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Source: BMJ Open
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Total 519 results found since Jan 2013.

Transcranial direct current stimulation combined with bodyweight support-tai chi footwork for motor function of stroke survivors: a study protocol of randomised controlled trial
This study will be an assessor-blinded randomised controlled trial involving 12-week intervention and 6-month follow-up. One hundred and thirty-five individuals with stroke will be randomly divided in a ratio of 1:1:1 into three groups. Control group A, control group B and intervention group C will receive tDCS and conventional rehabilitation programmes (CRPs), BWS-TC and CRP, tDCS-BWS-TC and CRP for 12 weeks, respectively. The primary outcome measures will include the efficacy (Fugl-Meyer Assessment), acceptability and safety of these interventions. The secondary outcome measures will include balance ability (ie, limits o...
Source: BMJ Open - March 7, 2023 Category: General Medicine Authors: Lai, M.-h., Xu, H.-c., Huang, M.-c., Lu, Y., Yang, K., Jiang, L.-m., Yu, X.-m. Tags: Open access, Rehabilitation medicine Source Type: research

Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) in adults with chronic stroke: protocol of a randomised controlled trial
This study will compare the effect of 50 hours of HABIT-ILE against usual motor activity and regular rehabilitation. HABIT-ILE will be provided in a 2-week, adult’s day-camp setting, promoting functional tasks and structured activities. These tasks will continuously progress by increasing their difficulty. Assessed at baseline, 3 weeks after and at 3 months, the primary outcome will be the adults-assisting-hand-assessment stroke; secondary outcomes include behavioural assessments for hand strength and dexterity, a motor learning robotic medical device for quality of bimanual motor control, walking endurance, question...
Source: BMJ Open - April 13, 2023 Category: General Medicine Authors: Ebner-Karestinos, D., Gathy, E., Carton de Tournai, A., Herman, E., Araneda, R., Dricot, L., Macq, B., Vandermeeren, Y., Bleyenheuft, Y. Tags: Open access, Rehabilitation medicine Source Type: research

Simulation modelling to study the impact of adding comprehensive stroke centres. Can we deliver endovascular thrombectomy sooner?
Conclusions This study suggests that adding one or two CSCs in the north of the Netherlands would have modest impact. Improving workflow efficiencies seems to be more potent when aiming to improve existing acute stroke care systems.
Source: BMJ Open - July 24, 2023 Category: General Medicine Authors: Maas, W. J., van der Zee, D.-J., Buskens, E., Uyttenboogaart, M., Lahr, M. M., CONTRAST investigators, Dippel, Majoie, Beusekom, Cate, Dammers, Dijkhuizen, Kappelle, Klijn, Koudstaal, Lingsma, Lugt, Maat, Nederkoorn, Oostenbrugge, Roos, Vivian, Zwam Tags: Open access, Neurology Source Type: research

Exoskeletal wearable robot on ambulatory function in patients with stroke: a protocol for an international, multicentre, randomised controlled study
This study is an international, multicentre, randomised controlled study at five institutions with a total of 150 patients with subacute stroke. Participants will be randomised into two groups (75 patients in the robot-assisted gait training (RAGT) group and 75 patients in the control group). The gait training will be performed with a total of 20 sessions (60 min/session); 5 sessions a week for 4 weeks. The RAGT group will receive 30 min of gait training using an exoskeleton (ANGEL LEGS M20, Angel Robotics) and 30 min of conventional gait training, while the control group will receive 60 min conventional gait training. In ...
Source: BMJ Open - August 11, 2023 Category: General Medicine Authors: Chang, W. H., Kim, T.-W., Kim, H. S., Hanapiah, F. A., Kim, D. H., Kim, D. Y. Tags: Open access, Rehabilitation medicine Source Type: research

Effectiveness of acceptance and commitment therapy in patients who had a stroke: a systematic review protocol
This study aimed to systematically evaluate the intervention effect of ACT in patients who had a stroke, which may provide further clinical evidence. Methods and analysis A systematic search of databases, including CNKI, WanFang Data, VIP, CBM, PubMed, Embase, Cochrane Library, CINAHL and APA PsycArticles, will be conducted from their inception to 31 October 2022. All randomised controlled trials, quasi-experiments and case studies relevant to ACT will be included in English and Chinese. Two independent reviewers will conduct the review, with data extraction and quality evaluation. Review Manager V.5.4 will be used to ass...
Source: BMJ Open - August 17, 2023 Category: General Medicine Authors: Xu, K., Zhang, X. Y., Ma, J. Y., Guo, X., Zhu, S.-S., Zhang, H., Sun, Y. Y. Tags: Open access, Mental health Source Type: research

Supportive care needs of patients who had a stroke: a scoping review protocol
Introduction Incidences of stroke are on the rise and approximately 80 million stroke survivors worldwide live with disabilities. Supportive care needs of stroke survivors are not adequately defined, and the assessment tools to help care service providers identify these needs are unclear. The overall aim of this scoping review will be to map the supportive care needs of stroke survivors against the Supportive Care Needs Framework. Methods and analysis This scoping review will be conducted following Arksey and O’Malley’s methodological framework and Joanna Briggs Institute (JBI) updated methodological guidance ...
Source: BMJ Open - August 24, 2023 Category: General Medicine Authors: Zhang, H., Xu, K., Ma, J. Y., Zhang, X. Y., Sun, Y. Y., Xiao, L. D., Yan, F., Luo, Y. Y., Tang, S. Tags: Open access, Health services research Source Type: research

A randomised controlled trial to compare the clinical and cost-effectiveness of prism glasses, visual search training and standard care in patients with hemianopia following stroke: a protocol
This study has been developed and supported by the UK Stroke Research Network Clinical Studies Group working with service users. Multicentre ethical approval was obtained through the North West 6 Research ethics committee (Reference 10/H1003/119). The trial is funded by the UK Stroke Association. Trial Registration: Current Controlled Trials ISRCTN05956042. Dissemination will consider usual scholarly options of conference presentation and journal publication in addition to patient and public dissemination with lay summaries and articles. Trial Registration Current Controlled Trials ISRCTN05956042.
Source: BMJ Open - July 17, 2014 Category: Journals (General) Authors: Rowe, F. J., Barton, P. G., Bedson, E., Breen, R., Conroy, E. J., Cwiklinski, E., Dodridge, C., Drummond, A., Garcia-Finana, M., Howard, C., Johnson, S., MacIntosh, C., Noonan, C. P., Pollock, A., Rockliffe, J., Sackley, C., Shipman, T., VISION (vision im Tags: Open access, Neurology, Ophthalmology, Rehabilitation medicine Protocol Source Type: research

Acupuncture for urinary incontinence after stroke: a protocol for systematic review
Introduction The aim of this study, which will include randomised controlled trials (RCTs), is to assess the efficacy and safety of acupuncture for patients with stroke and urinary incontinence. Methods and analysis RCTs will be searched electronically in the MEDLINE, EMBASE, Cochrane CENTRAL, CINAHL and four Chinese medical databases from their inception to present. Manual retrieval will also be conducted. RCTs will be included if acupuncture was evaluated as the sole or adjunct treatment for patients with stroke and urinary incontinence. The primary outcome will be measured by using the pad-weighing test. The secondary ...
Source: BMJ Open - February 23, 2016 Category: Journals (General) Authors: Sun, Z., Yu, N., Yue, J., Zhang, Q. Tags: Open access, Complementary medicine, Evidence based practice Protocol Source Type: research

Service factors causing delay in specialist assessment for TIA and minor stroke: a qualitative study of GP and patient perspectives
Conclusions Primary and emergency care providers need to review how they can best handle patients presenting with symptoms that could be due to stroke or TIA. In general practice, this may include receptionist training and/or triage by a nurse or doctor. Mechanisms need to be established to enable direct referral to the TIA clinic when patients whose symptoms have resolved present to other agencies. Further work is needed to improve diagnostic accuracy by non-specialists.
Source: BMJ Open - May 16, 2016 Category: Journals (General) Authors: Wilson, A., Coleby, D., Regen, E., Phelps, K., Windridge, K., Willars, J., Robinson, T. Tags: Open access, Cardiovascular medicine, Emergency medicine, Health services research, Qualitative research Source Type: research

Community-based Rehabilitation Training after stroke: protocol of a pilot randomised controlled trial (ReTrain)
Introduction The Rehabilitation Training (ReTrain) intervention aims to improve functional mobility, adherence to poststroke exercise guidelines and quality of life for people after stroke. A definitive randomised controlled trial (RCT) is required to assess the clinical and cost-effectiveness of ReTrain, which is based on Action for Rehabilitation from Neurological Injury (ARNI). The purpose of this pilot study is to assess the feasibility of such a definitive trial and inform its design. Methods and analysis A 2-group, assessor-blinded, randomised controlled external pilot trial with parallel mixed-methods process evalu...
Source: BMJ Open - October 2, 2016 Category: Journals (General) Authors: Dean, S. G., Poltawski, L., Forster, A., Taylor, R. S., Spencer, A., James, M., Allison, R., Stevens, S., Norris, M., Shepherd, A. I., Calitri, R. Tags: Open access, Health services research, Rehabilitation medicine, Sports and exercise medicine Protocol Source Type: research

Early real-world evidence of persistence on oral anticoagulants for stroke prevention in non-valvular atrial fibrillation: a cohort study in UK primary care
Conclusions Observed differential prescribing of OACs can result in channelling bias in comparative effectiveness research. Persistence patterns changed over follow-up time, but there are indications of improved persistence rates with apixaban over other OACs in the UK. A larger study with longer follow-up is needed to corroborate findings. This study is registered on ClinicalTrials.gov (NCT02488421).
Source: BMJ Open - September 25, 2016 Category: Journals (General) Authors: Johnson, M. E., Lefevre, C., Collings, S.-L., Evans, D., Kloss, S., Ridha, E., Maguire, A. Tags: Open access, Cardiovascular medicine, Epidemiology, General practice / Family practice Research Source Type: research

Measurement properties of self-report physical activity assessment tools in stroke: a protocol for a systematic review
Discussion This systematic review will provide an extensive review of the measurement properties and clinical utility of self-report physical activity assessment tools used in individuals with stroke, which would benefit clinicians and researchers. Trial registration number PROSPERO CRD42016037146.
Source: BMJ Open - February 12, 2017 Category: Journals (General) Authors: Martins, J. C., Aguiar, L. T., Nadeau, S., Scianni, A. A., Teixeira-Salmela, L. F., Faria, C. D. C. d. M. Tags: Open access, Neurology, Rehabilitation medicine Protocol Source Type: research

154: a pharmacoeconomic evaluation to make decision: is the use of simvastatin 10 mg as an otc medication cost-effective for the primary prevention of stroke amongst women in iran?
Conclusion: In Iran no threshold has been determined but the results were compared with the threshold that WHO recommended (GDP per capita for Iran is $5442.9 for 2014 by World Bank). Considering this threshold, the evaluated intervention could be considered cost-effective.
Source: BMJ Open - February 7, 2017 Category: Journals (General) Authors: Amirsadri, M., Dorri, N. Tags: Open access Oral Source Type: research

1 The use and impact of 12-lead electrocardiograms in acute stroke patients: a systematic review
Conclusion Future studies should be based in the prehospital environment and should investigate whether undertaking an electrocardiogram in the prehospital setting affects clinical management decisions or has an association with mortality or morbidity. Conflict of interest None declared Funding This work was supported by School of Health Sciences PhD bursary – University of Surrey, and South East Coast Ambulance Service NHS Foundation Trust.
Source: BMJ Open - May 21, 2017 Category: General Medicine Authors: Munro, S., Quinn, T., Cooke, D., Joy, M. Source Type: research

Solution Focused Brief Therapy in Post-Stroke Aphasia (SOFIA): feasibility and acceptability results of a feasibility randomised wait-list controlled trial
Conclusion The high retention and adherence rates, alongside the qualitative data, suggest the study design was feasible and therapy approach acceptable even to people with severe aphasia. These results indicate a definitive randomised controlled trial of the intervention would be feasible. Trial registration number NCT03245060.
Source: BMJ Open - August 18, 2021 Category: General Medicine Authors: Northcott, S., Thomas, S., James, K., Simpson, A., Hirani, S., Barnard, R., Hilari, K. Tags: Open access, Rehabilitation medicine Source Type: research