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An Unusual Presentation of Varicella Zoster Virus with Acute Cerebellitis and SIADH without a rash. (P2.315)
Conclusions:This report illustrates an unusual presentation of acute VZV cerebellitis and encephalitis, without a rash. To our understanding, this shows for the first time, severe acute onset neurological sequelae due to VZV.Disclosure: Dr. Lubomski has nothing to disclose. Dr. Markus has nothing to disclose. Dr. Brown has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Lubomski, M., Markus, R., Brown, L. Tags: HIV, HTLV-I, PML, Other Viral Infections, and CJD Source Type: research

Oculomotor Nerve Palsy after Herpes Zoster Opthalmicus: A Case Report and Review of Literature (P1.297)
Conclusions: HZO is manifestation of re-activation of herpes zoster with involvement of ophthalmic division of trigeminal nerve. CNIII palsy after HZO is rare, especially with associated pupillary defect. The long term prognosis is felt to be excellent with use of antiviral agents and steroids.Disclosure: Dr. Shaker has nothing to disclose. Dr. Rai has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Shaker, H., Rai, V. Tags: Herpes Virus Infections Source Type: research

Recurrent Strokes in Giant Cell Arteritis: Treatment Dilemma (P4.374)
Conclusions: Steroid resistant, aggressive GCA cases can lead to severe extracranial vasculopathy, dissection, recurrent strokes, and death. Thus we suggest that aggressive immunosuppression be considered early, particularly if complicated with arterial dissection and stroke. These patients may benefit from other potent immunosuppressant drugs such as disease modifying anti-rheumatic drugs, acyclovir, or monoclonal antibodies.Disclosure: Dr. Yadala has nothing to disclose. Dr. Kaur has nothing to disclose. Dr. Sahni has nothing to disclose. Dr. Lleva has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Yadala, V., Kaur, P., Sahni, R., Lleva, P. E. Tags: Cerebrovascular Case Reports Source Type: research

HSV-2 Encephalitis Presenting as Multifocal Ischemic Stroke (P4.375)
CONCLUSION A high index of suspicion needs to be maintained to diagnose infectious vasculitis. A history of immunosuppression and headache preceding cerebral infarction were important factors that ultimately led to the appropriate work up and diagnosis in this case. Lumbar puncture and prompt initiation of antiviral treatment is essential in stroke case of suspected CNS infection with HSV-2.Disclosure: Dr. Zhang has nothing to disclose. Dr. Sumida has nothing to disclose. Dr. Margolesky has nothing to disclose. Dr. Tornes has nothing to disclose. Dr. Ramos has nothing to disclose. Dr. Koch has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Zhang, F., Sumida, A., Margolesky, J., Tornes, L., Ramos, A., Koch, S. Tags: Cerebrovascular Case Reports Source Type: research

Cerebral Varicella Zoster Vasculopathy Sine Herpete: Atypical Ramsay-Hunt Syndrome Presentation in an Immunocompetent Patient (P6.258)
CONCLUSIONS:VZV CNS vasculopathy may present with atypical clinical and CSF characteristics. Patients with suspected CNS vasculitis without pathological confirmation should be tested for this treatable condition, regardless of their immune status.Disclosure: Dr. Gonzalez Otarula has nothing to disclose. Dr. Bruno has nothing to disclose. Dr. Pujol-Lereis has nothing to disclose. Dr. Ameriso has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Gonzalez Otarula, K., Bruno, V., Pujol-Lereis, V., Ameriso, S. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Cerebral microbleeding in varicella-zoster viral meningitis: An early sign of vasculopathy?
A 75-year-old man undergoing chemotherapy for prostate cancer for 3 months presented with headache after having blisters in his left ear canal and auricle. His body temperature at presentation was 38°C. Neurologic examination revealed nuchal stiffness and left peripheral facial palsy. We also noted leukocytopenia (2,000/µL) and elevated serum C-reactive protein (8.51 mg/dL). CSF analysis showed no erythrocytes, elevated leukocytes (640/µL; 3% monocytes, 97% neutrophils), an increased protein level (473 mg/dL), and slightly decreased glucose level (51 mg/dL, serum glucose 120 mg/dL). Brain MRI and magnetic r...
Source: Neurology - March 3, 2014 Category: Neurology Authors: Ohtomo, R., Shirota, Y., Iwata, A., Shimizu, J., Tsuji, S. Tags: MRI, Other cerebrovascular disease/ Stroke, Vasculitis, Viral infections CLINICAL/SCIENTIFIC NOTES Source Type: research

Herpes-Simplex Virus 2: A New Player in Cerebral Vasculitis (P03.259)
CONCLUSIONS: The spectrum of atypical CNS manifestations related to HSV is emerging. We report a case of cerebral vasculitis, which was masked by the initial presentation as thalamic hemorrhage and followed by an encephalitic syndrome and multifocal ischemic stroke. The work-up revealed HSV-2 as a new and treatable cause of infectious vasculitis.Supported by: JS is supported by a scientific fellowship from the European Federation of Neurological Societies.Disclosure: Dr. Sellner has nothing to disclose. Dr. Wunderlich has nothing to disclose. Dr. Förschler has nothing to disclose. Dr. Nadas has nothing to disclose. Dr...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Sellner, J., Wunderlich, S., Forschler, A., Nadas, K., Hemmer, B., Zepper, P. Tags: P03 Infections I Source Type: research