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Nonstenotic carotid plaque on CT angiography in patients with cryptogenic stroke
Conclusions: Large but nonstenotic carotid artery plaque is considerably more common ipsilateral than contralateral to cryptogenic stroke, suggesting that nonstenotic plaque is an underrecognized cause of stroke. We measured plaque size using CT angiography, a method that could be easily implemented in clinical practice.
Source: Neurology - August 14, 2016 Category: Neurology Authors: Coutinho, J. M., Derkatch, S., Potvin, A. R. J., Tomlinson, G., Kiehl, T.-R., Silver, F. L., Mandell, D. M. Tags: CT, Stroke prevention, All Cerebrovascular disease/Stroke, Embolism ARTICLE Source Type: research

Early Carotid Revascularization Reduces Readmission for Recurrent Ischemic Stroke in Acute Ischemic Stroke Patients: Analysis of United States Nationwide Readmissions Database (P4.294)
Conclusions:Patients with ischemic stroke undergoing carotid revascularization during the initial hospitalization have significantly lower risk of readmission related to another ischemic strokeDisclosure: Dr. Chaudhry has nothing to disclose. Dr. Gheith has nothing to disclose. Dr. Gu has nothing to disclose. Dr. Afzal has nothing to disclose. Dr. Rahman has nothing to disclose. Dr. Riaz has nothing to disclose. Dr. Sachdeva has nothing to disclose. Dr. Sattar has nothing to disclose. Dr. Razak has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Chaudhry, S., Gheith, T., Gu, S., Afzal, M.-R., Rahman, H., Riaz, A., Sachdeva, G., Sattar, A., Razak, A., Qureshi, A. Tags: In-Hospital Stroke Care Source Type: research

Age and the fuzzy edges of embolic stroke of undetermined source: Implications for trials
After an acute ischemic stroke, clinicians pursue further diagnostic assessment to identify the most plausible causes and tailor secondary prevention strategies. Available treatments with a high level of evidence for reducing recurrence stroke risk might include long-term oral anticoagulation in patients with a major-risk cardioembolic source (atrial fibrillation, prosthetic valves, etc), carotid endarterectomy in minor ischemic stroke related to moderate to severe internal carotid artery atherosclerotic stenosis, and best-practice medical management in those with lacunar stroke due to cerebral small vessel disease.1 Howev...
Source: Neurology - August 7, 2017 Category: Neurology Authors: Charidimou, A. Tags: Stroke in young adults, All Clinical trials, All Cerebrovascular disease/Stroke, Embolism, Infarction EDITORIALS Source Type: research

Recurrent stroke in symptomatic carotid stenosis awaiting revascularization: A pooled analysis
Conclusions: We found high risk of recurrent ipsilateral ischemic events within the 14-day time period currently recommended for CEA. Randomized trials are needed to determine the benefits and safety of urgent vs subacute carotid revascularization within 14 days after symptom onset.
Source: Neurology - February 8, 2016 Category: Neurology Authors: Johansson, E., Cuadrado-Godia, E., Hayden, D., Bjellerup, J., Ois, A., Roquer, J., Wester, P., Kelly, P. J. Tags: All Cerebrovascular disease/Stroke ARTICLE Source Type: research

Hospital costs of ischemic stroke and TIA in the Netherlands
Conclusions: Hospital costs are higher for inpatients and ischemic strokes compared with outpatients and TIAs, with length of stay (LOS) the most important contributor. LOS and hospital costs have substantially declined over the last 10 years, possibly due to improved hospital stroke care and efficient integrated stroke services.
Source: Neurology - June 1, 2015 Category: Neurology Authors: Buisman, L. R., Tan, S. S., Nederkoorn, P. J., Koudstaal, P. J., Redekop, W. K. Tags: Cost effectiveness/economic, Medical care, Infarction ARTICLE Source Type: research

A Systematic Literature Review of Patients with Carotid Web and Acute Ischemic Stroke. (P5.286)
Conclusions:CW is a rare disease leading to ischemic stroke in younger patients without typical CV risk factors. CW patients in our SLR were at extremely high risk for recurrent stroke (47.8%). Aggressive secondary stroke prevention measures are indicated in this patient population, however, the optimal treatment strategies remain unclear. Carotid revascularization may be the definitive treatment for certain patients with CW, but further studies are needed as incomplete reporting and potential publication bias limit our findings.Disclosure: Dr. Dhruv has nothing to disclose. Dr. Kim has nothing to disclose. Dr. Koffel has ...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Dhruv, P., Kim, J., Koffel, J., Anderson, D., Streib, C. Tags: SubAcute Interventional Therapies in Cerebrovascular Disease Source Type: research

Prevalence, Risk Factors, and Clinical Significance of Asymptomatic Extracranial Vertebral Artery Disease in Patients with Symptomatic Internal Carotid Artery Stenosis: Analysis of Stent-Protected Angioplasty versus Carotid Endarterectomy (SPACE) Trial (S42.002)
Conclusions: There appears to be an increased risk of stroke and death in patients with symptomatic internal carotid artery stenosis with concurrent asymptomatic extracranial vertebral artery stenosis. Key words: Extracranial vertebral artery; carotid stenosis; vertebral artery stenosis; vertebral artery occlusion; stroke; death.Disclosure: Dr. Qureshi has nothing to disclose. Dr. Chaudhry has nothing to disclose. Dr. Jansen has nothing to disclose. Dr. Eckstein has nothing to disclose. Dr. Ringleb has nothing to disclose.
Source: Neurology - February 7, 2016 Category: Neurology Authors: Qureshi, A., Chaudhry, S., Jansen, O., Eckstein, H.-H., Ringleb, P. Tags: Stroke Mechanism and Modifiers Source Type: research

Pattern of Utilization of Carotid Endarterectomy in Acute Ischemic Stroke Patients Undergoing Early Carotid Endarterectomy According to Severity of Neurological Deficits and Infarct Size (P5.277)
Conclusions:CEA was performed in ischemic stroke patients with minor or moderate infarction on CT scan with an acceptable rate of recurrent stroke and death and without any adverse functional outcome.Disclosure: Dr. Ahrar has nothing to disclose. Dr. Qureshi has nothing to disclose. Dr. Saleem has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ahrar, A., Qureshi, A., Saleem, M. Tags: SubAcute Interventional Therapies in Cerebrovascular Disease Source Type: research

Symptomatic Carotid Near-Occlusion With String Sign Incurs A Very High Risk Of Stroke (P7.169)
CONCLUSIONS: Patients with symptomatic carotid near-occlusions with string sign have a very high risk of stroke recurrence. Urgent carotid endarterectomy should be considered for these patients.Study Supported by:Disclosure: Dr. Johansson has nothing to disclose. Dr. Wester has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Johansson, E., Wester, P. Tags: Cerebrovascular Disease and Interventional Neurology: Carotid Disease Source Type: research

Utilization of Carotid Revascularization for Ischemic Stroke/TIA: A Canadian Perspective (P5.276)
Conclusions:Use of CEA/CAS in patients with acute ischemic stroke/TIA admitted to hospitals in Canada has doubled over the last decade. Differences in utilization by age, sex and across provinces are seen.Disclosure: Dr. Najm has nothing to disclose. Dr. Lindsay has nothing to disclose. Dr. Hill has nothing to disclose. Dr. Demchuk has nothing to disclose. Dr. Menon has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Najm, M., Lindsay, P., Hill, M. D., Demchuk, A., Menon, B. Tags: SubAcute Interventional Therapies in Cerebrovascular Disease Source Type: research

Stroke in a Young Woman Caused by Carotid Web (P1.024)
CONCLUSIONS: A carotid web increases stroke risk through thromboembolism. Unlike in other forms of carotid FMD, endarterectomy removes the focus of thrombosis without need for anticoagulation. Alternatively, anticoagulation or antiplatelet therapy might decrease stroke risk but would burden a young patient with increased lifetime risk of bleeding. Study Supported by: N/ADisclosure: Dr. Petrsoric has nothing to disclose. Dr. DeNiro has nothing to disclose. Dr. Labovitz has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Petrsoric, J., DeNiro, L., Labovitz, D. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Unusual Intersection: Elucidating the Role of Erdheim Chester Disease in Stroke (P4.366)
Conclusion:A unifying diagnosis of ECD was identified for this gentleman presenting with a stroke in the setting of critical ICA stenosis. Pathology from his CEA suggests that while ECD involves multisystem inflammation, it did not appear to play a direct role in his stroke.Disclosure: Dr. Sheikhi has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Sheikhi, L. Tags: Cerebrovascular Case Reports Source Type: research

Body mass index and outcome after revascularization for symptomatic carotid artery stenosis
Conclusions: BMI is not associated with periprocedural risk of stroke or death; however, BMI 25–<30 is associated with lower postprocedural risk than BMI 20–<25. These observations were similar for CAS and CEA.
Source: Neurology - May 22, 2017 Category: Neurology Authors: Volkers, E. J., Greving, J. P., Hendrikse, J., Algra, A., Kappelle, L. J., Becquemin, J.-P., Bonati, L. H., Brott, T. G., Bulbulia, R., Calvet, D., Eckstein, H.-H., Fraedrich, G., Gregson, J., Halliday, A., Howard, G., Jansen, O., Roubin, G. S., Brown, M. Tags: Stroke prevention, Clinical trials Systematic review/meta analysis, Risk factors in epidemiology, Infarction ARTICLE Source Type: research

Temporal trends in safety of carotid endarterectomy in asymptomatic patients: Systematic review
Conclusions: CEA is safer than ever before and high-volume registry results closely mirror the results of trials. New benchmarks for CEA are a stroke or death risk of 1.2% and a mortality risk of 0.4%. This information will prove useful for quality improvement programs, for health care funders, and for those re-examining the long-term benefits of asymptomatic revascularization in future trials.
Source: Neurology - July 27, 2015 Category: Neurology Authors: Munster, A. B., Franchini, A. J., Qureshi, M. I., Thapar, A., Davies, A. H. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Patient safety, All epidemiology VIEWS & amp;amp; REVIEWS Source Type: research

Natural History of Extracranial Carotid Stenosis in Asian Stroke Patients- A Retrospective Study (P1.182)
Conclusions- Symptomatic steno-occlusive disease of cervical carotid artery carries a high risk of subsequent vascular events and mortality despite best medical therapy. Perhaps, better methods of risk stratification and an aggressive approach towards revascularisation in eligible cases are warranted.Disclosure: Dr. Chandra has nothing to disclose. Dr. Woo has nothing to disclose. Dr. Woo has nothing to disclose. Dr. Liu has nothing to disclose. Dr. Kulkarni has nothing to disclose. Dr. Sharma has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Chandra, B., Woo, J. W., Woo, R. W., Liu, R. J., Kulkarni, A., Sharma, V. Tags: Cerebrovascular Disease: Risk Factors and Prevention Source Type: research

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