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Minimally invasive mitral valve surgery without aortic cross-clamping and with femoral cannulation is not associated with increased risk of stroke compared with traditional mitral valve surgery: a propensity score-matched analysis ADULT CARDIAC
CONCLUSIONS A minimally invasive approach for mitral valve surgery on a fibrillating heart was not associated with a greater incidence of stroke/TIA than was median sternotomy. When performed by highly experienced surgeons, the minimally invasive approach with fibrillatory arrest did not increase the risk of perioperative stroke.
Source: European Journal of Cardio-Thoracic Surgery - November 17, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Ad, N., Holmes, S. D., Shuman, D. J., Pritchard, G., Massimiano, P. S. Tags: Transplantation - heart, Basic research vascular ADULT CARDIAC Source Type: research

A modified Glenn shunt reduces right ventricular stroke work during left ventricular assist device therapy TRANSPLANTATION AND MECHANICAL CIRCULATORY SUPPORT
CONCLUSIONS A modified Glenn shunt reduced RV volumes, RV stroke work and RA pressure during LVAD therapy in an experimental model of heart failure in pigs.
Source: European Journal of Cardio-Thoracic Surgery - February 6, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Schiller, P., Vikholm, P., Hellgren, L. Tags: Coronary disease, Myocardial protection, Peripheral vascular TRANSPLANTATION AND MECHANICAL CIRCULATORY SUPPORT Source Type: research

Safety and efficacy of miniaturized extracorporeal circulation when compared with off-pump and conventional coronary artery bypass grafting: evidence synthesis from a comprehensive Bayesian-framework network meta-analysis of 134 randomized controlled trials involving 22 778 patients ADULT CARDIAC
CONCLUSIONS MECC and OPCAB both improve perioperative outcomes following coronary bypass surgery when compared with conventional CABG performed with extracorporeal circulation. MECC may represent an attractive compromise between OPCAB and CECC.
Source: European Journal of Cardio-Thoracic Surgery - April 28, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Kowalewski, M., Pawliszak, W., Raffa, G. M., Malvindi, P. G., Kowalkowska, M. E., Zaborowska, K., Kowalewski, J., Tarelli, G., Taggart, D. P., Anisimowicz, L. Tags: Molecular biology, History, Myocardial protection, Peripheral vascular, Transplantation - heart ADULT CARDIAC Source Type: research

Aortic arch reoperation in a single centre: early and late results in 57 consecutive patients AORTIC SURGERY
CONCLUSIONS Aortic arch reoperation, although a technically complex operation, can be performed with acceptable mortality and morbidity. Patients with aortic dissection during their previous operation required repeat surgery significantly earlier when compared with patients with arch aneurysms, and had worse long-term survival.
Source: European Journal of Cardio-Thoracic Surgery - June 13, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Moz, M., Misfeld, M., Leontyev, S., Borger, M. A., Davierwala, P., Mohr, F.-W. Tags: AORTIC SURGERY Source Type: research

Maze surgery normalizes left ventricular function in patients with persistent lone atrial fibrillation ADULT CARDIAC
CONCLUSIONS Within a dedicated AF centre, maze surgery grants excellent outcomes, with symptoms relief and negligible risk. It provides a complete reversal of arrhythmia-related myocardial dysfunction and is therefore a convenient alternative to His bundle ablation and lifelong pacemaker dependency in symptomatic refractory patients.
Source: European Journal of Cardio-Thoracic Surgery - October 10, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Pozzoli, A., Taramasso, M., Coppola, G., Kamami, M., La Canna, G., Bella, P. D., Alfieri, O., Benussi, S. Tags: Minimally invasive surgery, Myocardial infarction, Myocardial protection, Transplantation - heart ADULT CARDIAC Source Type: research

First experience without pre-ballooning in transapical aortic valve implantation: a propensity score-matched analysis ADULT CARDIAC
CONCLUSIONS Direct TA implantation of the SAPIEN valve without pre-ballooning is feasible, safe, does not seem to compromise functional outcomes and may be associated with fewer neurological events.
Source: European Journal of Cardio-Thoracic Surgery - December 11, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Kempfert, J., Meyer, A., Kim, W.-K., van Linden, A., Arsalan, M., Blumenstein, J., Mollmann, H., Walther, T. Tags: Transplantation - heart, Basic research vascular ADULT CARDIAC Source Type: research

Single-centre experience with next-generation devices for transapical aortic valve implantation ADULT CARDIAC
CONCLUSIONS In a real-world clinical setting, next-generation transapical THV yielded positive haemodynamic results. The incidence of relevant paravalvular regurgitation was scarce in this group and clinical outcomes were encouraging during short-term follow-up. Long-term follow-up is required to investigate the durability of these new devices.
Source: European Journal of Cardio-Thoracic Surgery - December 11, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Seiffert, M., Conradi, L., Kloth, B., Koschyk, D., Schirmer, J., Schnabel, R. B., Blankenberg, S., Reichenspurner, H., Diemert, P., Treede, H. Tags: Electrophysiology - arrhythmias, Transplantation - heart, Basic research vascular ADULT CARDIAC Source Type: research

A comparison of aortic valve replacement via an anterior right minithoracotomy with standard sternotomy: a propensity score analysis of 492 patients ADULT CARDIAC
CONCLUSION Minimally invasive AVR via an anterior right thoracotomy with predominately central cannulation can be performed with morbidity and mortality similar to that of a sternotomy approach. There appear to be advantages to this minimally invasive approach when compared with sternotomy in terms of less intraoperative blood product usage, lower wound infection rates and decreased hospital stays. If mortality and the occurrence of adverse events are taken together, MIAVR may be associated with better outcomes. As minimally invasive AVR becomes more common, further long-term follow-up is needed and a prospective multicent...
Source: European Journal of Cardio-Thoracic Surgery - January 13, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Bowdish, M. E., Hui, D. S., Cleveland, J. D., Mack, W. J., Sinha, R., Ranjan, R., Cohen, R. G., Baker, C. J., Cunningham, M. J., Barr, M. L., Starnes, V. A. Tags: Transplantation - heart, Basic research vascular ADULT CARDIAC Source Type: research

Ten-year outcomes of Fontan conversion in Australia and New Zealand demonstrate the superiority of a strategy of early conversion CONGENITAL
CONCLUSIONS Fontan conversion is associated with lasting survival outcomes up to 10 years after conversion. A strategy of surgical conversion at earlier stage of failure may be associated with better survival free from transplantation.
Source: European Journal of Cardio-Thoracic Surgery - January 13, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Poh, C. L., Cochrane, A., Galati, J. C., Bullock, A., Celermajer, D. S., Gentles, T., du Plessis, K., Winlaw, D. S., Hornung, T., Finucane, K., d'Udekem, Y. Tags: Cardiac - other CONGENITAL Source Type: research

Minimally invasive aortic valve replacement with a sutureless valve through a right anterior mini-thoracotomy versus transcatheter aortic valve implantation in high-risk patients ADULT CARDIAC
CONCLUSIONS Minimally invasive aortic valve replacement with perceval S sutureless valves through an RT is associated with a trend of better early outcomes and mid-term survival compared with TAVI.
Source: European Journal of Cardio-Thoracic Surgery - February 6, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Miceli, A., Gilmanov, D., Murzi, M., Marchi, F., Ferrarini, M., Cerillo, A. G., Quaini, E., Solinas, M., Berti, S., Glauber, M. Tags: Transplantation - heart, Basic research vascular ADULT CARDIAC Source Type: research

Current evidence of coronary artery bypass grafting off-pump versus on-pump: a systematic review with meta-analysis of over 16 900 patients investigated in randomized controlled trials REVIEWS
In the present systematic review with meta-analysis, we sought to determine the current strength of evidence for or against off-pump and on-pump coronary artery bypass grafting (CABG) with regard to hard clinical end-points, graft patency and cost-effectiveness. We performed a meta-analysis of only randomized controlled trials (RCT) which reported at least one of the desired end-points including: (i) major adverse cardiac and cerebrovascular events (MACCE), (ii) all-cause mortality, (iii) myocardial infarction, (iv) cerebrovascular accident, (v) repeat revascularization, (vi) graft patency and (vii) cost-effectiveness. The...
Source: European Journal of Cardio-Thoracic Surgery - March 16, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Deppe, A.-C., Arbash, W., Kuhn, E. W., Slottosch, I., Scherner, M., Liakopoulos, O. J., Choi, Y.-H., Wahlers, T. Tags: Molecular biology, Transplantation - heart REVIEWS Source Type: research

Improving outcomes: case-matched comparison of novel second-generation versus first-generation self-expandable transcatheter heart valves ADULT CARDIAC
DISCUSSION TF-TAVI was feasible and safe using this new type of nitinol-based THV. Superiority to the current generation of self-expanding THVs was achieved regarding post-interventional pressure gradients and EOA, severity of residual PVL and rate of PM implantation. Results set a promising quality standard for TF-TAVI with a self-expanding THV, but will have to be confirmed in a larger patient cohorts for further clinical evaluation.
Source: European Journal of Cardio-Thoracic Surgery - July 19, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Schaefer, A., Treede, H., Schoen, G., Deuschl, F., Schofer, N., Schneeberger, Y., Blankenberg, S., Reichenspurner, H., Schaefer, U., Conradi, L. Tags: History, Transplantation - heart, Basic research vascular ADULT CARDIAC Source Type: research

Haemodynamic benefits of rapid deployment aortic valve replacement via a minimally invasive approach: 1-year results of a prospective multicentre randomized controlled trial ADULT CARDIAC
CONCLUSIONS MIS-RDAVR is associated with a significantly reduced cross-clamp time and better valvular haemodynamic function than FS-AVR. However, paravalvular leak rates are higher with MIS-RDAVR.
Source: European Journal of Cardio-Thoracic Surgery - October 4, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Borger, M. A., Dohmen, P. M., Knosalla, C., Hammerschmidt, R., Merk, D. R., Richter, M., Doenst, T., Conradi, L., Treede, H., Moustafine, V., Holzhey, D. M., Duhay, F., Strauch, J. Tags: Transplantation - heart, Basic research vascular ADULT CARDIAC Source Type: research

Evaluation of the HeartWare ventricular assist device Lavare cycle in a particle image velocimetry model and in clinical practice TX & MCS
CONCLUSIONS The Lavare cycle effectively generates ventricular washout and the adverse event profiles of ReVOLVE patients with the Lavare cycle on were better than those with the Lavare cycle off. Larger studies are warranted to verify the positive effect of the Lavare cycle and to optimize speed modulation settings, so additional clinically relevant improvements can be realized.
Source: European Journal of Cardio-Thoracic Surgery - November 3, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Zimpfer, D., Strueber, M., Aigner, P., Schmitto, J. D., Fiane, A. E., Larbalestier, R., Tsui, S., Jansz, P., Simon, A., Schueler, S., Moscato, F., Schima, H. Tags: Peripheral vascular TX & amp; MCS Source Type: research