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Source: Brain and Development

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Total 35 results found since Jan 2013.

Arterial ischemic stroke and hemorrhagic stroke in Chinese children: A retrospective analysis
This study retrospectively reviewed the records of all patients in both department of neurology and department of neurosurgery in Children’s hospital of Chongqing medical university from January 2003 to March 2011, and patients were eligible for analysis if they had been diagnosed with AIS or HS. And SPSS 17.0 software was used for statistical analysis. The χ2 test was used to exam relationships between stroke types and sex, age, and that between neuroradiological images and sex. 119 Boys (70.4%) and 50 girls (29.6%) were included. In these cases, HS accounted for the majority of the cases (n=109, 64.1%), and vitamin K ...
Source: Brain and Development - March 4, 2013 Category: Neurology Authors: Ling-ling Xie, Li Jiang Tags: Original articles Source Type: research

Improvement in a post-stroke pediatric patient with hemiplegia: Use of a hand-arm bimanual intensive therapy with hybrid assistive limb
We report a case of pediatric stroke in the chronic phase, in which a combination of novel treatments resulted in a significant improvement in physical function.
Source: Brain and Development - August 29, 2023 Category: Neurology Authors: Yoko Matsumoto, Yuji Yoshii, Akiyo Ikutomo, Mariko Yagi, Mio Nishimura, Yoko Kawasaki, Amanda Sarafian, Heakyung Kim, David P. Roye, Hiroko Matsumoto Tags: Case Report Source Type: research

Perfusion status of the stroke-like lesion at the hyperacute stage in MELAS
Abstract: Hypoperfusion on single-photon emission computed tomography (SPECT) of the stroke-like lesion (SLL) at the hyperacute stage of mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS) is considered to be a supportive evidence of the mitochondrial angiopathy theory. Our objectives were to examine whether other neuroimages, especially transcranial color-coded sonography (TCCS), done at the hyperacute stage of stroke-like episode (SLE) is consistent with hypoperfusion of the SLL. We reviewed the magnetic resonance imaging (MRI), SPECT, cerebral angiography, and TCCS of a patient with MELAS ...
Source: Brain and Development - April 20, 2012 Category: Neurology Authors: Hsu-Ling Yeh, Yen-Kung Chen, Wei-Hung Chen, Han-Cheng Wang, Hou-Chang Chiu, Li-Ming Lien, Yau-Huei Wei Tags: Original articles Source Type: research

Pediatric epilepsy following neonatal seizures symptomatic of stroke
Neonatal seizures are a risk factor for later epilepsy and their etiology is known to be implicated in the outcome but, little is known about this issue in the subgroup of seizures symptomatic of perinatal arterial ischemic stroke. The aim of this study was to describe the long term risk of epilepsy after electroencephalographic confirmed neonatal seizures symptomatic of perinatal arterial ischemic stroke.
Source: Brain and Development - June 6, 2015 Category: Neurology Authors: Agnese Suppiej, Massimo Mastrangelo, Laura Mastella, Patrizia Accorsi, Luisa Grazian, Gianluca Casara, Cinzia Peruzzi, Maria Luisa Carpanelli, Augusta Janes, Annalisa Traverso, Bernardo Dalla Bernardina Tags: Original article Source Type: research

A rare infective cause of stroke in an immunocompetent child
Infections are a common cause of childhood stroke with variable presentation. The current case describes a rare infective cause of venous and arterial stroke in an immunocompetent girl with management implications.
Source: Brain and Development - August 23, 2020 Category: Neurology Authors: Juhi Gupta, Biswaroop Chakrabarty, Gagandeep Singh, Sonali Singh, Atin Kumar, Immaculata Xess, Prashant Jauhari, Sheffali Gulati Tags: Case Report Source Type: research

Fetal hydrocephalus and neonatal stroke as the first presentation of protein C deficiency
Severe protein C-deficiency is a rare heritable thrombophilia of the newborn. Infants with biallelic PROC mutations present purpura fulminans and intracranial thromboembolism, while the prenatal onset of mutated heterozygotes remains unclear. We herewith present the first case of fetal ventriculomegaly and neonatal stroke associated with heterozygous PROC mutation. The infant was born to a healthy mother at 38 gestational weeks. The fetal growth had been normal, but the routine ultrasound screening had indicated mild hydrocephalus at 28weeks of gestation.
Source: Brain and Development - August 3, 2015 Category: Neurology Authors: Masako Ichiyama, Shouichi Ohga, Masayuki Ochiai, Kotaro Fukushima, Masataka Ishimura, Michiko Torio, Michiyo Urata, Taeko Hotta, Dongchon Kang, Toshiro Hara Tags: Case Report Source Type: research

Clinical presentation, etiology, and outcome of stroke in children: A hospital-based study
To describe clinical presentations, etiologies, and outcomes of stroke in Jordanian children.
Source: Brain and Development - September 1, 2015 Category: Neurology Authors: Amira Masri, Iyad Al-Ammouri Tags: Original article Source Type: research

Mechanical thrombectomy for pediatric acute stroke and ventricular assist device
Certain pediatric populations have increased risk of ischemic strokes, including those with cardiac disease and those dependent on mechanical circulatory devices such as ventricular assist devices. Due to their need for chronic anticoagulation, patients with mechanical circulatory devices are not candidates for systemic thrombolysis and thus treatment of acute ischemic stroke is limited.
Source: Brain and Development - August 24, 2017 Category: Neurology Authors: Robert Clinton Stowe, Peter Kan, Day Burruss Breen, Sonika Agarwal Tags: Case Report Source Type: research

Challenges and research progress of the use of mesenchymal stem cells in the treatment of ischemic stroke
Cerebral Ischemic Stroke (CIS) has become a hot issue in medical research because of the diversity of risk factors and the uncertainty of prognosis. In the field of regenerative medicine, mesenchymal stem cells (MSCs) have an increasingly prominent position due to their advantages of multiple differentiation, low immunogenicity and wide application. In the basic and clinical research of CIS, there are still some problems to be solved in the treatment of CIS. This paper will discuss the progresses and some obstacles of current MSCs for the treatment of CIS.
Source: Brain and Development - April 13, 2018 Category: Neurology Authors: Jipeng Jiang, Yuting Wang, Baohu Liu, Xuyi Chen, Sai Zhang Tags: Review article Source Type: research

Risk factors and motor outcome of paediatric stroke patients
In this study, we aimed to define the presenting findings, causes, risk factors and motor outcomes of our patients.
Source: Brain and Development - July 20, 2018 Category: Neurology Authors: Zeynep Selen Karalok, Hulya Maras Genc, Birce Dilge Taskin, Nesrin Ceylan, Alev Guven, Nese Yarali Tags: Original article Source Type: research

Epileptic spasm and other forms of epilepsy in presumed perinatal arterial ischemic stroke in Turkey after more than 10  years follow-up: A single centre study
To identify the frequency of epilepsy and whether the association of epilepsy with clinical and neuroimaging findings in children with presumed perinatal arterial ischemic stroke (PPAIS).
Source: Brain and Development - April 15, 2019 Category: Neurology Authors: Gonca Bekta ş, Osman Kipoğlu, Edibe Pembegül Yıldız, Nur Aydınlı, Mine Çalışkan, Meral Özmen, Serra Sencer Tags: Original article Source Type: research

Thalamic aphasia associated with mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes: A case report
Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) with aphasia is a rare disorder, with the associated aphasia reported as either Wernicke ’s or Broca’s. Herein, we report a patient with MELAS complicated by thalamic aphasia.
Source: Brain and Development - May 10, 2022 Category: Neurology Authors: Yurie Sakata, Takuji Nakamura, Fumio Ichinose, Muneaki Matsuo Tags: Case Report Source Type: research

An exploratory study to identify neonatal arterial ischemic stroke: A single-center study
Neonatal arterial ischemic stroke (NAIS) presents as seizures, including convulsions, subtle seizures, and apnea, and most patients experience neurological sequelae. Diagnosis is often delayed owing to low test sensitivity. The present study aimed to identify the early clinical diagnostic factors for NAIS in neonates with seizures.
Source: Brain and Development - September 2, 2022 Category: Neurology Authors: Takashi Setoue, Shuichi Yatsuga, Kazutoshi Ito, Tatsuro Kodera, Yasuhiro Onda, Hiroyasu Kawano, Toshikazu Niimi, Tatsuki Miyamoto, Eiji Ohta, Shinichiro Nagamitsu Tags: Original article Source Type: research

MELAS phenotype associated with m.3302A>G mutation in mitochondrial tRNALeu(UUR) gene
Abstract: The m.3302A>G mutation in the mitochondrial tRNALeu(UUR) gene has been identified in only 12 patients from 6 families, all manifesting adult-onset slowly progressive myopathy with minor central nervous system involvement. An 11-year-old boy presented with progressive proximal-dominant muscle weakness from age 7years. At age 10, he developed recurrent stroke-like episodes. Mitochondrial myopathy, encephalopathy, lactic acidosis, plus stroke-like episodes (MELAS) was diagnosed by clinical symptoms and muscle biopsy findings. Mitochondrial gene analysis revealed a heteroplasmic m.3302A>G mutation. Histological exami...
Source: Brain and Development - April 12, 2013 Category: Neurology Authors: Masahide Goto, Hirofumi Komaki, Takashi Saito, Yoshiaki Saito, Eiji Nakagawa, Kenji Sugai, Masayuki Sasaki, Ichizo Nishino, Yu-ichi Goto Tags: Case reports Source Type: research