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Post-reperfusion hyperperfusion after endovascular stroke treatment: a prospective comparative study of TCD versus MRI
Conclusions TCD is a reliable bedside tool to identify post-reperfusion hyperperfusion, correlates well with perfusion MRI, and indicates risk of reperfusion injury after MT.
Source: Journal of NeuroInterventional Surgery - September 15, 2023 Category: Neurosurgery Authors: Kneihsl, M., Hinteregger, N., Nistl, O., Deutschmann, H., Horner, S., Poltrum, B., Fandler-Höfler, S., Hatab, I., Haidegger, M., Pinter, D., Pichler, A., Willeit, K., Knoflach, M., Enzinger, C., Gattringer, T. Tags: Ischemic stroke Source Type: research

Augmentation of perfusion with simultaneous vasodilator and inotropic agents in experimental acute middle cerebral artery occlusion: a pilot study
Conclusion Results suggest that perfusion can be augmented in ischemic stroke with norepinephrine and hydralazine. Perfusion augmentation depends on degree of collateralization and territory in question, with some evidence of vascular steal.
Source: Journal of NeuroInterventional Surgery - August 29, 2023 Category: Neurosurgery Authors: Liu, M., Saadat, N., Jeong, Y. I., Roth, S., Niekrasz, M., Carroll, T., Christoforidis, G. A. Tags: Ischemic stroke Source Type: research

Contrast conservation measures during the global iohexol contrast shortage crisis did not affect stroke thrombectomy outcomes
Conclusions Modifying stroke workflow to adapt to the current global shortage in iohexol is feasible. Using diluted iohexol (50% contrast mixed with 50% heparinized saline) did not affect MT outcomes.
Source: Journal of NeuroInterventional Surgery - August 29, 2023 Category: Neurosurgery Authors: Almallouhi, E., Sattur, M., Lajthia, O., Kicielinski, K. P., Holmstedt, C., Lena, J. R., Al Kasab, S., Spiotta, A. M. Tags: Ischemic stroke Source Type: research

O09/90 Thrombectomy in ischemic stroke patients with large core but minor or absent ischemic changes on non-enhanced computed tomography
ConclusionIn patients with ASPECTS≥6, core volumes did not significantly modify the treatment effect of recanalization. Reperfusion and higher core volume were significantly associated with core overestimation which may explain the treatment effect of MT for patients with large ischemic core but minor ischemic changes on NECT.Abstract O09/90 Figure 1Abstract O09/90 Figure 2Disclosure of InterestNA.
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Broocks, G., Kniep, H., Bechstein, M., Paula Hanning, U. M., Kemmling, A., Fiehler, J., Meyer, L. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

O10/94 Ghost infarct core phenomenon after thrombectomy is associated with higher core lesion volume and degree of reperfusion
ConclusionOverestimation of the ischemic core occurred more often in patients presenting with large ICV and was associated with better functional outcomes. Although higher core volumes were associated with worse outcomes, timely vessel recanalization may result in significant treatment effects in this subgroup of patients. Large ICVs should not implicitly exclude patients from MT.Abstract O10/94 Figure 1Abstract O10/94 Figure 2Disclosure of InterestNA.
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Broocks, G., Meyer, L., Heit, J., Fiehler, J., Faizy, T. Tags: 2.2 ISCHEMIC - Imaging Source Type: research

O16/158 Artificial Intelligence based nationwide centralised decision supporting system for improving stroke case efficiency in Hungary
ConclusionUsing AI based centralized stroke imaging network fast and reliable decision support can be provided to a large nationwide stroke care system. The system was installed with the support of an EU grant EFOP 5.2.6.Disclosure of InterestIstvan Szikora has a consulting agreement with Brainomix Ltd.Zoltan Chadaide is a former employee of Brainomix Ltd.Edvard Benes is owner and CEO of eRAD-BBThe system was built by the support of an EU grant EFOP 5.2.6.The other authors have no relevant conflict of interest.
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Szikora, I., Magyar, B., Papai, G., Szudi, G., Kondor, M., Czencz, M., Nardai, S., Chadaide, Z., Benes, E., Ovary, C., Eross, L. Tags: 2.2 ISCHEMIC - Imaging Source Type: research

E-142 A new graphical interface to capture quantitative venous outflow metrics
ConclusionsOur newly developed graphical interface allows users to output quantitative metrics that may represent AIF and VOF. These metrics should be checked against existing scales for association and performance.Abstract E-142 Figure 1Disclosures G. Adusumilli: None. S. Christensen: 2; C; iSchemaView. 4; C; iSchemaView. T. Faizy: None. G. Albers: 2; C; iSchemaView, Genentech. 4; C; iSchemaView. M. Lansberg: None. J. Heit: 2; C; Medtronic, MicroVention. 6; C; iSchemaView.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Adusumilli, G., Christensen, S., Faizy, T., Albers, G., Lansberg, M., Heit, J. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

O-018 Utilizing DSC MR perfusion images for evaluation of hemorrhagic transformation after mechanical thrombectomy with Heidelberg grading and comparison to SWI, GRE, and CT
ConclusionAmong the 3 acquisitions, HT was identified more often on SWI/GRE than on CT or MR perfusion. For HT more likely to be clinically significant (Heidelberg grade 2 or higher), both SWI/GRE and DSC-MR perfusion performed similarly to CT. Thus, when obtaining DSC MR perfusion images for ischemic stroke imaging, SWI/GRE may not be necessary for evaluating HT.Abstract O-018 Figure 1Disclosures C. Reynolds: None. B. Renshaw: None. S. Vedantham: None. S. Rogers: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Reynolds, C., Renshaw, B., Vedantham, S., Rogers, S. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

O-026 Incremental value of arterial spin labeling (ASL) over conventional MRI sequences in the detection of intracranial arteriovenous malformations in patients with hereditary hemorrhagic telangiectasia (HHT)
ConclusionsOur findings underscore the incremental value of ASL in addition to conventional MRI sequences as a screening tool in the detection of brain AVMs in patients with HHT. ASL was more sensitive than conventional contrast-enhanced MRI alone, potentially improving diagnostic accuracy in this patient population with many small AVMs. These findings further highlight the need for further research to explore the benefits of integrating ASL sequences into the initial evaluation and routine follow-up of patients with sporadic and HHT-related brain AVMs.Abstract O-026 Figure 1Disclosures W. Han: None. A. Alyafaie: None. Y. ...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Han, W., Alyafaie, A., Li, Y., Hetts, S. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

O-027 Contrast density and volume on post-thrombectomy dual-energy head computed tomography predict delayed hemorrhagic transformation
ConclusionMaximum contrast density predicted the occurrence of delayed petechial hemorrhage, while contrast volume predicted the occurrence and volume of delayed parenchymal hematoma. The volume of contrast on DEHCT can serve as a useful predictor of DHT and may have implications for patient management.Abstract O-027 Figure 1Disclosures S. Ahn: None. S. Roth: None. Y. Ko: None. A. Bhamidipati: None. N. Mummareddy: None. R. Chitale: None. M. Fusco: None. M. Froehler: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Ahn, S., Roth, S., Ko, Y., Bhamidipati, A., Mummareddy, N., Chitale, R., Fusco, M., Froehler, M. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

E-223 Improved time to diagnosis with portable MR imaging
ConclusionPortable MRI is a promising innovation with the aim to expand patient access and improve diagnostic times so that critical and potential lifesaving imaging diagnoses can be promptly treated with the urgency that is required. While initial analysis provides evidence that portable MRI has advantages over conventional MRI systems including workflow efficiency and improved patient imaging times, this will need to be compared to the unfortunate negative drawbacks of lessened image resolution and limited imaging sequences that come with the convenience of portable MRI systems. If the hypothesis is further corroborated,...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Richardson, O., Richardson, A., Mukherjee, S. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

Tmax profile in computed tomography perfusion-based RAPID software maps influences outcome after mechanical thrombectomy in patients with basilar artery occlusion
Conclusions Perfusion deficit volume in Tmax >6 s on CTP-RAPID imaging maps and basilar artery on CTA score have potential as functional outcome predictors in patients with BAO after EVT.
Source: Journal of NeuroInterventional Surgery - June 16, 2023 Category: Neurosurgery Authors: Liu, X.-L., Hang, Y., Cao, Y., Jia, Z., Zhao, L. B., Shi, H.-B., Liu, S. Tags: Ischemic stroke Source Type: research

Association between time to treatment and clinical outcomes in endovascular thrombectomy beyond 6 hours without advanced imaging selection
Conclusion In this real-world study, there was minimal change in functional disability, sICH and in-hospital mortality within and across the late window. While confirmatory randomized trials are needed, these findings suggest that EVT remains feasible and safe when performed in AIS patients selected without advanced neuroimaging between 6–24 hours from stroke onset.
Source: Journal of NeuroInterventional Surgery - March 14, 2023 Category: Neurosurgery Authors: Dhillon, P. S., Butt, W., Podlasek, A., McConachie, N., Lenthall, R., Nair, S., Malik, L., Bhogal, P., Makalanda, H. L. D., Spooner, O., Krishnan, K., Sprigg, N., Mortimer, A., Booth, T. C., Lobotesis, K., White, P., James, M. A., Bath, P., Dineen, R. A., Tags: Ischemic stroke Source Type: research

Evaluation of time-resolved whole brain flat panel detector perfusion imaging using RAPID ANGIO in patients with acute stroke: comparison with CT perfusion imaging
Conclusions In our multicenter study, time-resolved whole brain FD-CTP was technically feasible, and qualitative and quantitative perfusion results correlated with those obtained with conventional CTP.
Source: Journal of NeuroInterventional Surgery - March 14, 2023 Category: Neurosurgery Authors: Kurmann, C. C., Kaesmacher, J., Cooke, D. L., Psychogios, M., Weber, J., Lopes, D. K., Albers, G. W., Mordasini, P. Tags: Open access, Neuroimaging Source Type: research

Endovascular thrombectomy beyond 24 hours from ischemic stroke onset: a propensity score matched cohort study
Conclusion In this real world study, EVT beyond 24 hours from stroke onset or last known well appeared to be feasible, with comparable safety and functional outcomes to EVT initiation between 6 and 24 hours. Randomized trials assessing the efficacy of EVT in the VL window are warranted, but may only be feasible with a large international collaborative approach.
Source: Journal of NeuroInterventional Surgery - February 14, 2023 Category: Neurosurgery Authors: Dhillon, P. S., Butt, W., Podlasek, A., Barrett, E., McConachie, N., Lenthall, R., Nair, S., Malik, L., James, M. A., Dineen, R. A., England, T. J. Tags: Ischemic stroke Source Type: research

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