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Source: Journal of the American Geriatrics Society

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Total 94 results found since Jan 2013.

Stroke‐Associated Differences in Rates of Activity of Daily Living Loss Emerge Years Before Stroke Onset
ConclusionIn adults at risk of stroke, disproportionate ADL limitations emerge well before stroke onset. Excess disability in stroke survivors should not be entirely attributed to effects of acute stroke or quality of acute stroke care. Although there are many possible causal pathways between ADL and stroke, the association may be noncausal. For example, ADL limitations may be a consequence of stroke risk factors (e.g., diabetes mellitus) or early cerebrovascular ischemia.
Source: Journal of the American Geriatrics Society - May 13, 2013 Category: Geriatrics Authors: Benjamin D. Capistrant, Qianyi Wang, Sze Y. Liu, M. Maria Glymour Tags: Clinical Investigations Source Type: research

Predicting Discharge to Institutional Long ‐Term Care After Stroke: A Systematic Review and Metaanalysis
ConclusionAge and stroke severity are important predictors of institutional long‐term care admission directly from the hospital after an acute stroke. Potentially modifiable factors should be the target of future research. Stroke outcome studies should report discharge destination, defining the model of care provided in the long‐term care setting.
Source: Journal of the American Geriatrics Society - September 1, 2017 Category: Geriatrics Authors: Jennifer K. Burton, Eilidh E.C. Ferguson, Amanda J. Barugh, Katherine E. Walesby, Alasdair M.J. MacLullich, Susan D. Shenkin, Terry J. Quinn Tags: Clinical Management of the Older Adult Source Type: research

Total and Differential White Blood Cell Counts in Late Life Predict 8‐Year Incident Stroke: The Honolulu Heart Program
ConclusionIn elderly Japanese‐American men, higher total WBC and neutrophil counts were independent predictors of overall stroke, as well as thromboembolic stroke.
Source: Journal of the American Geriatrics Society - March 4, 2015 Category: Geriatrics Authors: Ji Young Huh, George Webster Ross, Randi Chen, Robert D. Abbott, Christina Bell, Bradley Willcox, Lenore Launer, Helen Petrovitch, Brock Kaya, Kamal Masaki Tags: Clinical Investigations Source Type: research

Can Blood Pressure Be Lowered Safely in Older Adults with Lacunar Stroke? The Secondary Prevention of Small Subcortical Strokes Study Experience
ConclusionExcept for unsteadiness when standing, there was no difference according to age in individuals with lacunar stroke with respect to side effects potentially related to lowering blood pressure. Although the lower SBP target was not associated with lower likelihood of recurrent stroke, these exploratory analyses suggested a possible benefit related to vascular death.
Source: Journal of the American Geriatrics Society - April 6, 2015 Category: Geriatrics Authors: Carole L. White, Jeff M. Szychowski, Pablo E. Pergola, Thalia S. Field, Robert Talbert, Helena Lau, Kalyani Peri, Oscar R. Benavente, Tags: Clinical Investigations Source Type: research

Potential Value of Impaired Cognition in Stroke Prediction: A U.K. Population ‐Based Study
ConclusionCriteria for MCI, defined using MMSE scores or clinical criteria, can capture individuals at greater stroke risk. The results highlight the need to focus on stroke risk in individuals even with MCI.
Source: Journal of the American Geriatrics Society - April 3, 2017 Category: Geriatrics Authors: Blossom C. M. Stephan, Kathryn Richardson, George M. Savva, Fiona E. Matthews, Carol Brayne, Vladimir Hachinski Tags: Clinical Investigation Source Type: research

Influence of Hospital Type on Outcomes of Individuals Aged 80 and Older with Stroke Treated Using Intravenous Thrombolysis
ConclusionOlder adults with acute stroke treated with IVT had similar outcomes regardless of hospital characteristics.
Source: Journal of the American Geriatrics Society - June 2, 2017 Category: Geriatrics Authors: Francisco Purroy, Ana Vena, David C ánovas, Pere Cardona, Dolores Cocho, Elisa Cuadrado‐Godia, Angel Chamorro, Antonio Dávalos, Moisés Garcés, Meritxell Gomis, Jerzy Krupinski, Ernest Palomeras, Marc Ribó, Jaume Roquer, Marta Rubiera, Jordi Sanahuj Tags: Clinical Investigation Source Type: research

Men Lacking a Caregiver Have Greater Risk of Long ‐Term Nursing Home Placement After Stroke
ConclusionIn men aged 65 and older who have survived an ischemic stroke, the lack of an available caregiver is associated with triple the risk of NHP within 5 years.
Source: Journal of the American Geriatrics Society - October 26, 2017 Category: Geriatrics Authors: Justin Blackburn, Karen C. Albright, William E. Haley, Virginia J. Howard, David L. Roth, Monika M. Safford, Meredith L. Kilgore Tags: Clinical Investigation Source Type: research

High Level of Depressive Symptoms at Repeated Study Visits and Risk of Coronary Heart Disease and Stroke over 10 Years in Older Adults: The Three‐City Study
ConclusionElderly persons exposed to HLDS at several occasions over 10 years showed substantial increased risk of coronary heart disease and stroke events.
Source: Journal of the American Geriatrics Society - January 19, 2016 Category: Geriatrics Authors: Renaud Péquignot, Carole Dufouil, Christof Prugger, Karine Pérès, Sylvaine Artero, Christophe Tzourio, Jean‐Philippe Empana Tags: Clinical Investigations Source Type: research

Survival, Functional Status, and Eating Ability After Percutaneous Endoscopic Gastrostomy Tube Placement for Acute Stroke
ConclusionIn this community‐based sample, individuals who had had a stroke and a PEG tube placed had high mortality, and survivors were unlikely to be functional or mobile or to recover eating ability after hospitalization. A palliative care discussion including goals of care should occur before PEG tube placement is considered.
Source: Journal of the American Geriatrics Society - April 27, 2017 Category: Geriatrics Authors: Karl Meisel, Robert M. Arnold, Irena Stijacic Cenzer, John Boscardin, Alexander K. Smith Tags: Brief Report Source Type: research

Stroke Prevention in Atrial Fibrillation in Older Adults: Existing Knowledge Gaps and Areas for Innovation: A Summary of an American Federation for Aging Research Seminar
This article summarizes the meeting discussion and emphasizes innovative topic areas that may ultimately facilitate the application of novel preventive, diagnostic, and therapeutic insights into the management of older adults with AF. The opinions of those that participated in the meeting limit this report, which may not represent all of the questions that other experts in this field might raise.
Source: Journal of the American Geriatrics Society - September 19, 2013 Category: Geriatrics Authors: Steven A. Lubitz, Kenneth A. Bauer, Emelia J. Benjamin, Richard W. Besdine, Daniel E. Forman, Mahmut E. Gurol, Vivek Y. Reddy, Daniel E. Singer Tags: Special Articles Source Type: research

Use of Oral Anticoagulant Therapy in Older Adults with Atrial Fibrillation After Acute Ischemic Stroke
ConclusionDespite very high stroke risk, more than 40% of participants were not discharged with an OAC. Dominant reasons included fall risk, poor prognosis, older age, and dementia. These individuals’ high 1‐year mortality rate confirmed their high level of comorbidity. To improve anticoagulation decisions and outcomes in this population, future research should focus on strategies to mitigate fall risk, improve assessment of risks and benefits of anticoagulation in individuals with AF, and determine whether newer anticoagulants are safer in complex elderly and frail individuals.
Source: Journal of the American Geriatrics Society - December 29, 2016 Category: Geriatrics Authors: Emer R. McGrath, Alan S. Go, Yuchiao Chang, Leila H. Borowsky, Margaret C. Fang, Kristi Reynolds, Daniel E. Singer Tags: Clinical Investigation Source Type: research

Real ‐World Clinical Characteristics and Treatment Patterns of Individuals Aged 80 and Older with Nonvalvular Atrial Fibrillation: Results from the ReAl‐life Multicenter Survey Evaluating Stroke Study
ConclusionNearly one‐fifth of individuals with NVAF in this real‐world sample were aged 80 and older. Participants aged 80 and older were more likely to be female and have more comorbidities than those who were younger than 80. Those aged 80 and older with AF were less likely to receive anticoagulants than those who were younger than 80, but having more comorbidities and other individual‐level characteristics may explain this difference. When they were prescribed OACs, participants aged 80 and older had poorer quality of anticoagulation than those who were younger, suggesting opportunities for improvement.
Source: Journal of the American Geriatrics Society - April 10, 2017 Category: Geriatrics Authors: Murat Biteker, Özcan Başaran, Volkan Doğan, İbrahim Altun, Fatma Özpamuk Karadeniz, Ahmet İlker Tekkesin, Yasin Çakıllı, Ceyhan Türkkan, Mehmet Hamidi, Vahit Demir, Mustafa Ozan Gürsoy, Müjgan Tek Öztürk, Gökhan Aksan, Sabri Seyis, Mehmet B Tags: Clinical Investigation Source Type: research

Nondisease‐Specific Problems and All‐Cause Mortality in the REasons for Geographic and Racial Differences in Stroke Study
ConclusionNondisease‐specific problems were associated with mortality across a wide age spectrum. Future studies should explore whether treating these problems will improve survival and identify innovative healthcare models to address multiple nondisease‐specific problems simultaneously.
Source: Journal of the American Geriatrics Society - April 25, 2013 Category: Geriatrics Authors: C. Barrett Bowling, John N. Booth, Monika M. Safford, Heather E. Whitson, Christine S. Ritchie, Virginia G. Wadley, Mary Cushman, Virginia J. Howard, Richard M. Allman, Paul Muntner Tags: Clinical Investigations Source Type: research

Association Between Higher Plasma Lutein, Zeaxanthin, and Vitamin C Concentrations and Longer Telomere Length: Results of the Austrian Stroke Prevention Study
ConclusionThis study provides first evidence that higher lutein, zeaxanthin, and vitamin C concentrations in plasma are associated with longer LTL in normal elderly persons and suggest a protective role of these vitamins in telomere maintenance.
Source: Journal of the American Geriatrics Society - January 15, 2014 Category: Geriatrics Authors: Abhijit Sen, Gunther Marsche, Paul Freudenberger, Michael Schallert, Anna M. Toeglhofer, Christoph Nagl, Reinhold Schmidt, Lenore J. Launer, Helena Schmidt Tags: Clinical Investigations Source Type: research

Association Between Objectively Measured Physical Activity and Cognitive Function in Older Adults—The Reasons for Geographic and Racial Differences in Stroke Study
ConclusionHigher levels of objectively measured MVPA%, rather than LPA% or ST%, were associated with lower prevalence of cognitive impairment and better performance in memory and executive function in aging people. The amount of MVPA associated with lower prevalence of cognitive impairment is consistent with meeting PA guidelines.
Source: Journal of the American Geriatrics Society - December 22, 2015 Category: Geriatrics Authors: Wenfei Zhu, Virginia J. Howard, Virginia G. Wadley, Brent Hutto, Steven N. Blair, John E. Vena, Natalie Colabianchi, David Rhodes, Steven P. Hooker Tags: Clinical Investigations Source Type: research