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One‐Year Mortality in Elderly Adults with Non‐ST‐Elevation Acute Coronary Syndrome: Effect of Diabetic Status and Admission Hyperglycemia
ConclusionIn elderly adults with NSTEACS, diabetes mellitus and hyperglycemia on admission are associated with higher mortality, mostly because of preexisting cardiovascular and renal damage.
Source: Journal of the American Geriatrics Society - June 10, 2014 Category: Geriatrics Authors: Stefano Savonitto, Nuccia Morici, Claudio Cavallini, Roberto Antonicelli, Anna Sonia Petronio, Ernesto Murena, Zoran Olivari, Giuseppe Steffenino, Francesco Bonechi, Antonio Mafrici, Anna Toso, Federico Piscione, Leonardo Bolognese, Stefano De Servi Tags: Clinical Investigations Source Type: research

New Oral Anticoagulants in Elderly Adults: Evidence from a Meta‐Analysis of Randomized Trials
ConclusionIn participants of clinical trials aged 75 and older, NOACs did not cause excess bleeding and were associated with equal or greater efficacy than conventional therapy.
Source: Journal of the American Geriatrics Society - May 1, 2014 Category: Geriatrics Authors: Partha Sardar, Saurav Chatterjee, Shobhana Chaudhari, Gregory Y. H. Lip Tags: Clinical Investigations Source Type: research

Sleep Duration in Midlife and Later Life in Relation to Cognition
ConclusionExtreme sleep durations at midlife and later life and extreme changes in sleep duration over time appear to be associated with poor cognition in older women.
Source: Journal of the American Geriatrics Society - May 1, 2014 Category: Geriatrics Authors: Elizabeth E. Devore, Francine Grodstein, Jeanne F. Duffy, Meir J. Stampfer, Charles A. Czeisler, Eva S. Schernhammer Tags: Clinical Investigations Source Type: research

Physical Activity in Older Men: Longitudinal Associations with Inflammatory and Hemostatic Biomarkers, N‐Terminal Pro‐Brain Natriuretic Peptide, and Onset of Coronary Heart Disease and Mortality
ConclusionEven light PA was associated with significantly lower risk of CHD events in healthy older men, partly through inflammatory and hemostatic mechanisms and cardiac function (NT‐proBNP).
Source: Journal of the American Geriatrics Society - March 17, 2014 Category: Geriatrics Authors: Barbara J. Jefferis, Peter H. Whincup, Lucy T. Lennon, Olia Papacosta, S. Goya Wannamethee Tags: Clinical Investigations Source Type: research

Delirium Risk Prediction, Healthcare Use and Mortality of Elderly Adults in the Emergency Department
ConclusionThis risk prediction rule may help identify a group of individuals in the ED at high risk of developing delirium who should undergo screening, but it requires external validation. Identification of delirium in the ED may enable physicians to implement strategies to decrease delirium duration and avoid inappropriate discharge of individuals with acute delirium, improving outcomes.
Source: Journal of the American Geriatrics Society - February 10, 2014 Category: Geriatrics Authors: Maura Kennedy, Richard A. Enander, Sarah P. Tadiri, Richard E. Wolfe, Nathan I. Shapiro, Edward R. Marcantonio Tags: Clinical Investigations Source Type: research

Association Between Higher Plasma Lutein, Zeaxanthin, and Vitamin C Concentrations and Longer Telomere Length: Results of the Austrian Stroke Prevention Study
ConclusionThis study provides first evidence that higher lutein, zeaxanthin, and vitamin C concentrations in plasma are associated with longer LTL in normal elderly persons and suggest a protective role of these vitamins in telomere maintenance.
Source: Journal of the American Geriatrics Society - January 15, 2014 Category: Geriatrics Authors: Abhijit Sen, Gunther Marsche, Paul Freudenberger, Michael Schallert, Anna M. Toeglhofer, Christoph Nagl, Reinhold Schmidt, Lenore J. Launer, Helena Schmidt Tags: Clinical Investigations Source Type: research

Ageism in Interventional Stroke Studies
Source: Journal of the American Geriatrics Society - November 12, 2013 Category: Geriatrics Authors: Adriana Hadbavna, Desmond O'Neill Tags: Letters to the Editor Source Type: research

Tea Consumption and Depressive Symptoms in Older People in Rural China
ConclusionsDaily tea consumption is associated with a lower likelihood of depressive symptoms in Chinese older people living in a rural community. The association appears to be independent of cerebrovascular disease and atherosclerosis.
Source: Journal of the American Geriatrics Society - October 1, 2013 Category: Geriatrics Authors: Lei Feng, Zhongrui Yan, Binglun Sun, Chuanzhu Cai, Hui Jiang, Ee‐Heok Kua, Tze‐Pin Ng, Chengxuan Qiu Tags: Brief Reports Source Type: research

Stroke Prevention in Atrial Fibrillation in Older Adults: Existing Knowledge Gaps and Areas for Innovation: A Summary of an American Federation for Aging Research Seminar
This article summarizes the meeting discussion and emphasizes innovative topic areas that may ultimately facilitate the application of novel preventive, diagnostic, and therapeutic insights into the management of older adults with AF. The opinions of those that participated in the meeting limit this report, which may not represent all of the questions that other experts in this field might raise.
Source: Journal of the American Geriatrics Society - September 19, 2013 Category: Geriatrics Authors: Steven A. Lubitz, Kenneth A. Bauer, Emelia J. Benjamin, Richard W. Besdine, Daniel E. Forman, Mahmut E. Gurol, Vivek Y. Reddy, Daniel E. Singer Tags: Special Articles Source Type: research

Advancing Age and 30‐Day Adverse Outcomes After Nonemergent General Surgeries
ConclusionThirty‐day mortality and complication and FTR rates increase with age after nonemergent general surgeries. Individuals aged 80 and older have especially high mortality after renal, cardiovascular, and pulmonary complications. Surgeons need to be more selective with advancing age regarding who will benefit from the surgical intervention.
Source: Journal of the American Geriatrics Society - August 8, 2013 Category: Geriatrics Authors: Csaba Gajdos, Deidre Kile, Mary T. Hawn, Emily Finlayson, William G. Henderson, Thomas N. Robinson Tags: Aging & Surgery Source Type: research

Prestroke Factors Associated with Poststroke Mortality and Recovery in Older Women in the Women's Health Initiative
ConclusionPotentially modifiable factors before stroke, including smoking, diabetes mellitus, and being underweight, were associated with greater poststroke mortality in older women. Being overweight or obese and physical activity before stroke were associated with lower poststroke mortality in older women.
Source: Journal of the American Geriatrics Society - July 19, 2013 Category: Geriatrics Authors: Christina L. Bell, Andrea LaCroix, Kamal Masaki, Erinn M. Hade, Todd Manini, W. Jerry Mysiw, Jess David Curb, Sylvia Wassertheil‐Smoller Tags: Brief Reports Source Type: research

Gamma‐Glutamyltransferase Predicts Functional Impairment in Elderly Adults After Ischemic Stroke
Source: Journal of the American Geriatrics Society - June 14, 2013 Category: Geriatrics Authors: Daniele D'Ambrosio, Gaetano Gargiulo, David Della‐Morte, Ferdinando Gallucci, Generoso Uomo, Tatjana Rundek, Pasquale Abete Tags: Letters to the Editor Source Type: research

The Timing Hypothesis and Hormone Replacement Therapy: A Paradigm Shift in the Primary Prevention of Coronary Heart Disease in Women. Part 2: Comparative Risks
A major misperception concerning postmenopausal hormone replacement therapy (HRT) is that the associated risks are large in magnitude and unique to HRT, but over the past 10 years, sufficient data have accumulated so that the magnitude and perspective of risks associated with the primary coronary heart disease prevention therapies of statins, aspirin, and postmenopausal HRT have become more fully defined. Review of randomized controlled trials indicates that the risks of primary prevention therapies and other medications commonly used in women's health are of similar type and magnitude, with the majority of these risks ca...
Source: Journal of the American Geriatrics Society - May 20, 2013 Category: Geriatrics Authors: Howard N. Hodis, Wendy J. Mack Tags: Updates on Aging Source Type: research

Stroke‐Associated Differences in Rates of Activity of Daily Living Loss Emerge Years Before Stroke Onset
ConclusionIn adults at risk of stroke, disproportionate ADL limitations emerge well before stroke onset. Excess disability in stroke survivors should not be entirely attributed to effects of acute stroke or quality of acute stroke care. Although there are many possible causal pathways between ADL and stroke, the association may be noncausal. For example, ADL limitations may be a consequence of stroke risk factors (e.g., diabetes mellitus) or early cerebrovascular ischemia.
Source: Journal of the American Geriatrics Society - May 13, 2013 Category: Geriatrics Authors: Benjamin D. Capistrant, Qianyi Wang, Sze Y. Liu, M. Maria Glymour Tags: Clinical Investigations Source Type: research

Optimal Blood Pressure for Cognitive Function: Findings from an Elderly African‐American Cohort Study
ConclusionHigh and low BP were associated with poorer cognitive performance. A joint optimal region of SBP and DBP for cognitive function has been identified, which may provide useful clinical information on optimal BP control in cognitive health and lead to better quality of life for elderly adults.
Source: Journal of the American Geriatrics Society - May 6, 2013 Category: Geriatrics Authors: Hai Liu, Sujuan Gao, Kathleen S. Hall, Frederick W. Unverzagt, Kathleen A. Lane, Christopher M. Callahan, Hugh C. Hendrie Tags: Clinical Investigations Source Type: research

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