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Source: Korean J Hepatol
Infectious Disease: Hepatitis

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Total 4452 results found since Jan 2013.

A case of emphysematous hepatitis with spontaneous pneumoperitoneum in a patient with hilar cholangiocarcinoma
Korean J Hepatol. 2012 Mar;18(1):94-7. doi: 10.3350/kjhep.2012.18.1.94. Epub 2012 Mar 22.ABSTRACTAn 80-year-old woman with hilar cholangiocarcinoma was hospitalized due to sudden-onset abdominal pain. Computed tomography revealed hepatic necrosis accompanied with emphysematous change in the superior segment of the right liver (S7/S8), implying spontaneous rupture, based on the presence of perihepatic free air. Although urgent percutaneous drainage was performed, neither pus nor fluids were drained. These findings suggest emphysematous hepatitis with a hepatic mass. Despite the application of intensive care, the patient's c...
Source: Korean J Hepatol - April 19, 2012 Category: Gastroenterology Authors: Jung Ho Kim Eul Sik Jung Seok Hoo Jeong Ju Seung Kim Yang Suh Ku Ki Baik Hahm Ju Hyun Kim Yeon Suk Kim Source Type: research

Drug rash with eosinophilia and systemic symptoms syndrome following cholestatic hepatitis A: a case report
We describe a 22-year-old male who presented with acute kidney injury and was diagnosed with prolonged cholestatic hepatitis A. The patient also developed DRESS syndrome due to antibiotic and/or antiviral treatment. To our knowledge, this is the first report of histopathologically confirmed DRESS syndrome due to antibiotic and/or antiviral treatment following HAV infection with cholestatic features and renal injury.PMID:22511907 | PMC:PMC3326989 | DOI:10.3350/kjhep.2012.18.1.84
Source: Korean J Hepatol - April 19, 2012 Category: Gastroenterology Authors: Jihyun An Joo Ho Lee Hyojeong Lee Eunsil Yu Dan Bi Lee Ju Hyun Shim Sunyoung Yoon Yumi Lee Soeun Park Han Chu Lee Source Type: research

High efficacy of adefovir and entecavir combination therapy in patients with nucleoside-refractory hepatitis B
CONCLUSIONS: ADV+ETV combination therapy induced a good IVR in CHB patients who were refractory to more than 2 antiviral agents. This regimen may be a good alternative to TDF in Korea, where that drug is not available.PMID:22511906 | PMC:PMC3326991 | DOI:10.3350/kjhep.2012.18.1.75
Source: Korean J Hepatol - April 19, 2012 Category: Gastroenterology Authors: Hee Bok Chae Mee Jin Kim Eui Geun Seo Yong Hyeok Choi Hee Seung Lee Joung Ho Han Soon Man Yoon Seon Mee Park Sei Jin Youn Source Type: research

A case of emphysematous hepatitis with spontaneous pneumoperitoneum in a patient with hilar cholangiocarcinoma
Korean J Hepatol. 2012 Mar;18(1):94-7. doi: 10.3350/kjhep.2012.18.1.94. Epub 2012 Mar 22.ABSTRACTAn 80-year-old woman with hilar cholangiocarcinoma was hospitalized due to sudden-onset abdominal pain. Computed tomography revealed hepatic necrosis accompanied with emphysematous change in the superior segment of the right liver (S7/S8), implying spontaneous rupture, based on the presence of perihepatic free air. Although urgent percutaneous drainage was performed, neither pus nor fluids were drained. These findings suggest emphysematous hepatitis with a hepatic mass. Despite the application of intensive care, the patient's c...
Source: Korean J Hepatol - April 19, 2012 Category: Gastroenterology Authors: Jung Ho Kim Eul Sik Jung Seok Hoo Jeong Ju Seung Kim Yang Suh Ku Ki Baik Hahm Ju Hyun Kim Yeon Suk Kim Source Type: research

Optimal time for repeating the IgM anti-hepatitis A virus antibody test in acute hepatitis A patients with a negative initial test
CONCLUSIONS: The results of HAV tests were significantly associated with the interval from the peak-ALT day to the HAV-test day. The optimal time for repeating the HAV test in clinically suspicious AHA patients with a negative initial HAV test appears to be at least 2 days after the peak-ALT day.PMID:22511904 | PMC:PMC3326997 | DOI:10.3350/kjhep.2012.18.1.56
Source: Korean J Hepatol - April 19, 2012 Category: Gastroenterology Authors: Jong Jin Hyun Yeon Seok Seo Hyonggin An Sun Young Yim Min Ho Seo Hye Sook Kim Chang Ha Kim Ji Hoon Kim Bora Keum Yong Sik Kim Hyung Joon Yim Hong Sik Lee Soon Ho Um Chang Duck Kim Ho Sang Ryu Source Type: research

Rapid normalization of alanine aminotransferase predicts viral response during combined peginterferon and ribavirin treatment in chronic hepatitis C patients
CONCLUSIONS: The SVR rate is significantly associated with normalization, and especially rapid normalization of ALT. Rapid normalization of ALT by 4 weeks after treatment might be a useful response factor that is readily available in clinical practice, and especially for genotype 1 patients.PMID:22511902 | PMC:PMC3326992 | DOI:10.3350/kjhep.2012.18.1.41
Source: Korean J Hepatol - April 19, 2012 Category: Gastroenterology Authors: Yun Jung Kim Byoung Kuk Jang Eun Soo Kim Kyung Sik Park Kwang Bum Cho Woo Jin Chung Jae Seok Hwang Source Type: research

The effect of alanine aminotransferase dynamics on predicting sustained virological response in chronic hepatitis C virus infection
Korean J Hepatol. 2012 Mar;18(1):29-31. doi: 10.3350/kjhep.2012.18.1.29. Epub 2012 Mar 22.NO ABSTRACTPMID:22511900 | PMC:PMC3326988 | DOI:10.3350/kjhep.2012.18.1.29
Source: Korean J Hepatol - April 19, 2012 Category: Gastroenterology Authors: Tae Yeob Kim Source Type: research

Recent trends in the treatment of chronic hepatitis C
Korean J Hepatol. 2012 Mar;18(1):22-8. doi: 10.3350/kjhep.2012.18.1.22. Epub 2012 Mar 22.ABSTRACTPegylated interferon and ribavirin combination therapy is accepted as the standard antiviral treatment for chronic hepatitis C regardless of HCV genotype. This combination therapy achieves higher response rates than previous therapy, but, nevertheless, a large proportion of patients suffer from treatment failure or adverse events. Recent clinical studies of viral kinetics during antiviral treatment have led to the introduction of response-guided therapy, the concept of 'customized therapy depending on viral response', which foc...
Source: Korean J Hepatol - April 19, 2012 Category: Gastroenterology Authors: Dae Won Jun Won Young Tak Si Hyun Bae Youn Jae Lee Source Type: research

A case of emphysematous hepatitis with spontaneous pneumoperitoneum in a patient with hilar cholangiocarcinoma
Korean J Hepatol. 2012 Mar;18(1):94-7. doi: 10.3350/kjhep.2012.18.1.94. Epub 2012 Mar 22.ABSTRACTAn 80-year-old woman with hilar cholangiocarcinoma was hospitalized due to sudden-onset abdominal pain. Computed tomography revealed hepatic necrosis accompanied with emphysematous change in the superior segment of the right liver (S7/S8), implying spontaneous rupture, based on the presence of perihepatic free air. Although urgent percutaneous drainage was performed, neither pus nor fluids were drained. These findings suggest emphysematous hepatitis with a hepatic mass. Despite the application of intensive care, the patient's c...
Source: Korean J Hepatol - April 19, 2012 Category: Gastroenterology Authors: Jung Ho Kim Eul Sik Jung Seok Hoo Jeong Ju Seung Kim Yang Suh Ku Ki Baik Hahm Ju Hyun Kim Yeon Suk Kim Source Type: research

Drug rash with eosinophilia and systemic symptoms syndrome following cholestatic hepatitis A: a case report
We describe a 22-year-old male who presented with acute kidney injury and was diagnosed with prolonged cholestatic hepatitis A. The patient also developed DRESS syndrome due to antibiotic and/or antiviral treatment. To our knowledge, this is the first report of histopathologically confirmed DRESS syndrome due to antibiotic and/or antiviral treatment following HAV infection with cholestatic features and renal injury.PMID:22511907 | PMC:PMC3326989 | DOI:10.3350/kjhep.2012.18.1.84
Source: Korean J Hepatol - April 19, 2012 Category: Gastroenterology Authors: Jihyun An Joo Ho Lee Hyojeong Lee Eunsil Yu Dan Bi Lee Ju Hyun Shim Sunyoung Yoon Yumi Lee Soeun Park Han Chu Lee Source Type: research

High efficacy of adefovir and entecavir combination therapy in patients with nucleoside-refractory hepatitis B
CONCLUSIONS: ADV+ETV combination therapy induced a good IVR in CHB patients who were refractory to more than 2 antiviral agents. This regimen may be a good alternative to TDF in Korea, where that drug is not available.PMID:22511906 | PMC:PMC3326991 | DOI:10.3350/kjhep.2012.18.1.75
Source: Korean J Hepatol - April 19, 2012 Category: Gastroenterology Authors: Hee Bok Chae Mee Jin Kim Eui Geun Seo Yong Hyeok Choi Hee Seung Lee Joung Ho Han Soon Man Yoon Seon Mee Park Sei Jin Youn Source Type: research

Optimal time for repeating the IgM anti-hepatitis A virus antibody test in acute hepatitis A patients with a negative initial test
CONCLUSIONS: The results of HAV tests were significantly associated with the interval from the peak-ALT day to the HAV-test day. The optimal time for repeating the HAV test in clinically suspicious AHA patients with a negative initial HAV test appears to be at least 2 days after the peak-ALT day.PMID:22511904 | PMC:PMC3326997 | DOI:10.3350/kjhep.2012.18.1.56
Source: Korean J Hepatol - April 19, 2012 Category: Gastroenterology Authors: Jong Jin Hyun Yeon Seok Seo Hyonggin An Sun Young Yim Min Ho Seo Hye Sook Kim Chang Ha Kim Ji Hoon Kim Bora Keum Yong Sik Kim Hyung Joon Yim Hong Sik Lee Soon Ho Um Chang Duck Kim Ho Sang Ryu Source Type: research

Rapid normalization of alanine aminotransferase predicts viral response during combined peginterferon and ribavirin treatment in chronic hepatitis C patients
CONCLUSIONS: The SVR rate is significantly associated with normalization, and especially rapid normalization of ALT. Rapid normalization of ALT by 4 weeks after treatment might be a useful response factor that is readily available in clinical practice, and especially for genotype 1 patients.PMID:22511902 | PMC:PMC3326992 | DOI:10.3350/kjhep.2012.18.1.41
Source: Korean J Hepatol - April 19, 2012 Category: Gastroenterology Authors: Yun Jung Kim Byoung Kuk Jang Eun Soo Kim Kyung Sik Park Kwang Bum Cho Woo Jin Chung Jae Seok Hwang Source Type: research

The effect of alanine aminotransferase dynamics on predicting sustained virological response in chronic hepatitis C virus infection
Korean J Hepatol. 2012 Mar;18(1):29-31. doi: 10.3350/kjhep.2012.18.1.29. Epub 2012 Mar 22.NO ABSTRACTPMID:22511900 | PMC:PMC3326988 | DOI:10.3350/kjhep.2012.18.1.29
Source: Korean J Hepatol - April 19, 2012 Category: Gastroenterology Authors: Tae Yeob Kim Source Type: research

Recent trends in the treatment of chronic hepatitis C
Korean J Hepatol. 2012 Mar;18(1):22-8. doi: 10.3350/kjhep.2012.18.1.22. Epub 2012 Mar 22.ABSTRACTPegylated interferon and ribavirin combination therapy is accepted as the standard antiviral treatment for chronic hepatitis C regardless of HCV genotype. This combination therapy achieves higher response rates than previous therapy, but, nevertheless, a large proportion of patients suffer from treatment failure or adverse events. Recent clinical studies of viral kinetics during antiviral treatment have led to the introduction of response-guided therapy, the concept of 'customized therapy depending on viral response', which foc...
Source: Korean J Hepatol - April 19, 2012 Category: Gastroenterology Authors: Dae Won Jun Won Young Tak Si Hyun Bae Youn Jae Lee Source Type: research