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Trends and Predictors of Utilization of Endovascular Coiling vs Microsurgical Clipping of Ruptured Intracranial Aneurysms (P2.292)
Conclusions:Study highlights significant increase in utilization rates of coiling over the past eleven years for RIA in USA.Disclosure: Dr. Balasetti has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Jani has nothing to disclose. Dr. To has nothing to disclose. Dr. Fessler has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Balasetti, V., Patel, U., Jani, V., To, C. Y., Fessler, R. Tags: Subarachnoid Hemorrhage, Intracranial Aneurysm, and Other Cerebrovascular Malformations Source Type: research

Endovascular treatment of pediatric intracranial aneurysms: A systematic review and meta-analysis (P2.295)
Conclusions:In general, pediatric patients who undergo endovascular treatment for intracranial aneurysms have a favorable prognosis and excellent survival. There are no differences between coiling, stent-assisted coiling, and flow diversion with respect to periprocedural complications and long-term outcomes.Disclosure: Dr. Bond has nothing to disclose. Dr. Bond has nothing to disclose. Dr. Ilorah has nothing to disclose. Dr. Kattah has received personal compensation for activities with Pfizer as a consultant. Dr. Kattah has received personal compensation in an editorial capacity as an editor for E-Medicine.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Bond, B., Bond, K., Ilorah, C., Kattah, J. Tags: Subarachnoid Hemorrhage, Intracranial Aneurysm, and Other Cerebrovascular Malformations Source Type: research

Hospital utilization, length stay and inhospital mortality in patients with subarachnoid hemorrhage among different racial groups (P2.300)
Conclusions:There are significant differences in hospital utilization, in hospital mortality, LOS and disposition among different racial groups. Interestingly minorities have higher utilization and lower inhospital mortality compared to Whites. Further studies needs to be warranted.Disclosure: Dr. Maud has nothing to disclose. Dr. Qureshi has nothing to disclose. Dr. Afzal has nothing to disclose. Dr. Qureshi has nothing to disclose. Dr. Piriyawat has nothing to disclose. Dr. Khatri has nothing to disclose. Dr. Rodriguez has nothing to disclose. Dr. Cruz-Flores has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Maud, A., Qureshi, M., Afzal, M.-R., Qureshi, I., Piriyawat, P., Khatri, R., Rodriguez, G., Cruz-Flores, S. Tags: Subarachnoid Hemorrhage, Intracranial Aneurysm, and Other Cerebrovascular Malformations Source Type: research

Diffusion Tensor Imaging of Corticospinal Tract Recovery after Intra-arterial Mesenchymal Stem Cell Infusion in a Canine Stroke Model (P1.266)
Conclusions:Serial DTI-DTT imaging after IA MSCs therapy in large animal stroke model appears to have a trend towards higher change in FA. These findings could support further development of DTI-DTT biomarkers to measure neurologic recovery in experimental models as well as early clinical trials of novel stroke therapies.Disclosure: Dr. Guada has nothing to disclose. Dr. Pattany has nothing to disclose. Dr. Ramdas has nothing to disclose. Dr. Atchaneeyasakul has nothing to disclose. Dr. Saigal has nothing to disclose. Dr. Yavagal has received personal compensation for activities with Medtronic and Guidepoint as a consultant.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Guada, L., Pattany, P., Ramdas, K., Atchaneeyasakul, K., Saigal, G., Yavagal, D. Tags: Genetic Stroke Syndromes, Biomarkers, and Translational/Basic Research Source Type: research

Development and Feasibility of a Canine Endovascular Reversible Middle Cerebral Artery Occlusion Stroke Model: a Novel anterior circulation approach (P1.267)
Conclusions:Here we report the successful development of an endovascular reversible MCAo model in the canine by an anterior circulation approach. A learning curve is seen in the successful implementation of this model, as shown by our results.Disclosure: Dr. Guada has nothing to disclose. Dr. Ramdas has nothing to disclose. Dr. Atchaneeyasakul has nothing to disclose. Dr. Watanabe has nothing to disclose. Dr. Sidani has nothing to disclose. Dr. Yavagal has received personal compensation for activities with Medtronic and Guidepoint as a consultant.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Guada, L., Ramdas, K., Atchaneeyasakul, K., Watanabe, M., Sidani, C., Yavagal, D. Tags: Genetic Stroke Syndromes, Biomarkers, and Translational/Basic Research Source Type: research

Stable incidence but declining case-fatality rates of subarachnoid hemorrhage in a population
Conclusions: Although the incidence of SAH remained stable in this population-based region, 5-day, 30-day, and 90-day case-fatality rates declined significantly. Advances in surgical and medical management, along with systems-based changes such as the emergence of neurocritical care units, are potential explanations for the reduced case-fatality.
Source: Neurology - November 20, 2016 Category: Neurology Authors: Mackey, J., Khoury, J. C., Alwell, K., Moomaw, C. J., Kissela, B. M., Flaherty, M. L., Adeoye, O., Woo, D., Ferioli, S., De Los Rios La Rosa, F., Martini, S., Khatri, P., Broderick, J. P., Zuccarello, M., Kleindorfer, D. Tags: Outcome research, Subarachnoid hemorrhage ARTICLE Source Type: research

Subarachnoid Hemorrhage with and without Concomitant Sickle Cell Disease, a Comparison Using the Nationwide Inpatient Sample (S4.004)
Conclusions: Based on these data, 2 out of every 1000 cases of SAH in the United States, will be related to SCD. SAH occurs at a much younger age in patients with SCD. Prognosis in patients with SAH related to SCD may be better than in non-SCD patients.Disclosure: Dr. Al Zahmi has nothing to disclose. Dr. Conners has nothing to disclose. Dr. Cutting has nothing to disclose. Dr. Cherian has nothing to disclose. Dr. Song has nothing to disclose. Dr. Lee has nothing to disclose. Dr. Garg has received research support from AHA and RTSC. Dr. Ouyang has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Al Zahmi, F., Conners, J., Cutting, S., Cherian, L., Song, S., Lee, V., Garg, R., Ouyang, B. Tags: Health Disparities and Sex Differences in Stroke Source Type: research

Intra-Arterial Mesenchymal Stem Cells in a Large Animal Endovascular Canine Stroke Model: Findings on Serial Diffusion Tensor Imaging (S42.007)
Conclusions: Serial DTI-DTT imaging after IA cell therapy shows improvement in white matter tracts correlating with neurologic recovery. This supports further development of DTI-DTT biomarkers to measure neurologic recovery in experimental models as well as early clinical trials.Disclosure: Dr. Guada has nothing to disclose. Dr. Pattany has nothing to disclose. Dr. Ramdas has nothing to disclose. Dr. Yavagal has received personal compensation for activities with Covidien/evV3 as a consultant and Steering Committee Member.
Source: Neurology - February 7, 2016 Category: Neurology Authors: Guada, L., Pattany, P., Ramdas, K., Yavagal, D. Tags: Stroke Mechanism and Modifiers Source Type: research

Watch your neighbor's garden, or Delphi's oracle for unruptured intracranial aneurysm treatment
Current management recommendations for patients with unruptured intracranial aneurysms (UIAs) include surgical clipping, endovascular coiling, or noninterventional follow-up.1 Several population-based studies and meta-analyses identified risk factors associated with aneurysm growth and rupture,2 some of which are modifiable (arterial hypertension, smoking, and excessive alcohol consumption) and some of which are not (increasing age, female sex, ethnic origin, aneurysm size, and morphology); however, no randomized controlled data exist on the potential benefit of preventive intervention for UIAs. The multinational TEAM (Tri...
Source: Neurology - September 7, 2015 Category: Neurology Authors: Bijlenga, P., Stapf, C. Tags: All Cerebrovascular disease/Stroke EDITORIALS Source Type: research