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Specialty: Neurology
Source: Neurology
Education: Study

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Total 1979 results found since Jan 2013.

Delays in Door-to-Needle Time for Acute Ischemic Stroke in the Emergency Department: A Comprehensive Stroke Center Experience (P4.273)
Conclusions:Important and common causes of delay in IVT for AIS were identified in a review of charts at our comprehensive stroke center. The authors recommend strategies to achieve faster DTN time for each of the delaying factor categories including faster acquisition and interpretation of stroke imaging, more effective triage protocols, and faster blood pressure control for AIS patients who are eligible for IVT.Disclosure: Dr. Mowla has nothing to disclose. Dr. Doyle has nothing to disclose. Dr. Lail has nothing to disclose. Dr. Deline has nothing to disclose. Dr. Ching has nothing to disclose. Dr. Crumlish has nothing t...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Mowla, A., Doyle, J., Lail, N., Deline, C., Ching, M., Crumlish, A., Sawyer, R. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Intravenous thrombolytic treatment of acute ischemic stroke in patients older and younger than 80 years: experience from one hospital (p4.275)
Conclusions:We found that IV thrombolysis still has benefit in people older than 80 years old but treatment decision should be taken with caution in well selected cases.Study Supported by: Not applicableDisclosure: Dr. Bayona has nothing to disclose. Dr. Diaz-Cruz has received research support from EMD Serono and Verily. Dr. Valencia-Mendoza has nothing to disclose. Dr. Díaz has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Bayona, H., Diaz-Cruz, C., Valencia-Mendoza, C., Diaz, A. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Risk of Symptomatic Intracranial Hemorrhage and Clinical Outcome after Intravenous Thrombolysis in Posterior Circulation Stroke: Results from the SITS-EAST Registry (P4.276)
Conclusions:In patients treated with IVT, data from SITS-EAST registry showed that localization of stroke in the posterior circulation was associated with better 90-day clinical outcome than in the anterior circulation. Nevertheless, the risk of SICH was only statistically insignificantly lower in PCS versus ACS patients.Disclosure: Dr. Herzig received personal compensation from Boehringer Ingelheim for serving on a scientific advisory board. Dr. Waishaupt has nothing to disclose. Dr. Belaskova has nothing to disclose. Dr. Vitkova has nothing to disclose. Dr. Blejcharova has nothing to disclose. Dr. Geier has nothing to di...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Herzig, R., Waishaupt, J., Belaskova, S., Vitkova, E., Blejcharova, K., Geier, P., Tomek, A., Bar, M., Vaclavik, D., Mikulik, R., Valis, M. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Intravenous Tissue Plasminogen Activator for Patients with Mild or Rapidly Improving Ischemic Strokes and Large Vessel Occlusions: Examining In-hospital Outcomes (P4.277)
Conclusions:Our study suggests that tPA in mild LVO patients does not introduce additional risk in terms of sICH, in-hospital mortality, change in NIHSS, or discharge mRS. Future investigations should examine 90-day mRS scores in order to better understand long-term functional outcomes after treatment.Disclosure: Dr. Wagner has received personal compensation for activities with Genentech as a speaker. Dr. McGraw has nothing to disclose. Dr. McCarthy has nothing to disclose. Dr. Bartt has nothing to disclose. Dr. Jensen has nothing to disclose. Dr. Orlando has nothing to disclose. Dr. Bar-Or has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Wagner, J., McGraw, C., McCarthy, K., Bartt, R., Jensen, J., Orlando, A., Bar-Or, D. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Time Trend Analysis of Intravenous Thrombolytic Delivery across the Academic Year: an Academic Tertiary Medical Center Experience (P4.278)
Conclusions:Although not statistically significant, there is a decrease in DTN time (4.38 minutes) from the first academic quarter to the last quarter. Over the course of academic year, residents become more efficient in managing AIS, but ample attending supervision is the key to resident confidence and best patient care.Disclosure: Dr. Mehla has nothing to disclose. Dr. Shah has nothing to disclose. Dr. Lail has nothing to disclose. Dr. Vaughn has nothing to disclose. Dr. Joshi has nothing to disclose. Dr. Deline has nothing to disclose. Dr. Sawyer has nothing to disclose. Dr. Ching has nothing to disclose. Dr. Mowla has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Mehla, S., Shah, H., Lail, N., Vaughn, C., Joshi, S., Deline, C., Sawyer, R., Ching, M., Mowla, A. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Analysis of Diagnostic Accuracy, Workflow and Time to Treatment during In-house 'Stroke Codes (P4.282)
Conclusions:Only a minority of ‘stroke codes’ were activated for new ischemic stroke/TIA or large vessel occlusion, while the remaining codes were for altered mental status, seizure, or non-neurologic etiologies. A notable delay occurred between time of code call and imaging. Improved identification of focal symptoms and use of parallel processing for evaluation will be studied in a prospective analysis in effort to improve patient identification and response times.Disclosure: Dr. Manners has nothing to disclose. Dr. Jadhav has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Manners, J., Jadhav, A. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Rapidly improving neurological deficit of stroke; case series in Academic institute, KAUH, Jeddah (P4.283)
Conclusions:Rapidly improving patient represent a challenge to whether tPA should be given. However, the good outcome with thrombolytic therapy observed in our study, will hopfuly support the decision to treat.Study Supported by: nonDisclosure: Dr. khoja has nothing to disclose. Dr. Alshaer has nothing to disclose. Dr. al-Turkistani has nothing to disclose. Dr. Al-Mekhalfi has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: khoja, a., Al-Shaer, D., al-Turkistani, a., Al-Mekhalfi, M. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Barriers to thrombolysis in a tertiary care institute in eastern India (P4.284)
Conclusions:Thus this study highlights the various lacunaes we have for thrombolysis and gives us scope to further improve and increase its rate.Disclosure: Dr. Chatterjee has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Chatterjee, A. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Resident door to needle Analysis: A retrospective Chart rEview (RACE) (P4.285)
Conclusions:Recognition and token awards for neurology residents can lead to shorter DTN times which could, in turn, improve outcomes in AIS. However, this approach requires a continued review of diagnostic accuracy and adverse events to ensure quality of care is not compromised for the sake of speed.Disclosure: Dr. Patel has nothing to disclose. Dr. Mehta has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Patel, N., Mehta, S. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

High values of baseline and 24-hour Mean Arterial Pressure are associated with lower chance of early neurological improvement in acute stroke patients treated with thrombolysis (P4.286)
Conclusions:High baseline and 24-hr MAP values are associated with lower chance of achieving ENI after IV thrombolysis. Further studies are needed to better understand whether acute BP dysregulation can influence different clinical courses in the early phase of IV thrombolysis.Disclosure: Dr. Lorenzano has nothing to disclose. Dr. Caselli has nothing to disclose. Dr. Zingaro has nothing to disclose. Dr. Orlando has nothing to disclose. Dr. Toni has received research support from Bayer, Medtronic, and Boehriger Ingelheim.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Lorenzano, S., Caselli, M. C., Zingaro, A., Orlando, F., Toni, D. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Can admission Brain Natriuretic Peptide level predict outcome after intravenous thrombolysis in acute ischemic stroke? (P4.287)
Conclusions:Elevated BNP level was not found to be an independent marker of poor outcome in acute ischemic stroke patients following intravenous thrombolysis.Disclosure: Dr. Gupta has nothing to disclose. Dr. Finlay has nothing to disclose. Dr. Jacob has nothing to disclose. Dr. Raina has nothing to disclose. Dr. Lee has nothing to disclose. Dr. Hinduja has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Gupta, H., Finlay, C., Jacob, S., Raina, S., Lee, R., Hinduja, A. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Outcome of large hemispheric infarction in very elderly patients treated with medical management only (P4.289)
Conclusions:LHI in very elderly patients undergoing medical management only is associated with high mortality and nursing home placement for the survivors. No significant neurological improvement occurred during the hospitalization.Study Supported by: No funding was received for this study.Disclosure: Dr. Datar has nothing to disclose. Dr. Reynolds has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Datar, S., Reynolds, P. Tags: In-Hospital Stroke Care Source Type: research

Early Decompressive Hemicraniectomy for Malignant Middle Cerebral Artery Infarction: A single centre retrospective study (P4.290)
Conclusions:Early decompression craniectomy, especially in right MCA ischemic stroke is associated with better favorable functional outcome at 6 months.Disclosure: Dr. Bharatendu has nothing to disclose. Dr. Chong has nothing to disclose. Dr. Paliwal has nothing to disclose. Dr. Teoh has nothing to disclose. Dr. Yeo has nothing to disclose. Dr. Seet has nothing to disclose. Dr. Chan has nothing to disclose. Dr. YEO has nothing to disclose. Dr. LWIN has nothing to disclose. Dr. NING has nothing to disclose. Dr. SHARMA has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Bharatendu, C., Chong, Y. F. V., Paliwal, P., Teoh, H. L., Yeo, L., Seet, R., Chan, B., YEO, T. T., LWIN, S., NING, C., SHARMA, V. K. Tags: In-Hospital Stroke Care Source Type: research

Hemorrhagic transformation of ischemic strokes: risk factors and prognostic implications (P4.291)
Conclusions:IV thrombolytic therapy, cardioembolic stroke and prior warfarin use were independent predictors of HT. PH2 was associated with increased risk of poor outcome at around 90 days and mortality at 90 days and 5 years.Disclosure: Dr. Cheung has nothing to disclose. Dr. Chan has nothing to disclose. Dr. Lee has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Cheung, R., Chan, K. H., Lee, R. Tags: In-Hospital Stroke Care Source Type: research

Seizure Incidence in Ischemic Stroke Patients Treated with and without tPA: A Single Center Study (P4.292)
Conclusions:Treatment with tPA reduces the incidence of early onset seizures in stroke patients. Further studies would be needed to clarify the effect of tPA administration on the incidence of seizures after 24 hours.Disclosure: Dr. Vaidyanathan has nothing to disclose. Dr. Hawkins has nothing to disclose. Dr. Morris has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Vaidyanathan, V., Hawkins, A., Morris, H. Tags: In-Hospital Stroke Care Source Type: research