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Total 234 results found since Jan 2013.

Stroke Risk Factors, Subtypes, and 30-Day Case Fatality in Abuja, Nigeria (P1.121)
CONCLUSIONS: Although hypertension, obesity, diabetes mellitus, and atrial fibrillation were important stroke risk factors, in many patients, these were detected only after a stroke. While the commonest stroke subtype was cerebral infarction, observed in almost two-third of patients, SAH was associated with the highest case-fatality rate at 30 days of 44.4%. Larger population-based studies are planned.Study Supported by: nilDisclosure: Dr. Bwala has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Bwala, S. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Subtype Source Type: research

An Initiative To Improve Door To Needle Time For Stroke Thrombolysis In Chicago (P7.129)
CONCLUSIONS:We identified several opportunities for improvement in DTN times at Chicago’s PSCs. Using a regional face-to-face educational program, we have initiated a plan to decrease DTN time in Chicago. Preliminary results suggest major improvements in short period of time.Study Supported by: GenentechDisclosure: Dr. Prabhakaran has received personal compensation for activities with American Heart Association. Dr. O'Neill has received research support from Genentech, Inc.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Prabhakaran, S., O'Neill, K. Tags: Cerebrovascular Disease and Interventional Neurology: Barriers and Opportunities in Acute Stroke Treatment Source Type: research

Shared genetic susceptibility of vascular-related biomarkers with ischemic and recurrent stroke
Conclusions: Our data identify a genetic contribution to inflammatory and hemostatic biomarkers in a stroke population. Additionally, our results suggest shared genetic contributions to circulating CRP levels measured poststroke and risk for incident and recurrent ischemic stroke. These data broaden our understanding of genetic contributors to biomarker variation and ischemic stroke risk, which should be useful in clinical risk evaluation.
Source: Neurology - January 25, 2016 Category: Neurology Authors: Williams, S. R., Hsu, F.-C., Keene, K. L., Chen, W.-M., Nelson, S., Southerland, A. M., Madden, E. B., Coull, B., Gogarten, S. M., Furie, K. L., Dzhivhuho, G., Rowles, J. L., Mehndiratta, P., Malik, R., Dupuis, J., Lin, H., Seshadri, S., Rich, S. S., Sale Tags: All Cerebrovascular disease/Stroke, Case control studies, Risk factors in epidemiology, All Genetics, Association studies in genetics ARTICLE Source Type: research

Reliability of brain CT evaluation by stroke neurologists in telemedicine
Conclusions: Clinically relevant misinterpretation of the CT scans was rare in our acute telestroke service. ASPECTS is a reliable tool to assess the extent of EIC by stroke neurologists in telemedicine in real time.
Source: Neurology - January 21, 2013 Category: Neurology Authors: Puetz, V., Bodechtel, U., Gerber, J. C., Dzialowski, I., Kunz, A., Wolz, M., Hentschel, H., Schultheiss, T., Kepplinger, J., Schneider, H., Wiedemann, B., Wojciechowski, C., Reichmann, H., Gahn, G., von Kummer, R. Tags: Diagnostic test assessment, CT, All Cerebrovascular disease/Stroke ARTICLE Source Type: research

Pre-hospital imaging and thrombolysis in acute stroke in an urban US setting: results of the Cleveland Pre-Hospital Acute Stroke Treatment (PHAST) study group. (S21.002)
CONCLUSIONS: Close to a fifth of patients received acute stroke treatment on MSTU. These findings demonstrate the successful reduction in time to diagnosis and treatment of acute stroke patients using a MSTU. Study Supported by:Disclosure: Dr. Briggs has nothing to disclose. Dr. Taqui has nothing to disclose. Dr. Cerejo has nothing to disclose. Dr. Itrat has nothing to disclose. Dr. Donohue has nothing to disclose. Dr. Organek has nothing to disclose. Dr. Buletko has nothing to disclose. Dr. Sheikhi has nothing to disclose. Dr. Buttrick has nothing to disclose. Dr. Khawaja has nothing to disclose. Dr. Wisco has nothing to ...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Briggs, F., Taqui, A., Cerejo, R., Itrat, A., Donohue, M., Organek, N., Buletko, A., Sheikhi, L., Buttrick, M., Khawaja, Z., Wisco, D., Winners, S., Reimer, A., Frontera, J., Manno, E., Hustey, F., Kralovic, D., Peter, R., Hussain, M., Uchino, K. Tags: Cerebrovascular Disease and Interventional Neurology: Prehospital and Acute Ischemic Stroke Treatment Source Type: research

Structural MRI markers of brain aging early after ischemic stroke
Conclusions: Brain structure is likely to be compromised before ischemic stroke by vascular risk factors. Smaller hippocampal and total brain volumes and increased WMH load represent proxies for underlying vascular brain injury.
Source: Neurology - July 10, 2017 Category: Neurology Authors: Werden, E., Cumming, T., Li, Q., Bird, L., Veldsman, M., Pardoe, H. R., Jackson, G., Donnan, G. A., Brodtmann, A. Tags: MRI, All Cerebrovascular disease/Stroke, Clinical trials Observational study (Cohort, Case control), Alzheimer's disease, Vascular dementia ARTICLE Source Type: research

Incidence, short-term outcome, and spatial distribution of stroke patients in Ludhiana, India
Conclusions: The incidence rates are similar to other studies from India. Stroke patient survival is poor in public hospitals. The finding of spatial analysis is of public health significance for stroke prevention and strengthening of stroke services.
Source: Neurology - February 1, 2016 Category: Neurology Authors: Pandian, J. D., Singh, G., Kaur, P., Bansal, R., Paul, B. S., Singla, M., Singh, S., Samuel, C. J., Verma, S. J., Moodbidri, P., Mehmi, G., Sharma, A., Arora, O. P., Dhanuka, A. K., Sobti, M. K., Sehgal, H., Kaur, M., Grewal, S. S., Jhawar, S. S., Shadang Tags: All Cerebrovascular disease/Stroke, Incidence studies ARTICLE Source Type: research

Stroke Code to CT - Does Stroke Severity Affect Timing? (P2.311)
CONCLUSIONS: It is imperative that we act upon patients with less severe appearing strokes with as much rapidity as we do for those with severe strokes in order to ensure that all stroke patients have the best chance for long-term recovery.Disclosure: Dr. Kwei has nothing to disclose. Dr. Wilson has nothing to disclose. Dr. Liang has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Kwei, K., Wilson, N., Liang, J. Tags: Stroke Systems of Care Source Type: research

Clinical and imaging characteristics of silent brain infarction and symptomatic stroke (P4.257)
Conclusions:In an imaging-defined brain infarct cohort, SBI is highly prevalent and encompasses a spectrum of clinical presentations. The majority of individuals with SBI have no documented symptoms or deficits.Disclosure: Dr. Albazli has nothing to disclose. Dr. Leung has nothing to disclose. Dr. Huggins has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Albazli, K., Leung, L., Huggins, H. Tags: Acute and Diagnostic Imaging in Ischemic Stroke and TIA Source Type: research

Disruption of the Blood-Ocular Barriers in Stroke Patients (S8.008)
Conclusions:GLOS is common in stroke patients regardless of whether they receive treatment. BBB disruption appears to associate with blood-ocular barrier disruption. Whether these findings are due to the acute stroke, or merely due to a common underlying chronic process, remains to be determined.Disclosure: Dr. Hitomi has nothing to disclose. Dr. Latour has nothing to disclose. Dr. Leigh has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Hitomi, E., Latour, L. L., Leigh, R. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Stroke Treatment Source Type: research

Prehospital thrombolysis in acute stroke: Results of the PHANTOM-S pilot study
Conclusions: The data suggest that prehospital stroke care in STEMO is feasible. No safety concerns have been raised so far. This new approach using prehospital tPA may be effective in reducing call-to-needle times, but this is currently being scrutinized in a prospective controlled study.
Source: Neurology - January 7, 2013 Category: Neurology Authors: Weber, J. E., Ebinger, M., Rozanski, M., Waldschmidt, C., Wendt, M., Winter, B., Kellner, P., Baumann, A., Fiebach, J. B., Villringer, K., Kaczmarek, S., Endres, M., Audebert, H. J., for the STEMO-Consortium Tags: CT, All Cerebrovascular disease/Stroke, Critical care, Patient safety ARTICLE Source Type: research

Prehospital stroke care: New prospects for treatment and clinical research
Brain cells die rapidly after stroke and any effective treatment must start as early as possible. In clinical routine, the tight time–outcome relationship continues to be the major limitation of therapeutic approaches: thrombolysis rates remain low across many countries, with most patients being treated at the late end of the therapeutic window. In addition, there is no neuroprotective therapy available, but some maintain that this concept may be valid if administered very early after stroke. Recent innovations have opened new perspectives for stroke diagnosis and treatment before the patient arrives at the hospital....
Source: Neurology - July 29, 2013 Category: Neurology Authors: Audebert, H. J., Saver, J. L., Starkman, S., Lees, K. R., Endres, M. Tags: All Clinical trials, All Cerebrovascular disease/Stroke VIEWS & amp;amp; REVIEWS Source Type: research

Does Emergency department length of stay affect the 90-day functional outcome after acute ischemic stroke? (P3.073)
Conclusion: In our cohort, there was no association between the ED-LOS and 90-day functional outcome. Further study is ongoing to assess whether ED-LOS adversely affects outcome measures not captured by the mRS.Disclosure: Dr. Patel has nothing to disclose. Dr. Minaeian has nothing to disclose. Dr. Tunguturi has nothing to disclose. Dr. Goddeau has nothing to disclose. Dr. Henninger has received personal compensation in an editorial capacity for Stroke.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Patel, A., Minaeian, A., Tunguturi, A., Goddeau, R., Henninger, N. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Outcome Source Type: research

DCE-MRI blood-brain barrier assessment in acute ischemic stroke
Conclusion: BBB in acute stroke patients can be successfully assessed quantitatively. The decrease of BBB permeability in unaffected regions at follow-up may be an indicator of global BBB leakage even in vessel territories remote from the index infarct.
Source: Neurology - January 29, 2017 Category: Neurology Authors: Villringer, K., Sanz Cuesta, B. E., Ostwaldt, A.-C., Grittner, U., Brunecker, P., Khalil, A. A., Schindler, K., Eisenblätter, O., Audebert, H., Fiebach, J. B. Tags: Diagnostic test assessment, MRI, All Cerebrovascular disease/Stroke ARTICLE Source Type: research

Target Stroke Implementation: Best Practice Strategies Cut Thrombolysis Time to < 30 minutes in a 1,550 Bed Academic Urban County Hospital (P4.280)
Conclusions:Individualized hospital gap analysis identifies targeted interventions to shorten treatment times. DTN and DTG time can be reduced with implementation of simple, low-cost interventions, with persistent effect and no increase in symptomatic intracranial hemorrhage or stroke mimic treatment.Disclosure: Dr. Marulanda-Londoño has nothing to disclose. Dr. Bhatt has nothing to disclose. Dr. Atchaneeyasakul has nothing to disclose. Dr. Asdaghi has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Akram has nothing to disclose. Dr. Zhang has nothing to disclose. Dr. D’Amour has nothing to disclos...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Marulanda-Londono, E., Bhatt, N., Atchaneeyasakul, K., Asdaghi, N., Malik, A., Akram, N., Zhang, T., DAmour, D., Hesse, K., Sacco, R., Romano, J. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research