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Source: LANCET
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Total 186 results found since Jan 2013.
Department of Error Department of Error
Breitenstein C, Grewe T, Fl öel A, et al. Intensive speech and language therapy in patients with chronic aphasia after stroke: a randomised, open-label, blinded-endpoint, controlled trial in a health-care setting. Lancet 2017; 389: 1528–38—In this Article, S Runge should have been listed as part of the FCET2EC study group as a non-author collaborator. This change has been made to the online version as of April 13, 2017, and the printed Article is correct.
Source: LANCET - April 14, 2017 Category: Journals (General) Tags: Department of Error Source Type: research
Obituary Peter Mansfield
Nobel Prize winning inventor of magnetic resonance imaging. He was born in London, UK, on Oct 9, 1933, and died in Nottingham, UK, after a stroke on Feb 8, 2017, aged 83 years.
Source: LANCET - April 20, 2017 Category: Journals (General) Authors: Geoff Watts Tags: Obituary Source Type: research
Department of Error Department of Error
The AVERT Trial Collaboration group. Efficacy and safety of very early mobilisation within 24 h of stroke onset (AVERT): a randomised controlled trial. Lancet 2015; 386: 46 –55—This Open Access Article should have been distributed under the terms of CC BY. This correction has been made to the online version as of May 11, 2017.
Source: LANCET - May 12, 2017 Category: General Medicine Tags: Department of Error Source Type: research
Articles Achieved blood pressure and cardiovascular outcomes in high-risk patients: results from ONTARGET and TRANSCEND trials
Mean achieved SBP less than 120 mm Hg during treatment was associated with increased risk of cardiovascular outcomes except for myocardial infarction and stroke. Similar patterns were observed for DBP less than 70 mm Hg, plus increased risk for myocardial infarction and hospital admission for heart failure. Very low blood pressure achieved on treatment was associated with increased risks of several cardiovascular disease events. These data suggest that the lowest blood pressure possible is not necessarily the optimal target for high-risk patients, although it is not possible to rule out some effect of reverse causality.
Source: LANCET - April 5, 2017 Category: General Medicine Authors: Michael B öhm, Helmut Schumacher, Koon K Teo, Eva M Lonn, Felix Mahfoud, Johannes F E Mann, Giuseppe Mancia, Josep Redon, Roland E Schmieder, Karen Sliwa, Michael A Weber, Bryan Williams, Salim Yusuf Tags: Articles Source Type: research
Comment Bioprosthetic surgical and transcatheter heart valve thrombosis
Excellent outcomes of transcatheter aortic valve replacement (TAVR) have been experienced by patients with aortic stenosis at high and intermediate risk of surgery.1 Findings from large randomised trials1,2 have shown survival with TAVR that is similar to or improved compared with bioprosthetic surgical aortic valve replacement (SAVR), and very low stroke rates have been observed with new-generation devices. Investigators of echocardiographic follow-up studies3 have consistently reported low transvalvular gradients up to 5 years after TAVR and SAVR, with slightly greater aortic valve areas after TAVR than after SAVR.
Source: LANCET - March 19, 2017 Category: General Medicine Authors: Jeroen J Bax, Gregg W Stone Tags: Comment Source Type: research
Department of Error Department of Error
Cohen AJ, Brauer M, Burnett R, et al. Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015. Lancet 2016; 389: 1907 –18—In this Article, the following changes have been made to the supplementary appendix. In table 1, for the Pinault et al11 study, the country, the CEV (Stroke)-Relative Risk (95% CI), and the IHD-Relative Risk (95% CI) have been corrected (p 11); the second Pinault et al11 reference has been c hanged to Thurston et al (2016; p 11); a footnote has been added stating that the indicated data were...
Source: LANCET - May 23, 2017 Category: General Medicine Tags: Department of Error Source Type: research
Comment Preventing major gastrointestinal bleeding in elderly patients
Antiplatelet therapy is the most frequently recommended treatment to prevent recurrent ischaemic events in patients who have had an ischaemic stroke, an acute coronary syndrome, or symptomatic peripheral arterial disease. The most frequently used drugs are aspirin or clopidogrel. Most guidelines recommend lifelong intake of antiplatelet therapy. However, randomised trials that have investigated the benefit of antiplatelet therapy had an observation period of between 2 years and 4 years.1 Therefore, we lack data on the long-term benefit and risk of antiplatelet therapy across long time periods, particularly in elderly patients.
Source: LANCET - June 13, 2017 Category: General Medicine Authors: Hans-Christoph Diener Tags: Comment Source Type: research
Department of Error Department of Error
ATTEND Collaborative Group. Family-led rehabilitation after stroke in India (ATTEND): a randomised controlled trial. Lancet 2017; 390: 588 –99—In the Summary of this Article, the number of patients lost to follow-up should have been 33. This correction has been made to the online version as of Aug 3, 2017, and the printed Article is correct.
Source: LANCET - August 4, 2017 Category: General Medicine Tags: Department of Error Source Type: research
Comment Building evidence for care beyond the medical centre
Digital health has been defined as the “convergence of the digital and genomic revolutions with health, health care, living, and society”.1 The term is often used interchangeably with mHealth or mobile health because of the central role played by mobile devices. Remote patient monitoring and telemedicine constitute a subset of digita l health technologies that enable monitoring of patients outside conventional clinical settings, such as in the comfort of their own homes. Evidence regarding the efficacy, effectiveness, economics, and clinical preferences of remote patient monitoring and telemedicine is growing in many c...
Source: LANCET - July 14, 2017 Category: General Medicine Authors: Thomas A Ullman, Ashish Atreja Tags: Comment Source Type: research
Obituary Gordon Ostlere, alias Richard Gordon
Anaesthetist and author of the successful series of Doctor books. Born in London on Sept 15, 1921, he died after a stroke in Kent, UK, on Aug 11, 2017, aged 95 years.
Source: LANCET - September 8, 2017 Category: General Medicine Authors: Barbara Casassus Tags: Obituary Source Type: research
Articles Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study
High carbohydrate intake was associated with higher risk of total mortality, whereas total fat and individual types of fat were related to lower total mortality. Total fat and types of fat were not associated with cardiovascular disease, myocardial infarction, or cardiovascular disease mortality, whereas saturated fat had an inverse association with stroke. Global dietary guidelines should be reconsidered in light of these findings.
Source: LANCET - August 29, 2017 Category: General Medicine Authors: Mahshid Dehghan, Andrew Mente, Xiaohe Zhang, Sumathi Swaminathan, Wei Li, Viswanathan Mohan, Romaina Iqbal, Rajesh Kumar, Edelweiss Wentzel-Viljoen, Annika Rosengren, Leela Itty Amma, Alvaro Avezum, Jephat Chifamba, Rafael Diaz, Rasha Khatib, Scott Lear, Tags: Articles Source Type: research
Comment Hypertension in China: the gap between policy and practice
The high prevalence of hypertension in China is well known, with stroke being the most common cause of death and disability.1 Two large nationwide studies reported in The Lancet2,3 highlight that although the prevalence of hypertension in China is similar to that suggested in previous studies, it is simple deficiencies in the country's health system that make a large contribution to the disease burden. Both studies used data from the PEACE (Patient-Centred Evaluative Assessment of Cardiac Events) Million Persons Project (MPP), which enrolled 1 ·7 million adults aged 35–75 years from across China.
Source: LANCET - October 25, 2017 Category: General Medicine Authors: Therese Hesketh, Xudong Zhou Tags: Comment Source Type: research
Comment Physical activity lowers mortality and heart disease risks
In The Lancet, Scott A Lear and colleagues1 report results from a large cohort of 130 843 participants from 17 countries (including four low-income countries and seven middle-income countries) investigating the beneficial dose-dependent associations of all forms of physical activity with reduced mortality and cardiovascular disease risks.1 This is another confirmation that physica l activity has definite and dose-dependent benefits for lowering risks of all-cause mortality and cardiovascular disease (heart attacks, stroke, and heart failure).
Source: LANCET - September 21, 2017 Category: General Medicine Authors: Shifalika Goenka, I-Min Lee Tags: Comment Source Type: research
Comment Circadian rhythm and ischaemia –reperfusion injury
Every day, thousands of patients are exposed to ischaemia-reperfusion injury, either in uncontrolled circumstances (eg, acute myocardial infarction or ischaemic stroke) or under controlled conditions (eg, heart, kidney, or liver surgery, or transplantation). Whatever the clinical setting is, the extent of final tissue damage (ie, infarct size) is mainly determined by the duration of the ischaemic phase and the amount of jeopardised tissue.1 Experimental and proof-of-concept clinical trials have shown that infarct size results from the addition of an ischaemia-induced injury plus a reperfusion-induced injury, and that timel...
Source: LANCET - October 26, 2017 Category: General Medicine Authors: Thomas Bochaton, Michel Ovize Tags: Comment Source Type: research
Articles Drug-eluting stents in elderly patients with coronary artery disease (SENIOR): a randomised single-blind trial
Among elderly patients who have PCI, a DES and a short duration of DAPT are better than BMS and a similar duration of DAPT with respect to the occurrence of all-cause mortality, myocardial infarction, stroke, and ischaemia-driven target lesion revascularisation. A strategy of combination of a DES to reduce the risk of subsequent repeat revascularisations with a short BMS-like DAPT regimen to reduce the risk of bleeding event is an attractive option for elderly patients who have PCI.
Source: LANCET - November 1, 2017 Category: General Medicine Authors: Olivier Varenne, St éphane Cook, Georgios Sideris, Sasko Kedev, Thomas Cuisset, Didier Carrié, Thomas Hovasse, Philippe Garot, Rami El Mahmoud, Christian Spaulding, Gérard Helft, José F Diaz Fernandez, Salvatore Brugaletta, Eduardo Pinar-Bermudez, Jos Tags: Articles Source Type: research
