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Source: Neurocritical Care
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Total 235 results found since Jan 2013.
Transient Hypoperfusion to Ischemic/Anoxic Spreading Depolarization is Related to Autoregulatory Failure in the Rat Cerebral Cortex
ConclusionsWe propose that the dysfunction of cerebrovascular autoregulation that occurs simultaneously with hypotension transients poses a substantial risk of SD occurrence and is not a consequence of SD. Under such circumstances, the evolving SD is not accompanied by any recognizable CBF response, which indicates a severely damaged neurovascular coupling.
Source: Neurocritical Care - December 2, 2021 Category: Neurology Source Type: research
Correction to: Early Prediction of Malignant Edema After Successful Recanalization in Patients with Acute Ischemic Stroke
Source: Neurocritical Care - January 11, 2022 Category: Neurology Source Type: research
Ferrostatin-1 Polarizes Microglial Cells Toward M2 Phenotype to Alleviate Inflammation After Intracerebral Hemorrhage
ConclusionsOverall, our findings suggest that Fer-1 may be a novel mechanism underlying microglial M2 polarization and inflammation after ICH.
Source: Neurocritical Care - January 31, 2022 Category: Neurology Source Type: research
Questioning Glutamate Excitotoxicity in Acute Brain Damage: The Importance of Spreading Depolarization
ConclusionsSpreading depolarizations better account for the acute neuronal injury arising from brain ischemia than does the early and excessive release of glutamate.
Source: Neurocritical Care - February 22, 2022 Category: Neurology Source Type: research
Ultrasound Perfusion Imaging for the Detection of Cerebral Hypoperfusion After Aneurysmal Subarachnoid Hemorrhage
ConclusionsUPI is feasible to enable detection of cerebral tissue hypoperfusion after aSAH, and the left –right difference of TTP values is the most indicative result of this finding.
Source: Neurocritical Care - February 24, 2022 Category: Neurology Source Type: research
Questioning Glutamate Excitotoxicity in Acute Brain Damage: The Importance of Spreading Depolarization
ConclusionsSpreading depolarizations better account for the acute neuronal injury arising from brain ischemia than does the early and excessive release of glutamate.
Source: Neurocritical Care - February 22, 2022 Category: Neurology Source Type: research
Correction to: Relationship Between Body Temperature and Early Neurological Deterioration after Endovascular Thrombectomy for Acute Ischemic Stroke with Large Vessel Occlusion
Source: Neurocritical Care - March 5, 2022 Category: Neurology Source Type: research
The Critical Role of Spreading Depolarizations in Early Brain Injury: Consensus and Contention
ConclusionsFinally, we summarize points of consensus and contention among the authors as well as where SD research may be heading. In an accompanying review, we critique the role of the glutamate excitotoxicity theory, how it has shaped SD research, and its questionable importance to the study of early brain injury as compared with SD theory.
Source: Neurocritical Care - March 7, 2022 Category: Neurology Source Type: research
Prognosis Predictions by Families, Physicians, and Nurses of Patients with Severe Acute Brain Injury: Agreement and Accuracy
ConclusionsFor patients with SABI, agreement in predictions between families, physicians, and nurses regarding likelihood of recovery is poor. Accuracy appears higher for physicians and nurses compared with families, with no significant difference between physicians and nurses.
Source: Neurocritical Care - April 26, 2022 Category: Neurology Source Type: research
The Spot Sign and Intraventricular Hemorrhage are Associated with Baseline Coagulopathy and Outcome in Intracerebral Hemorrhage
ConclusionsThe spot sign and IVH are associated with specific hematoma characteristics, such as size and location, but are related differently to coagulation status and clinical course. A combined analysis of the spot sign and IVH can improve the understanding of pathophysiology and risk stratification after ICH.
Source: Neurocritical Care - June 28, 2022 Category: Neurology Source Type: research
Weaning Outcomes in Patients with Brain Injury
ConclusionsPatients with acute brain injury, compared with patients without brain injury, present higher odds of undergoing unplanned extubated after weaning was started, lower odds of being extubated after the first attempt, and a higher risk of reintubation.
Source: Neurocritical Care - September 1, 2022 Category: Neurology Source Type: research
Emergency Bedside Catheter Evacuation of Deep Ganglionic Hematoma Following Recanalization Therapy in Ischemic Stroke
Source: Neurocritical Care - September 7, 2022 Category: Neurology Source Type: research
Association Between Hyperacute Blood Pressure Variability and Hematoma Expansion After Intracerebral Hemorrhage: Secondary Analysis of the FAST-MAG Database
ConclusionsHigher BPV was not found to be associated with occurrence of HE in the hyperacute or the acute period of spontaneous ICH. Further study is needed to determine the relationship.
Source: Neurocritical Care - December 5, 2022 Category: Neurology Source Type: research
Risk Factors for Anticoagulant-Associated Intracranial Hemorrhage: A Systematic Review and Meta-analysis
Conclusions This study informs risk prediction for anticoagulant-associated intracranial hemorrhage and informs guidelines for intracranial hemorrhage prevention and future research.
Source: Neurocritical Care - January 20, 2023 Category: Neurology Source Type: research
