Filtered By:
Specialty: Research
Source: Nucl Recept Signal
This page shows you your search results in order of date.
Order by Relevance | Date
Total 1562 results found since Jan 2013.
Using Chromatin-Nuclear Receptor Interactions to Quantitate Endocrine, Paracrine, and Autocrine Signaling
Nucl Recept Signal. 2020 Feb 27;17:1550762919899643. doi: 10.1177/1550762919899643. eCollection 2020.ABSTRACTHormone-activated nuclear receptors (NRs) control myriad cellular processes. The classical paradigm for hormone delivery is secretion from endocrine organs and blood-borne distribution to responding cells. However, many hormones can also be synthesized in the same tissues in which responding cells are found (paracrine signaling). In both endocrine and paracrine signaling, numerous factors affect hormone availability to target cell NRs, including hormone access to and sequestration by carrier proteins, transport acro...
Source: Nucl Recept Signal - May 18, 2022 Category: Research Authors: Matthew D Taves Jonathan D Ashwell Source Type: research
PPAR-gamma Fun(gi) With Prostaglandin
Nucl Recept Signal. 2020 Jan 23;17:1550762919899641. doi: 10.1177/1550762919899641. eCollection 2020.ABSTRACTIn our recent publication, we show for the first time that the fungal pathogen Cryptococcus neoformans is able to manipulate host cells by producing eicosanoids that mimic those found in the host. Using complementary in vivo zebrafish and in vitro macrophage cell culture models of Cryptococcus infection, we found that these eicosanoids manipulate host innate immune cells by activating the host receptor PPAR-gamma which is an important regulator of macrophage inflammatory phenotypes. We initially identified PGE2 as t...
Source: Nucl Recept Signal - May 18, 2022 Category: Research Authors: Robert J Evans Simon A Johnston Source Type: research
Using Chromatin-Nuclear Receptor Interactions to Quantitate Endocrine, Paracrine, and Autocrine Signaling
Nucl Recept Signal. 2020 Feb 27;17:1550762919899643. doi: 10.1177/1550762919899643. eCollection 2020.ABSTRACTHormone-activated nuclear receptors (NRs) control myriad cellular processes. The classical paradigm for hormone delivery is secretion from endocrine organs and blood-borne distribution to responding cells. However, many hormones can also be synthesized in the same tissues in which responding cells are found (paracrine signaling). In both endocrine and paracrine signaling, numerous factors affect hormone availability to target cell NRs, including hormone access to and sequestration by carrier proteins, transport acro...
Source: Nucl Recept Signal - May 18, 2022 Category: Research Authors: Matthew D Taves Jonathan D Ashwell Source Type: research
PPAR-gamma Fun(gi) With Prostaglandin
Nucl Recept Signal. 2020 Jan 23;17:1550762919899641. doi: 10.1177/1550762919899641. eCollection 2020.ABSTRACTIn our recent publication, we show for the first time that the fungal pathogen Cryptococcus neoformans is able to manipulate host cells by producing eicosanoids that mimic those found in the host. Using complementary in vivo zebrafish and in vitro macrophage cell culture models of Cryptococcus infection, we found that these eicosanoids manipulate host innate immune cells by activating the host receptor PPAR-gamma which is an important regulator of macrophage inflammatory phenotypes. We initially identified PGE2 as t...
Source: Nucl Recept Signal - May 18, 2022 Category: Research Authors: Robert J Evans Simon A Johnston Source Type: research
Using Chromatin-Nuclear Receptor Interactions to Quantitate Endocrine, Paracrine, and Autocrine Signaling
Nucl Recept Signal. 2020 Feb 27;17:1550762919899643. doi: 10.1177/1550762919899643. eCollection 2020.ABSTRACTHormone-activated nuclear receptors (NRs) control myriad cellular processes. The classical paradigm for hormone delivery is secretion from endocrine organs and blood-borne distribution to responding cells. However, many hormones can also be synthesized in the same tissues in which responding cells are found (paracrine signaling). In both endocrine and paracrine signaling, numerous factors affect hormone availability to target cell NRs, including hormone access to and sequestration by carrier proteins, transport acro...
Source: Nucl Recept Signal - May 18, 2022 Category: Research Authors: Matthew D Taves Jonathan D Ashwell Source Type: research
PPAR-gamma Fun(gi) With Prostaglandin
Nucl Recept Signal. 2020 Jan 23;17:1550762919899641. doi: 10.1177/1550762919899641. eCollection 2020.ABSTRACTIn our recent publication, we show for the first time that the fungal pathogen Cryptococcus neoformans is able to manipulate host cells by producing eicosanoids that mimic those found in the host. Using complementary in vivo zebrafish and in vitro macrophage cell culture models of Cryptococcus infection, we found that these eicosanoids manipulate host innate immune cells by activating the host receptor PPAR-gamma which is an important regulator of macrophage inflammatory phenotypes. We initially identified PGE2 as t...
Source: Nucl Recept Signal - May 18, 2022 Category: Research Authors: Robert J Evans Simon A Johnston Source Type: research
Using Chromatin-Nuclear Receptor Interactions to Quantitate Endocrine, Paracrine, and Autocrine Signaling
Nucl Recept Signal. 2020 Feb 27;17:1550762919899643. doi: 10.1177/1550762919899643. eCollection 2020.ABSTRACTHormone-activated nuclear receptors (NRs) control myriad cellular processes. The classical paradigm for hormone delivery is secretion from endocrine organs and blood-borne distribution to responding cells. However, many hormones can also be synthesized in the same tissues in which responding cells are found (paracrine signaling). In both endocrine and paracrine signaling, numerous factors affect hormone availability to target cell NRs, including hormone access to and sequestration by carrier proteins, transport acro...
Source: Nucl Recept Signal - May 18, 2022 Category: Research Authors: Matthew D Taves Jonathan D Ashwell Source Type: research
PPAR-gamma Fun(gi) With Prostaglandin
Nucl Recept Signal. 2020 Jan 23;17:1550762919899641. doi: 10.1177/1550762919899641. eCollection 2020.ABSTRACTIn our recent publication, we show for the first time that the fungal pathogen Cryptococcus neoformans is able to manipulate host cells by producing eicosanoids that mimic those found in the host. Using complementary in vivo zebrafish and in vitro macrophage cell culture models of Cryptococcus infection, we found that these eicosanoids manipulate host innate immune cells by activating the host receptor PPAR-gamma which is an important regulator of macrophage inflammatory phenotypes. We initially identified PGE2 as t...
Source: Nucl Recept Signal - May 18, 2022 Category: Research Authors: Robert J Evans Simon A Johnston Source Type: research
Using Chromatin-Nuclear Receptor Interactions to Quantitate Endocrine, Paracrine, and Autocrine Signaling
Nucl Recept Signal. 2020 Feb 27;17:1550762919899643. doi: 10.1177/1550762919899643. eCollection 2020.ABSTRACTHormone-activated nuclear receptors (NRs) control myriad cellular processes. The classical paradigm for hormone delivery is secretion from endocrine organs and blood-borne distribution to responding cells. However, many hormones can also be synthesized in the same tissues in which responding cells are found (paracrine signaling). In both endocrine and paracrine signaling, numerous factors affect hormone availability to target cell NRs, including hormone access to and sequestration by carrier proteins, transport acro...
Source: Nucl Recept Signal - May 18, 2022 Category: Research Authors: Matthew D Taves Jonathan D Ashwell Source Type: research
PPAR-gamma Fun(gi) With Prostaglandin
Nucl Recept Signal. 2020 Jan 23;17:1550762919899641. doi: 10.1177/1550762919899641. eCollection 2020.ABSTRACTIn our recent publication, we show for the first time that the fungal pathogen Cryptococcus neoformans is able to manipulate host cells by producing eicosanoids that mimic those found in the host. Using complementary in vivo zebrafish and in vitro macrophage cell culture models of Cryptococcus infection, we found that these eicosanoids manipulate host innate immune cells by activating the host receptor PPAR-gamma which is an important regulator of macrophage inflammatory phenotypes. We initially identified PGE2 as t...
Source: Nucl Recept Signal - May 18, 2022 Category: Research Authors: Robert J Evans Simon A Johnston Source Type: research
Using Chromatin-Nuclear Receptor Interactions to Quantitate Endocrine, Paracrine, and Autocrine Signaling
Nucl Recept Signal. 2020 Feb 27;17:1550762919899643. doi: 10.1177/1550762919899643. eCollection 2020.ABSTRACTHormone-activated nuclear receptors (NRs) control myriad cellular processes. The classical paradigm for hormone delivery is secretion from endocrine organs and blood-borne distribution to responding cells. However, many hormones can also be synthesized in the same tissues in which responding cells are found (paracrine signaling). In both endocrine and paracrine signaling, numerous factors affect hormone availability to target cell NRs, including hormone access to and sequestration by carrier proteins, transport acro...
Source: Nucl Recept Signal - May 18, 2022 Category: Research Authors: Matthew D Taves Jonathan D Ashwell Source Type: research
PPAR-gamma Fun(gi) With Prostaglandin
Nucl Recept Signal. 2020 Jan 23;17:1550762919899641. doi: 10.1177/1550762919899641. eCollection 2020.ABSTRACTIn our recent publication, we show for the first time that the fungal pathogen Cryptococcus neoformans is able to manipulate host cells by producing eicosanoids that mimic those found in the host. Using complementary in vivo zebrafish and in vitro macrophage cell culture models of Cryptococcus infection, we found that these eicosanoids manipulate host innate immune cells by activating the host receptor PPAR-gamma which is an important regulator of macrophage inflammatory phenotypes. We initially identified PGE2 as t...
Source: Nucl Recept Signal - May 18, 2022 Category: Research Authors: Robert J Evans Simon A Johnston Source Type: research
Using Chromatin-Nuclear Receptor Interactions to Quantitate Endocrine, Paracrine, and Autocrine Signaling
Nucl Recept Signal. 2020 Feb 27;17:1550762919899643. doi: 10.1177/1550762919899643. eCollection 2020.ABSTRACTHormone-activated nuclear receptors (NRs) control myriad cellular processes. The classical paradigm for hormone delivery is secretion from endocrine organs and blood-borne distribution to responding cells. However, many hormones can also be synthesized in the same tissues in which responding cells are found (paracrine signaling). In both endocrine and paracrine signaling, numerous factors affect hormone availability to target cell NRs, including hormone access to and sequestration by carrier proteins, transport acro...
Source: Nucl Recept Signal - May 18, 2022 Category: Research Authors: Matthew D Taves Jonathan D Ashwell Source Type: research
PPAR-gamma Fun(gi) With Prostaglandin
Nucl Recept Signal. 2020 Jan 23;17:1550762919899641. doi: 10.1177/1550762919899641. eCollection 2020.ABSTRACTIn our recent publication, we show for the first time that the fungal pathogen Cryptococcus neoformans is able to manipulate host cells by producing eicosanoids that mimic those found in the host. Using complementary in vivo zebrafish and in vitro macrophage cell culture models of Cryptococcus infection, we found that these eicosanoids manipulate host innate immune cells by activating the host receptor PPAR-gamma which is an important regulator of macrophage inflammatory phenotypes. We initially identified PGE2 as t...
Source: Nucl Recept Signal - May 18, 2022 Category: Research Authors: Robert J Evans Simon A Johnston Source Type: research
