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Specialty: Epidemiology
Source: Epidemiologic Perspectives and Innovations

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Total 60 results found since Jan 2013.

Functional performance, nutritional status, and body composition in ambulant community-dwelling individuals 1–3 years after suffering from a cerebral infarction or intracerebral bleeding
Conclusions: Nutritional disorders, i.e., obesity, sarcopenia, or risk for malnutrition, were observed in about one-third of individuals 1 year after stroke. Risk for malnutrition, self-reported physical activity, and age were related to mobility (SPPB), whereas fat-free mass (FFM) and fat mass (FM) were not. Nutrition and exercise treatment could be further evaluated as rehabilitation opportunities after stroke.
Source: Epidemiologic Perspectives and Innovations - February 19, 2016 Category: Epidemiology Authors: Birgit VahlbergLena ZetterbergBirgitta LindmarkKarin HellströmTommy Cederholm Source Type: research

Evaluation of the effects of the Arm Light Exoskeleton on movement execution and muscle activities: a pilot study on healthy subjects
Conclusions: The preliminary analysis on healthy subjects supported the use of ALEx for post-stroke upper limb robotic assisted rehabilitation, and it provided clues on the effects of different rehabilitative strategies on movement and muscle coordination.
Source: Epidemiologic Perspectives and Innovations - January 23, 2016 Category: Epidemiology Authors: Elvira PirondiniMartina CosciaSimone MarcheschiGianluca RoasFabio SalsedoAntonio FrisoliMassimo BergamascoSilvestro Micera Source Type: research

An open source software for analysis of dynamic contrast enhanced magnetic resonance images: UMMPerfusion revisited
Conclusion: We developed open source software to analyse DCE-MRI perfusion data. The software is designed as plugin for the DICOM Workstation OsiriX. It features a clean GUI and provides a simple workflow for data analysis while it could also be seen as a toolbox providing an implementation of several recent compartment models to be applied in research tasks. Integration into the infrastructure of a radiology department is given via OsiriX. Results can be saved automatically and reports generated automatically during data analysis ensure certain quality control.
Source: Epidemiologic Perspectives and Innovations - January 14, 2016 Category: Epidemiology Authors: Frank ZöllnerMarkus DaabSteven SourbronLothar SchadStefan SchoenbergGerald Weisser Source Type: research

Knowledge, attitudes and perceptions of stroke: a cross-sectional survey in rural and urban Uganda
Conclusion: Stroke knowledge is poor in both rural and urban Uganda. Tailored public health approaches that improve stroke awareness, knowledge and self management approaches are urgently needed to develop effective preventive measures and community response to stroke.
Source: Epidemiologic Perspectives and Innovations - December 26, 2015 Category: Epidemiology Authors: Mark KaddumukasaJames KayimaMartin KaddumukasaEdward DdumbaLevi MugenyiSvetlana PundikAnthony FurlanMartha SajatovicElly Katabira Source Type: research

Shift work and the risk of cardiovascular disease among workers in cocoa processing company, Tema
ObjectiveShift work has been implicated in cardiovascular disease (CVD), a major cause of death globally. The aim of this study was to evaluate the risk of developing CVD in shift work.DesignA cross-sectional study involving secondary analysis of shift and non-shift work from an industry in Ghana.ParticipantsTwo hundred (113 shift and 87 non-shift) consecutive workers who consented were recruited into the study. A structured questionnaire was administered to deduce information on participant’s age, alcohol consumption pattern, smoking habits, history of diabetes, stroke and hypertension. Results: Shift workers were found...
Source: Epidemiologic Perspectives and Innovations - December 18, 2015 Category: Epidemiology Authors: Henry Asare-AnaneAdams Abdul-LatifEmmanuel OforiMubarak Abdul-RahmanSeth Amanquah Source Type: research

Synthesis of clinical prediction models under different sets of covariates with one individual patient data
Conclusions: Our proposed methods adequately correct the biases due to different sets of covariates between studies, and would provide precise estimates compared with the conventional approach. If the assumption of homogeneity within studies is plausible, this methodology would be useful for incorporating prior published information into the construction of new prediction models.
Source: Epidemiologic Perspectives and Innovations - November 19, 2015 Category: Epidemiology Authors: Daisuke YoneokaMasayuki HenmiNorie SawadaManami Inoue Source Type: research

Automatic extraction of forward stroke volume using dynamic PET/CT: a dual-tracer and dual-scanner validation in patients with heart valve disease
Background: The aim of this study was to develop and validate an automated method for extracting forward stroke volume (FSV) using indicator dilution theory directly from dynamic positron emission tomography (PET) studies for two different tracers and scanners. Methods: 35 subjects underwent a dynamic 11 C-acetate PET scan on a Siemens Biograph TruePoint-64 PET/CT (scanner I). In addition, 10 subjects underwent both dynamic 15 O-water PET and 11 C-acetate PET scans on a GE Discovery-ST PET/CT (scanner II). The left ventricular (LV)-aortic time-activity curve...
Source: Epidemiologic Perspectives and Innovations - October 26, 2015 Category: Epidemiology Authors: Hendrik HarmsLars TolbodNils HanssonTanja KeroLovisa OrndahlWon KimTomas BjernerKirsten BoucheloucheHenrik WiggersJørgen FrøkiærJens Sörensen Source Type: research

Impaired deformability of circulating erythrocytes obtained from nondiabetic hypertensive patients: investigation by a nickel mesh filtration technique
DiscussionThese findings indicate that erythrocyte deformability is impaired in the hypertensive patients, which depends on the current BP control rather than target organ damage.
Source: Epidemiologic Perspectives and Innovations - October 7, 2015 Category: Epidemiology Authors: Keita OdashiroKazuyuki SaitoTakeshi AritaToru MaruyamaTakehiko FujinoKoichi Akashi Source Type: research

Interference of blood pressure control within 24 hours in acute ischemic stroke: systematic review protocol
No description available
Source: Epidemiologic Perspectives and Innovations - August 15, 2015 Category: Epidemiology Authors: Arnaldo A da SilvaAlvaro N AtallahGisele S SilvaGustavo M Porfírio Source Type: research

The impact of social deprivation on mortality following acute myocardial infarction, stroke or subarachnoid haemorrhage: A record linkage study
Conclusions: We have demonstrated a positive association between social deprivation and higher mortality following emergency admissions for both AMI and stroke. The study findings also suggest that the influence of patient demographics, timing of admission and hospital size on social inequalities in mortality are quite similar for AMI and stroke.
Source: Epidemiologic Perspectives and Innovations - July 17, 2015 Category: Epidemiology Authors: Kymberley ThorneJohn WilliamsAshley AkbariStephen Roberts Source Type: research

Does pragmatically structured outpatient dietary counselling reduce sodium intake in hypertensive patients? Study protocol for a randomized controlled trial
DiscussionThough decreasing sodium intake has been reported to be efficacious in lowering blood pressure, there exists a gap in the evidence for an effective intervention that could be easily translated into clinical practice. If successful, our intervention would be suitable for outpatient programs such as hypertension clinics or interprofessional family practices (family health teams). A negative, or partially negative (positive effect at four weeks with attrition by 12 months) trial outcome also has significant implications for healthcare delivery and use of resources.Trial registrationThe trial was registered with Cli...
Source: Epidemiologic Perspectives and Innovations - June 16, 2015 Category: Epidemiology Authors: Marcel RuzickaTim RamsayAnn BugejaCedric EdwardsGeorge FodorAnne KirbyPeter MagnerBrendan McCormickGigi van der HoefJessica WagnerSwapnil Hiremath Source Type: research

Study protocol of “Worth the Walk”: a randomized controlled trial of a stroke risk reduction walking intervention among racial/ethnic minority older adults with hypertension in community senior centers
DiscussionIf this RCT demonstrates superior improvements in physical activity and stroke knowledge in the intervention group compared to the control group and is found to be sustainable and scalable, Worth the Walk could serve as a primary stroke prevention model for racial/ethnic communities across the nation.Trial registrationClinicalTrials.gov NCT02181062; registered on June 30, 2014.
Source: Epidemiologic Perspectives and Innovations - June 14, 2015 Category: Epidemiology Authors: Ivy KwonSarah ChoiBrian MittmanNazleen BharmalHonghu LiuBarbara VickreySarah SongDaniel AraizaHeather McCreathTeresa SeemanSang-Mi OhLaura TrejoCatherine Sarkisian Source Type: research

Diet patterns and risk of sepsis in community-dwelling adults: a cohort study
Conclusion: A Southern pattern of eating was associated with higher risk of sepsis, particularly among black participants. Determining reasons for these findings may help to devise strategies to reduce sepsis risk.
Source: Epidemiologic Perspectives and Innovations - June 13, 2015 Category: Epidemiology Authors: Orlando GutiérrezSuzanne JuddJenifer VoeksApril CarsonMonika SaffordJames ShikanyHenry Wang Source Type: research

Osteopontin mediates survival, proliferation and migration of neural stem cells through the chemokine receptor CXCR4
Conclusion: Data show positive effects of OPN on survival, proliferation, migration, and neuronal differentiation of NSC. At least in part these effects were mediated via CXCR4. Results suggest that OPN is a promising substance for the targeted activation of NSC in future experimental therapies for neurological disorders such as stroke.
Source: Epidemiologic Perspectives and Innovations - May 21, 2015 Category: Epidemiology Authors: Monika RabensteinJoerg HucklenbroichAntje WilluweitAnne LadwigGereon FinkMichael SchroeterKarl-Josef LangenMaria Rueger Source Type: research

The role of PPAR activation during the systemic response to brain injury
Conclusions: The data highlight a novel mechanism of action for fenofibrate and lend further evidence towards the promotion of its use as a prophylactic therapy in patients at risk of cerebral ischaemia. Further research is required to elucidate the mechanistic explanation underlying its actions.
Source: Epidemiologic Perspectives and Innovations - May 21, 2015 Category: Epidemiology Authors: Patrick LoseyEmma LaddsMaud LapraisBorna GeuvelLaura BurnsRegis BordetDaniel C Anthony Source Type: research