implemented exercise with a bedside cycle ergometer, for patients with severe brain injuries or stroke when admitted to a NICU, is considered to be a clinically safe procedure.
Source: Neurocritical Care - May 22, 2016 Category: Neurology Source Type: research

Comparison of Outcomes After Treatment of Large Vessel Occlusion in a Critical Care Resuscitation Unit or a Neurocritical Care Unit
ConclusionThe CCRU increased AIS-LVO patients ’ access to definitive care and reduced their transfer time from outlying medical facilities while achieving outcomes similar to those attained by patients treated in the subspecialty NCCU. We conclude that a resuscitation unit can complement the NCCU to care for patients in the hyperacute phase o f AIS-LVO.
Source: Neurocritical Care - August 25, 2019 Category: Neurology Source Type: research

The Routine Follow-up Head CT: Is it Still a Necessary Step in the Thrombolysis Pathway?
ConclusionsThe 24-h head CT scan does not change management for most patients, particularly those with low National Institutes of Health Stroke Scale scores who do not undergo MT. Consideration should be given to removing routine follow-up imaging from postthrombolysis protocols in favor of an examination-based approach.
Source: Neurocritical Care - September 27, 2021 Category: Neurology Source Type: research

Timely and Appropriate Administration of Inhaled Argon Provides Better Outcomes for tMCAO Mice: A Controlled, Randomized, and Double-Blind Animal Study
ConclusionsTimely iAr administration during ischemia showed optimal neurological outcomes and minimal infarct volumes. Moreover, an appropriate duration of argon administration was important for better neuroprotective efficacy. These findings may provide vital guidance for using argon as a neuroprotective agent and moving to clinical trials in acute ischemic stroke.
Source: Neurocritical Care - February 8, 2022 Category: Neurology Source Type: research

Incidence and Outcome of Vertebral Artery Dissection in Trauma Setting: Analysis of National Trauma Data Base
Conclusion Although infrequent, VAD in head and neck trauma is associated with higher rates of in-hospital stroke and longer length of ICU stay and total hospital stay. Early diagnosis and endovascular treatment may be an alternative option to reduce the rate of in-hospital stroke in these patients.
Source: Neurocritical Care - October 1, 2014 Category: Neurology Source Type: research

Factors Associated with the Outcome of Very Elderly Patients with Large Hemispheric Infarction Treated with Medical Management Only
ConclusionTen percent of medically managed patients ( ≥ 70 years of age) with LHI can go home or to assisted living, but with a mRS of 4. Whether this is an acceptable outcome must be individualized on a case-by-case basis; however, poor prognosis should not be automatically presumed solely based on the combination of older age and a large stroke.
Source: Neurocritical Care - January 3, 2018 Category: Neurology Source Type: research

Causes, Predictors, and Timing of Early Neurological Deterioration and Symptomatic Intracranial Hemorrhage After Administration of IV tPA
ConclusionsIn this study, only a small proportion suffered from either sICH and/or END, typically within 12  h of tPA administration. These findings may support earlier deescalation of higher acuity monitoring in clinically stable post-IV tPA patients without large vessel occlusion.
Source: Neurocritical Care - July 6, 2021 Category: Neurology Source Type: research

Impact of Cerebral Autoregulation Monitoring in Cerebrovascular Disease: A Systematic Review
AbstractCerebral autoregulation (CA) prevents brain injury by maintaining a relatively constant cerebral blood flow despite fluctuations in cerebral perfusion pressure. This process is disrupted consequent to various neurologic pathologic processes, which may result in worsening neurologic outcomes. Herein, we aim to highlight evidence describing CA changes and the impact of CA monitoring in patients with cerebrovascular disease, including ischemic stroke, intracerebral hemorrhage (ICH), and aneurysmal subarachnoid hemorrhage (aSAH). The study was preformed according to the Preferred Reporting Items for Systematic Reviews ...
Source: Neurocritical Care - April 5, 2022 Category: Neurology Source Type: research

Cohort-Based Identification of Predictors of Symptomatic Intracerebral Hemorrhage After IV Thrombolysis
Conclusions Using a novel cohort-based approach, we identified two new independent predictors of sICH after IV rt-PA therapy: the presence of the hyperdense MCA sign and early CT hypodensities. Novel methods are needed to reduce the risk of sICH for patients receiving antithrombolytic therapy for ischemic stroke.
Source: Neurocritical Care - February 18, 2015 Category: Neurology Source Type: research

TURN: A Simple Predictor of Symptomatic Intracerebral Hemorrhage After IV Thrombolysis
Conclusions We developed a new score for predicting sICH after IV thrombolysis. Our score is simple and with acceptable accuracy, making it ideal for use in the hyperacute stroke setting.
Source: Neurocritical Care - April 13, 2015 Category: Neurology Source Type: research

The SETscore to Predict Tracheostomy Need in Cerebrovascular Neurocritical Care Patients
Conclusions Based on this monocentric study, the SETscore seems to be a valid tool to indicate prolonged NICU-LOS and VT, as well as TT need in cerebrovascular NICU patients. Confirmation of these results in larger cohorts with various settings may help to develop the SETscore as a decisive tool on primary TT early in time to avoid extubation failure.
Source: Neurocritical Care - February 2, 2016 Category: Neurology Source Type: research

Predictors of Extubation Success in Patients with Posterior Fossa Strokes
Conclusions In posterior fossa stroke patients with a GCS ≤ 6 at the time of intubation and who remain intubated for more than 1 week, extubation is less likely to be successful, and tracheostomy should be considered.
Source: Neurocritical Care - February 17, 2016 Category: Neurology Source Type: research

Attitudes of Patients and Relatives Toward Disability and Treatment in Malignant MCA Infarction
ConclusionIn Germany, there is substantial heterogeneity in patients and relatives regarding acceptable disability, aphasia, and treatment decision in the hypothetical case of MMI. Relatives significantly overestimate the degree of disability that is acceptable to stroke patients. Further studies are warranted to determine whether differences in attitudes impact on the decision to undergo DHC.
Source: Neurocritical Care - December 12, 2016 Category: Neurology Source Type: research