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Relationship between carotid arterial properties and cerebral white matter hyperintensities
Conclusions: Large carotid artery diameters are associated with greater burden of white matter hyperintensity (WMH) in this multiethnic population. The association between increased diameters, decreased STRAIN, and greater WMH burden is more pronounced among Hispanics. These associations suggest a potential important pathophysiologic role of extracranial large artery remodeling in the burden of WMH.
Source: Neurology - May 22, 2017 Category: Neurology Authors: Rundek, T., Della-Morte, D., Gardener, H., Dong, C., Markert, M. S., Gutierrez, J., Roberts, E., Elkind, M. S. V., DeCarli, C., Sacco, R. L., Wright, C. B. Tags: fMRI, Other cerebrovascular disease/ Stroke, Assessment of cognitive disorders/dementia ARTICLE Source Type: research

Ultrasound Criteria for Assessment of Vertebral Artery Origins (P4.251)
Conclusions:Ultrasound has good sensitivity and excellent specificity for detecting vertebral origin occlusion. Flow velocity can be used to screen for severe stenosis of vertebral artery at origin.Disclosure: Dr. Rice has nothing to disclose. Dr. Strohm has nothing to disclose. Dr. Raber has nothing to disclose. Dr. Katzan has received personal compensation for activities with Pfizer, Genentech, Inc, and Cardionet, Inc Dr. Uchino has nothing to disclose. Dr. Hussain has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Rice, C., Strohm, T., Raber, L., Katzan, I., Uchino, K., Hussain, M. Tags: Acute and Diagnostic Imaging in Ischemic Stroke and TIA Source Type: research

Recent Nationwide Trends in Transcranial Doppler Utilization During Acute Ischemic Stroke Hospitalizations (P4.296)
Conclusions:Over the last decade there has been a slight but steady decrease in the use of TCD during AIS hospitalizations in the US. Future studies should examine the cost-utility of TCD, especially with the advent of endovascular stroke treatment systems.Disclosure: Dr. Liu has nothing to disclose. Dr. Lunagariya has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Feng has nothing to disclose. Dr. Ovbiagele has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Liu, Y., Lunagariya, A., Patel, U., Patel, A., Feng, W., Ovbiagele, B. Tags: In-Hospital Stroke Care Source Type: research

The relationship between chemerin levels and carotid intima-media thickness in patients with ischemic stroke (P1.262)
Conclusions:Consequently, this study showed that serum chemerin levels may play role in atherosclerosis and ischemic stroke.Study Supported by: Fırat University (FÜBAP)Disclosure: Dr. Demir has nothing to disclose. Dr. Atas has nothing to disclose. Dr. Aytaç has nothing to disclose. Dr. Gonen has nothing to disclose. Dr. Erten has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Demir, C., Ataş, I., Aytac, E., Gonen, M., Erten, Z. Tags: Genetic Stroke Syndromes, Biomarkers, and Translational/Basic Research Source Type: research

Is there a correlation between embolic strokes of undetermined source (ESUS) and patent foramen ovale (PFO)? - A contrasted Transcranial Doppler Ultrasound (cTCD) study. (P6.287)
Conclusions:Massive shunt (the so-called "curtain pattern") during Valsalva maneuver at cTCD was predictive of ESUS in patients with stroke and PFO. The presence of RLS at rest was not statiscally relevant, probably because of the small sample size.Disclosure: Dr. Scavasine has nothing to disclose. Dr. Chamma has nothing to disclose. Dr. Bruch has nothing to disclose. Dr. Braga has nothing to disclose. Dr. Bazan has nothing to disclose. Dr. Massaro has nothing to disclose. Dr. Germiniani has nothing to disclose. Dr. Lange has nothing to disclose. Dr. Zetola has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Scavasine, V., Chamma, J., Bruch, T., Braga, G., Bazan, R., Massaro, A., Germiniani, F., Lange, M., Zetola, V. Tags: Prevention of Cerebrovascular Disease Source Type: research

Outcome and Prognosis of Middle Cerebral Artery Occlusive Disease in a Sample of Egyptian Patients. (P3.255)
Conclusions:Symptomatic MCA stenosis is associated with higher risk of recurrent cerebral stroke.Disclosure: Dr. Elsaid has nothing to disclose. Dr. El-Mitwalli has nothing to disclose. Dr. Farrag has nothing to disclose. Dr. Abdel Salam has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Elsaid, N., El-Mitwalli, A., Farrag, M., Abdel Salam, M. Tags: Cerebrovascular Disease Epidemiology Source Type: research

Patterns of utilization of extracranial neurovascular ultrasound in patients with syncope in the context of the American Academy of Neurology (AAN) Choosing Wisely initiative. (P2.187)
Conclusions:The clinical value of ENVU in syncope evaluation is not well established. Our study demonstrated a local increase utilization of ENVU despite AAN recommendations. We suspect our observations are not unique to our institution, and encourage colleagues to review the Choosing Wisely campaign in order to implement cost – effective practices in the evaluation of syncope.Study Supported by: n/aDisclosure: Dr. Ortiz-Garcia has nothing to disclose. Dr. Bruzzone Giraldez has nothing to disclose. Dr. Andino has nothing to disclose. Dr. Sweis has nothing to disclose. Dr. Gomez has received personal compensation for ...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ortiz-Garcia, J., Bruzzone, M., Andino, D., Sweis, R., Gomez, C., Biller, J. Tags: General Neurology: Practice Improvement and Novel Approaches to Care Source Type: research

Reducing Resource Utilization and Improving Efficiency Using A Separate Activation for Emergent Large Vessel Occlusion Ischemic Strokes (P5.264)
Conclusions:Partitioning of the acute stroke management process with a separate activation for probable large vessel occlusions resulted in a reduction of vascular imaging utilization and did not result in slower door-to-groin times.Study Supported by: No funding.Disclosure: Dr. Tan has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Shaykhinurov has nothing to disclose. Dr. Rodrigazo has nothing to disclose. Dr. Neiswander has nothing to disclose. Dr. Majidi has nothing to disclose. Dr. Burger has nothing to disclose. Dr. Leon Guerrero has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Tan, M., Patel, S., Shaykhinurov, E., Rodrigazo, M. C., Neiswander, B., Majidi, S., Burger, K., Guerrero, C. L. Tags: Acute Cerebrovascular Interventional Therapies Source Type: research

More to Atherosclerosis than Stenosis: Symptomatic Carotid Artery with Intraplaque Hemorrhage (P5.285)
Conclusions:Current guidelines only address the degree of arterial narrowing when recommending carotid revascularization procedures for secondary stroke prevention. The most recent AHA-ASA guideline advises against revascularization procedures in less than 50% CA stenosis. These guidelines do not account for plaque morphology that may predict a high risk of early stroke recurrence as demonstrated by our patient.Disclosure: Dr. Rai has nothing to disclose. Dr. Thaler has received personal compensation for activities with St. Jude Medical WL and Gore Associates as a consultant. Dr. Leung has nothing to disclose. Dr. Madan ha...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Rai, S., Thaler, D., Leung, L., Madan, N., Salehi, P. Tags: SubAcute Interventional Therapies in Cerebrovascular Disease Source Type: research

Achieving LDL
Conclusions: Achieved LDL<70 vs. 70-120 mg/dL in ischemic stroke patients was associated with a pattern of reduced atherosclerotic plaque progression at one year, but this difference did not reach statistical significance. Future larger studies are warranted.Disclosure: Dr. Zhang has nothing to disclose. Dr. Liu has nothing to disclose. Dr. Hua has nothing to disclose. Dr. Song has nothing to disclose. Dr. Ji has nothing to disclose. Dr. Ren has nothing to disclose. Dr. Song has nothing to disclose. Dr. Liu has nothing to disclose. Dr. Feng has nothing to disclose. Dr. Ovbiagele has nothing to disclose. Dr. Ding has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Zhang, Q., Liu, S., Hua, Y., Song, H., Ji, X., Ren, Y., Song, Y., Liu, R., Feng, W., Ovbiagele, B., Ding, J. Tags: Carotid Disease Source Type: research

Frequency of Microemboli in Symptomatic Carotid Stenosis Compared to Carotid Occlusion (P1.234)
Conclusions: Microemboli are relatively common in both symptomatic carotid occlusions and stenosis; embolization may play a significant role in recurrent ischemia in both groups.Disclosure: Dr. Zandieh has nothing to disclose. Dr. Liberman has nothing to disclose. Dr. Loomis has nothing to disclose. Dr. Raser-Schramm has nothing to disclose. Dr. Wilson has nothing to disclose. Dr. Torres has nothing to disclose. Dr. Ishida has nothing to disclose. Dr. Gallatti has nothing to disclose. Dr. Gallatti has nothing to disclose. Dr. Yates has nothing to disclose. Dr. Davis has nothing to disclose. Dr. Cucchiara has received perso...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Zandieh, A., Liberman, A., Loomis, C., Raser-Schramm, J., Wilson, C., Torres, J., Ishida, K., Pawar, S., Gallatti, N., Yates, M., Davis, R., Cucchiara, B. Tags: Carotid Disease Source Type: research

LDL and Systolic Blood Pressure Are Associated with Coated-Platelet Levels in Patients with Asymptomatic Carotid Atherosclerosis (P1.235)
Conclusions: In asymptomatic patients with carotid atherosclerosis, higher LDL and lower SBP were associated with increased coated-platelet levels. The relationship between LDL and coated-platelet levels is consistent with the recognized role of hypercholesterolemia in cardiovascular disease. The significance of the association between lower SBP and higher coated-platelet levels is less clear. These findings should be confirmed in prospective studies. Supported by grants from the American Heart Association and Clinical Science Research & Development Service (CX000340).Disclosure: Dr. Kirkpatrick has nothing to disclose...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Kirkpatrick, A., Nguyen, N., Vincent, A., Guthery, L., Mathews, E., Malatinszky, G., Donna-Ferreira, F., Dale, G., Prodan, C. Tags: Carotid Disease Source Type: research

Degree of Stenosis by Angiography Does Not Influence Risk of Endarterectomy or Stenting in Patients with Severe Asymptomatic Carotid Stenosis (P1.236)
Conclusions:This is the largest contemporary study of carotid angiograms performed in 662 patients with severe asymptomatic carotid stenosis. No relationship was detected between severity of stenosis and 30-day stroke and death. The safety of CEA and CAS in asymptomatic patients limits detection of other factors that may increase risk because so few events complicate these procedures.Disclosure: Dr. Brott has received personal compensation for activities with 3D Communications and Edwards Lifesciences as a consultant. Dr. Lal has nothing to disclose. Dr. Voeks has nothing to disclose. Dr. Heck has received personal compens...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Brott, T., Lal, B., Voeks, J., Heck, D., Brooks, W., Bozorgchami, H., Roubin, G. Tags: Carotid Disease Source Type: research

Etiologic Epidemiology of Ischemic Stroke (A Study About 2450 Cases) (P1.120)
Conclusions: The main etiology of ischemic stroke in elderly person was lacunar infract followed by atherosclerosis and atrial fibrillation. In Young adults, etiology differs according to country. In our study Carotid dissection takes the first place in patients with age under 45 years old Etiological investigations and a swift implementation of strategy for the prevention of the risk factors are important faced with increased incidence of ischemic stroke. Despite a complete assessment, ischemic stroke etiology can remain indeterminate.Disclosure: Dr. bouzidi has nothing to disclose. Dr. AYADI has nothing to disclose. Dr. ...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Bouzidi, N., Ayadi, B., Bouchhima, I., Turki, E., Damak, M., Mhiri, C. Tags: Cerebrovascular Disease: Epidemiology Source Type: research

Median Nerve Ultrasound During the Acute Stroke Period: A New Method of Early Detection (P3.299)
Conclusions: The results suggest that physical exam and BCTQ are not useful for detecting CTS in the setting of ischemic stroke. Median nerve US may be a helpful diagnostic adjunct in early identification and intervention for CTS.Disclosure: Dr. Lin has nothing to disclose. Dr. Loochtan has nothing to disclose. Dr. Hobson-Webb has received personal compensation for activities with Genzyme and Sanofi for speaking. Dr. Hobson-Webb holds stock and/or stock options in Aerpio Therapeutics. Dr. Hobson-Webb has received research support from Valerion Therapuetics and C
Source: Neurology - April 3, 2016 Category: Neurology Authors: Lin, C., Loochtan, A., Hobson-Webb, L. Tags: Neurorehabilitation Source Type: research

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