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Source: Nature Clinical Practice. Rheumatology.
Drug: Dexamethasone
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Cardiac manifestations of neonatal lupus erythematosus: guidelines to management, integrating clues from the bench and bedside
Nat Clin Pract Rheumatol. 2009 Mar;5(3):139-48. doi: 10.1038/ncprheum1018.ABSTRACTOne of the strongest clinical associations with autoantibodies against components of the SSA/Ro-SSB/La ribonucleoprotein complex is the development of congenital heart block in an offspring, an alarming prospect facing 2% of primigravid mothers with these reactivities. This risk is increased tenfold in women who have had a previous child with congenital heart block. Accumulated evidence suggests that anti-SSA/Ro and anti-SSB/La antibodies are necessary but insufficient for fetal disease. Basic and clinical research is heavily focused on ident...
Source: Nature Clinical Practice. Rheumatology. - March 3, 2009 Category: Rheumatology Authors: Jill P Buyon Robert M Clancy Deborah M Friedman Source Type: research
