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Cardiac myxomas: clinical presentation, diagnosis and management
Cardiac myxomas (CM) are the most common type of primary cardiac tumours in adults, which have an approximate incidence of up to 0.2% in some autopsy series. The purpose of this review is to summarise the literature on CM, including clinical presentation, differential diagnosis, work-up including imaging modalities and histopathology, management, and prognosis. CM are benign neoplasms developed from multipotent mesenchyme and usually present as an undifferentiated atrial mass. They are typically pedunculated and attached at the fossa ovalis, on the left side of the atrial septum. Potentially life-threatening, the presence ...
Source: Heart - May 12, 2022 Category: Cardiology Authors: Griborio-Guzman, A. G., Aseyev, O. I., Shah, H., Sadreddini, M. Tags: Review articles Reviews Source Type: research

Cardiovascular highlights from non-cardiology journals
Continuous positive airway pressure fails to improve cardiovascular outcomes in obstructive sleep apnea Obstructive sleep apnea (OSA) is associated with increased cardiovascular events in observational studies. Randomized trials have demonstrated continuous positive airway pressure (CPAP) therapy reduces blood pressure, markers of oxidative stress and insulin insensitivity. Yet, it remains unclear whether treatment with CPAP reduces cardiovascular events. In the largest study of its kind, 2717 patients aged 45 to 75 years with moderate-to-severe OSA and coronary or cerebrovascular disease were randomized in open-label fash...
Source: Heart - March 12, 2017 Category: Cardiology Authors: McCabe, J. M. Tags: Journal scan Source Type: research

Beyond Framingham risk factors and coronary calcification: does aortic valve calcification improve risk prediction? The Heinz Nixdorf Recall Study
Conclusions AVC is associated with incident coronary and CVD events independent of Framingham risk factors. However, AVC fails to improve cardiovascular event prediction over Framingham risk factors and CAC.
Source: Heart - May 19, 2014 Category: Cardiology Authors: Kalsch, H., Lehmann, N., Mahabadi, A. A., Bauer, M., Kara, K., Huppe, P., Moebus, S., Mohlenkamp, S., Dragano, N., Schmermund, A., Stang, A., Jockel, K.-H., Erbel, R., on behalf of the Investigator Group of the Heinz Nixdorf Recall Study Tags: Drugs: cardiovascular system, Clinical diagnostic tests Cardiac risk factors and prevention Source Type: research

Cardiovascular highlights from non-cardiology journals
Estrogen formulations have differing cardiovascular risk profile Ever since the publication of the Women's Health Initiative randomized trial that demonstrated clinical harm associated with use of conjugated equine estrogens, providers have been left in a challenging position in balancing the risk of these therapies against their benefit in treatment of menopausal symptoms. In the present study, the authors examined cardiac safety of oral conjugated equine estrogen vs. oral estradiol in a population-based case control study of post-menopausal women. Cases of venous thrombosis (n=68), myocardial infarction (n=67) or ischemi...
Source: Heart - May 19, 2014 Category: Cardiology Authors: Bradley, S. M. Tags: Journal scan Source Type: research

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