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Specialty: Internal Medicine
Source: Annals of Internal Medicine

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Total 404 results found since Jan 2013.

Comparative Safety Analysis of Oral Antipsychotics for In-Hospital Adverse Clinical Events in Older Adults After Major Surgery : A Nationwide Cohort Study
CONCLUSION: These results suggest that atypical antipsychotics and haloperidol have similar rates of in-hospital adverse clinical events in older patients with postoperative delirium who receive an oral low-to-moderate dose antipsychotic drug.PRIMARY FUNDING SOURCE: National Institute on Aging.PMID:37665998 | DOI:10.7326/M22-3021
Source: Annals of Internal Medicine - September 4, 2023 Category: Internal Medicine Authors: Dae Hyun Kim Su Been Lee Chan Mi Park Raisa Levin Eran Metzger Brian T Bateman E Wesley Ely Pratik P Pandharipande Margaret A Pisani Richard N Jones Edward R Marcantonio Sharon K Inouye Source Type: research

Selective d-Dimer Testing for Diagnosis of a First Suspected Episode of Deep Venous Thrombosis: A Randomized Trial.
CONCLUSION: A selective d-dimer testing strategy seems as safe as and more efficient than having everyone undergo d-dimer testing when diagnosing a first episode of suspected DVT. PRIMARY FUNDING SOURCE: Heart and Stroke Foundation of Ontario. PMID: 23318311 [PubMed - in process]
Source: Annals of Internal Medicine - January 15, 2013 Category: Internal Medicine Authors: Linkins LA, Bates SM, Lang E, Kahn SR, Douketis JD, Julian J, Parpia S, Gross P, Weitz JI, Spencer FA, Lee AY, O'Donnell MJ, Crowther MA, Chan HH, Lim W, Schulman S, Ginsberg JS, Kearon C Tags: Ann Intern Med Source Type: research

Adverse Effects Associated With Transcatheter Aortic Valve Implantation: A Meta-analysis of Contemporary Studies.
CONCLUSION: The most common adverse effects associated with TAVI are heart block, vascular complications, and renal failure. The type of transcatheter valve and the route of implantation are associated with observed variations in the risks for some adverse effects. PRIMARY FUNDING SOURCE: Heart and Stroke Foundation of Canada. PMID: 23277899 [PubMed - in process]
Source: Annals of Internal Medicine - January 1, 2013 Category: Internal Medicine Authors: Khatri PJ, Webb JG, Rodés-Cabau J, Fremes SE, Ruel M, Lau K, Guo H, Wijeysundera HC, Ko DT Tags: Ann Intern Med Source Type: research

Review: Cholinesterase inhibitors do not reduce progression to dementia from mild cognitive impairment.
CONCLUSION In adults with mild cognitive impairment, cholinesterase inhibitors do not differ from placebo for progression to dementia at 1 and 3 years but increase nonserious adverse events.Cholinesterase inhibitors (ChEIs) vs placebo in adults with mild cognitive impairment*OutcomesNumber of trials (n)Weighted event ratesAt 16 wk to 3 yChEIsPlaceboRRR (95% CI)NNT (CI)Dementia at 1 y3 (2560)7.6%12%31% (0 to 53)NSDementia at 2 y2 (2048)12%18%33% (17 to 45)17 (12 to 34)Dementia at 3 y2 (1530)20%24%16% (-2 to 30)NSSerious adverse events6 (4207)19%19%3% (-10 to 14)NSRRI (CI)NNH (CI)Any adverse event6 (4207)89%82%9% (2 to 16)15...
Source: Annals of Internal Medicine - February 19, 2013 Category: Internal Medicine Authors: Masoodi N Tags: Ann Intern Med Source Type: research

Management of Obstructive Sleep Apnea in Adults: A Clinical Practice Guideline From the American College of Physicians.
Abstract DESCRIPTION: The American College of Physicians (ACP) developed this guideline to present the evidence and provide clinical recommendations on the management of obstructive sleep apnea (OSA) in adults. METHODS: This guideline is based on published literature from 1966 to September 2010 that was identified by using MEDLINE, the Cochrane Central Register of Controlled Trials, and the Cochrane Database of Systematic Reviews. A supplemental MEDLINE search identified additional articles through October 2012. Searches were limited to English-language publications. The clinical outcomes evaluated for this g...
Source: Annals of Internal Medicine - September 24, 2013 Category: Internal Medicine Authors: Qaseem A, Holty JE, Owens DK, Dallas P, Starkey M, Shekelle P, for the Clinical Guidelines Committee of the American College of Physicians Tags: Ann Intern Med Source Type: research

Screening, Monitoring, and Treatment of Stage 1 to 3 Chronic Kidney Disease: A Clinical Practice Guideline From the Clinical Guidelines Committee of the American College of Physicians.
Abstract DESCRIPTION: The American College of Physicians (ACP) developed this guideline to present the evidence and provide clinical recommendations on the screening, monitoring, and treatment of adults with stage 1 to 3 chronic kidney disease. METHODS: This guideline is based on a systematic evidence review evaluating the published literature on this topic from 1985 through November 2011 that was identified by using MEDLINE and the Cochrane Database of Systematic Reviews. Searches were limited to English-language publications. The clinical outcomes evaluated for this guideline included all-cause mortality, c...
Source: Annals of Internal Medicine - October 22, 2013 Category: Internal Medicine Authors: Qaseem A, Hopkins RH, Sweet DE, Starkey M, Shekelle P Tags: Ann Intern Med Source Type: research

Rate- and rhythm-control therapies in patients with atrial fibrillation: a systematic review.
CONCLUSION: Pharmacologic rate- and rhythm-control strategies have comparable efficacy across outcomes in primarily older patients with mild AF symptoms. Pulmonary vein isolation is better than antiarrhythmic medications at reducing recurrences of AF in younger patients with paroxysmal AF and mild structural heart disease. Future research should address uncertainties related to subgroups of interest and the effect of different therapies on long-term clinical outcomes. PRIMARY FUNDING SOURCE: Agency for Healthcare Research and Quality. PMID: 24887617 [PubMed - in process]
Source: Annals of Internal Medicine - June 3, 2014 Category: Internal Medicine Authors: Al-Khatib SM, Allen LaPointe NM, Chatterjee R, Crowley MJ, Dupre ME, Kong DF, Lopes RD, Povsic TJ, Raju SS, Shah B, Kosinski AS, McBroom AJ, Sanders GD Tags: Ann Intern Med Source Type: research

Screening for Asymptomatic Carotid Artery Stenosis: U.S. Preventive Services Task Force Recommendation Statement.
Abstract Description: Update of the 2007 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for carotid artery stenosis. Methods: The USPSTF commissioned a systematic review to synthesize the evidence on the accuracy of screening tests, externally validated risk stratification tools, the benefits of treatment of asymptomatic carotid artery stenosis with carotid endarterectomy (CEA) or carotid angioplasty and stenting (CAAS), the benefits from medications added to current standard medical therapy, and the harms of screening and treatment with CEA or CAAS. Population: This recommendat...
Source: Annals of Internal Medicine - July 8, 2014 Category: Internal Medicine Authors: LeFevre ML Tags: Ann Intern Med Source Type: research

Diagnosis of obstructive sleep apnea in adults: a clinical practice guideline from the american college of physicians.
Abstract DESCRIPTION: The American College of Physicians (ACP) developed this guideline to present the evidence and provide clinical recommendations on the diagnosis of obstructive sleep apnea in adults. METHODS: This guideline is based on published literature on this topic that was identified by using MEDLINE (1966 through May 2013), the Cochrane Central Register of Controlled Trials, and the Cochrane Database of Systematic Reviews. Searches were limited to English-language publications. The clinical outcomes evaluated for this guideline included all-cause mortality, cardiovascular mortality, nonfatal cardio...
Source: Annals of Internal Medicine - August 5, 2014 Category: Internal Medicine Authors: Qaseem A, Dallas P, Owens DK, Starkey M, Holty JE, Shekelle P, Clinical Guidelines Committee of the American College of Physicians Tags: Ann Intern Med Source Type: research

Comparative effectiveness of generic and brand-name statins on patient outcomes: a cohort study.
CONCLUSION: Compared with those initiating brand-name statins, patients initiating generic statins were more likely to adhere and had a lower rate of a composite clinical outcome. PRIMARY FUNDING SOURCE: Teva Pharmaceuticals. PMID: 25222387 [PubMed - in process]
Source: Annals of Internal Medicine - September 16, 2014 Category: Internal Medicine Authors: Gagne JJ, Choudhry NK, Kesselheim AS, Polinski JM, Hutchins D, Matlin OS, Brennan TA, Avorn J, Shrank WH Tags: Ann Intern Med Source Type: research

Effects of Blood Pressure Reduction in Mild Hypertension: A Systematic Review and Meta-analysis.
Conclusion: Blood pressure-lowering therapy is likely to prevent stroke and death in patients with uncomplicated grade 1 hypertension. Primary Funding Source: Swedish Heart-Lung Foundation, Swedish Research Council, Australian Research Council, and National Health and Medical Research Council of Australia. PMID: 25531552 [PubMed - as supplied by publisher]
Source: Annals of Internal Medicine - December 23, 2014 Category: Internal Medicine Authors: Sundström J, Arima H, Jackson R, Turnbull F, Rahimi K, Chalmers J, Woodward M, Neal B, on behalf of the Blood Pressure Lowering Treatment Trialists' Collaboration* Tags: Ann Intern Med Source Type: research

National Institutes of Health Pathways to Prevention Workshop: The Role of Opioids in the Treatment of Chronic Pain.
This article is an abridged version of the panel's report, the full version of which is available at at https://prevention.nih.gov/programs-events/pathways-to-prevention/workshops/opioids-chronic-pain/workshop-resources#finalreport. PMID: 25581341 [PubMed - as supplied by publisher]
Source: Annals of Internal Medicine - January 13, 2015 Category: Internal Medicine Authors: Reuben DB, H Alvanzo AA, Ashikaga T, Bogat GA, Callahan CM, Ruffing V, Steffens DC Tags: Ann Intern Med Source Type: research

Calibration of the Pooled Cohort Equations for Atherosclerotic Cardiovascular Disease: An Update.
Abstract The latest guidelines from the American College of Cardiology and American Heart Association, released in fall 2013, provide a long-anticipated update to the recommendations of the Third Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). The guidelines incorporate a new risk score for atherosclerotic cardiovascular disease that includes stroke as well as coronary heart disease. After publication, the new pooled cohort equations (PCEs) were evaluated in 15 studies from the United States a...
Source: Annals of Internal Medicine - October 10, 2016 Category: Internal Medicine Authors: Cook NR, Ridker PM Tags: Ann Intern Med Source Type: research

Association of Coffee Consumption With Total and Cause-Specific Mortality Among Nonwhite Populations.
Conclusion: Higher consumption of coffee was associated with lower risk for death in African Americans, Japanese Americans, Latinos, and whites. Primary Funding Source: National Cancer Institute. PMID: 28693036 [PubMed - as supplied by publisher]
Source: Annals of Internal Medicine - July 11, 2017 Category: Internal Medicine Authors: Park SY, Freedman ND, Haiman CA, Le Marchand L, Wilkens LR, Setiawan VW Tags: Ann Intern Med Source Type: research