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MR CLEAN, a multicenter randomized clinical trial of endovascular treatment for acute ischemic stroke in the Netherlands: study protocol for a randomized controlled trial
DiscussionIf IAT leads to a 10% absolute reduction in poor outcome after stroke, careful implementation of the intervention could save approximately 1% of all new stroke cases from death or disability annually.Trial registration: NTR1804 (7 May 2009)/ISRCTN10888758 (24 July 2012).
Source: Epidemiologic Perspectives and Innovations - September 1, 2014 Category: Epidemiology Authors: Puck SS FransenDebbie BeumerOlvert A BerkhemerLucie A van den BergHester LingsmaAad van der LugtWim H van ZwamRobert J van OostenbruggeYvo BWEM RoosCharles B MajoieDiederik WJ Dippel Source Type: research

Can minimally invasive puncture and drainage for hypertensive spontaneous Basal Ganglia intracerebral hemorrhage improve patient outcome: a prospective non-randomized comparative study
Background: The treatment of hypertensive spontaneous intracranial hemorrhage (ICH) is still controversial. The purpose of the present study was to investigate whether minimally invasive puncture and drainage (MIPD) could improve patient outcome compared with decompressive craniectomy (DC). Methods: Consecutive patients with ICH (>=30 mL in basal ganglia within 24 hours of ictus) were non-randomly assigned to receive MIPD (group A) or DC (group B) hematoma evacuation. The primary outcome was death at 30 days after onset. Functional independence was assessed at 1 year using the Glasgow Outcome Scale. Results: A total of 198...
Source: Epidemiologic Perspectives and Innovations - June 1, 2014 Category: Epidemiology Authors: Guo-Qiang WangShi-Qiang LiYong-Hua HuangWei-Wei ZhangWen-Wei RuanJia-Zhen QinYing LiWei-Min YinYun-Jun LiZheng-Jun RenJi-Qiang ZhuYun-Yan DingJun-Qi PengPei-Jian Li Source Type: research