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Source: Neurocritical Care

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Total 235 results found since Jan 2013.

Sonographic Demonstration of a Perfusion-Dependent Stroke with Negative MRI and a Flow-Limiting Stenosis
Source: Neurocritical Care - October 28, 2019 Category: Neurology Source Type: research

Risk Factors for Dysphagia and the Impact on Outcome After Spontaneous Subarachnoid Hemorrhage
ConclusionsDysphagia is a frequent complication of non-traumatic SAH and associated with poor functional outcome, infectious complications, and prolonged stay in the intensive care unit. Early identification of high-risk patients is needed to timely stratify individual patients for dysphagia treatment.
Source: Neurocritical Care - November 14, 2019 Category: Neurology Source Type: research

Serum Caspase-3 Levels and Early Mortality of Patients with Malignant Middle Cerebral Artery Infarction
ConclusionsThe novel and more important findings of our study were that high serum caspase-3 levels were associated with mortality in MMCAI patients.
Source: Neurocritical Care - November 21, 2019 Category: Neurology Source Type: research

Prevalence, Clinical Characteristics, and Outcomes Related to Ventilator-Associated Events in Neurocritically Ill Patients
ConclusionsVAE are prevalent in the neurocritically ill. They result in an increased duration of mechanical ventilation and ICU length of stay, but may not be associated with in-hospital mortality or discharge to home.
Source: Neurocritical Care - January 22, 2020 Category: Neurology Source Type: research

Beta-Blockade in Aneurysmal Subarachnoid Hemorrhage: a Systematic Review and Meta-Analysis
ConclusionsIn adult patients with aSAH, beta-blocker therapy is associated with a mortality benefit. Studies are generally of a low quality with considerable clinical heterogeneity. Prospective large interventional trials with patient centered outcomes are required to validate this finding.
Source: Neurocritical Care - January 27, 2020 Category: Neurology Source Type: research

Relationship of White Matter Lesions with Intracerebral Hemorrhage Expansion and Functional Outcome: MISTIE II and CLEAR III
ConclusionsConcomitant WML does not increase the odds for HE in patients with ICH but increases the odds for poor functional outcome.Clinical Trial Registrationhttp://www.clinicaltrials.gov trial-identifiers: NCT00224770 and NCT00784134.
Source: Neurocritical Care - February 4, 2020 Category: Neurology Source Type: research

Predicting Malignant Cerebral Edema After Large Hemispheric Stroke
Source: Neurocritical Care - January 31, 2020 Category: Neurology Source Type: research

Neurological Pupil Index as an Indicator of Neurological Worsening in Large Hemispheric Strokes
ConclusionsQuantitative monitoring of the pupillary response using an automated pupillometer could be a useful and noninvasive tool for detecting neurological deterioration due to cerebral edema in large hemispheric stroke patients.
Source: Neurocritical Care - February 23, 2020 Category: Neurology Source Type: research

Serum Glial Fibrillary Acidic Protein in Acute Stroke
Source: Neurocritical Care - March 4, 2020 Category: Neurology Source Type: research

A Pilot Study of Pharyngeal Electrical Stimulation for Orally Intubated ICU Patients with Dysphagia
ConclusionAlthough limited by its small size and non-blinded design, this is the first study demonstrating the benefits of PES in ICU patients still orally intubated, thus offering a potential new method to reduce morbidity, mortality, and economic burden in a mixed ICU population. In order to further investigate and strengthen our findings, a statistically powered, randomized controlled study is recommended.
Source: Neurocritical Care - March 19, 2020 Category: Neurology Source Type: research

What is the Role of Continuous Electroencephalography in Acute Ischemic Stroke and the Relevance of the “Ictal-Interictal Continuum”?
Source: Neurocritical Care - April 2, 2020 Category: Neurology Source Type: research

The PET Sandwich: Using Serial FDG-PET Scans with Interval Burst Suppression to Assess Ictal Components of Disease
ConclusionsIn appropriately selected patients, FDG-PET scans while in burst suppression may help dissect the underlying pathophysiologic cause of IIC findings observed on EEG and guide tailored therapy.
Source: Neurocritical Care - April 5, 2020 Category: Neurology Source Type: research

Guidelines for the Acute Treatment of Cerebral Edema in Neurocritical Care Patients
ConclusionThe available evidence suggests hyperosmolar therapy may be helpful in reducing ICP elevations or cerebral edema in patients with SAH, TBI, AIS, ICH, and HE, although neurological outcomes do not appear to be affected. Corticosteroids appear to be helpful in reducing cerebral edema in patients with bacterial meningitis, but not ICH. Differences in therapeutic response and safety may exist between HTS and mannitol. The use of these agents in these critical clinical situations merits close monitoring for adverse effects. There is a dire need for high-quality research to better inform clinicians of the best options ...
Source: Neurocritical Care - May 14, 2020 Category: Neurology Source Type: research

Efficacy of 4-Factor Prothrombin Complex Concentrates in Factor Xa Inhibitor-Associated Intracranial Bleeding
Conclusion4FPCC appears to be an effective and safe option for FXaI-associated ICB with outcomes comparable to andexanet alfa. A formal prospective evaluation of this strategy versus andexanet alpha including cost analysis is warranted.
Source: Neurocritical Care - May 18, 2020 Category: Neurology Source Type: research

Regular-Shaped Hematomas Predict a Favorable Outcome in Patients with Hypertensive Intracerebral Hemorrhage Following Stereotactic Minimally Invasive Surgery
ConclusionsPatients with regular-shaped hematomas exhibited more favorable outcomes. Irregular-shaped hematomas and postoperative residual hematoma volume predicted a poor outcome in patients with ICH following sMIS.
Source: Neurocritical Care - May 26, 2020 Category: Neurology Source Type: research