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Specialty: Internal Medicine
Source: Annals of Internal Medicine
Drug: Activase

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Total 31 results found since Jan 2013.

In acute ischemic stroke, thrombectomy was not noninferior to alteplase + thrombectomy for 90-d functional independence
Ann Intern Med. 2022 Nov 1. doi: 10.7326/J22-0088. Online ahead of print.ABSTRACTFischer U, Kaesmacher J, Strbian D, et al. Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial. Lancet. 2022;400:104-15. 35810756.PMID:36315954 | DOI:10.7326/J22-0088
Source: Annals of Internal Medicine - October 31, 2022 Category: Internal Medicine Authors: Anthony A Donato Vaibhav Goswami Source Type: research

In acute ischemic stroke, early IV tenecteplase was noninferior to alteplase for excellent functional outcome
Ann Intern Med. 2022 Nov 1. doi: 10.7326/J22-0090. Online ahead of print.ABSTRACTMenon BK, Buck BH, Singh N, et al. Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised, controlled, non-inferiority trial. Lancet. 2022;400:161-9. 35779553.PMID:36315948 | DOI:10.7326/J22-0090
Source: Annals of Internal Medicine - October 31, 2022 Category: Internal Medicine Authors: Emma Ferguson Eddy Lang Source Type: research

In acute ischemic stroke, thrombectomy was not noninferior to alteplase + thrombectomy for 90-d functional independence
Ann Intern Med. 2022 Nov 1. doi: 10.7326/J22-0088. Online ahead of print.ABSTRACTFischer U, Kaesmacher J, Strbian D, et al. Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial. Lancet. 2022;400:104-15. 35810756.PMID:36315954 | DOI:10.7326/J22-0088
Source: Annals of Internal Medicine - October 31, 2022 Category: Internal Medicine Authors: Anthony A Donato Vaibhav Goswami Source Type: research

In acute ischemic stroke, early IV tenecteplase was noninferior to alteplase for excellent functional outcome
Ann Intern Med. 2022 Nov 1. doi: 10.7326/J22-0090. Online ahead of print.ABSTRACTMenon BK, Buck BH, Singh N, et al. Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised, controlled, non-inferiority trial. Lancet. 2022;400:161-9. 35779553.PMID:36315948 | DOI:10.7326/J22-0090
Source: Annals of Internal Medicine - October 31, 2022 Category: Internal Medicine Authors: Emma Ferguson Eddy Lang Source Type: research

In acute ischemic stroke, thrombectomy was not noninferior to alteplase + thrombectomy for 90-d functional independence
Ann Intern Med. 2022 Nov 1. doi: 10.7326/J22-0088. Online ahead of print.ABSTRACTFischer U, Kaesmacher J, Strbian D, et al. Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial. Lancet. 2022;400:104-15. 35810756.PMID:36315954 | DOI:10.7326/J22-0088
Source: Annals of Internal Medicine - October 31, 2022 Category: Internal Medicine Authors: Anthony A Donato Vaibhav Goswami Source Type: research

In acute ischemic stroke, early IV tenecteplase was noninferior to alteplase for excellent functional outcome
Ann Intern Med. 2022 Nov 1. doi: 10.7326/J22-0090. Online ahead of print.ABSTRACTMenon BK, Buck BH, Singh N, et al. Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised, controlled, non-inferiority trial. Lancet. 2022;400:161-9. 35779553.PMID:36315948 | DOI:10.7326/J22-0090
Source: Annals of Internal Medicine - October 31, 2022 Category: Internal Medicine Authors: Emma Ferguson Eddy Lang Source Type: research

In acute ischemic stroke, thrombectomy was not noninferior to alteplase + thrombectomy for 90-d functional independence
Ann Intern Med. 2022 Nov 1. doi: 10.7326/J22-0088. Online ahead of print.ABSTRACTFischer U, Kaesmacher J, Strbian D, et al. Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial. Lancet. 2022;400:104-15. 35810756.PMID:36315954 | DOI:10.7326/J22-0088
Source: Annals of Internal Medicine - October 31, 2022 Category: Internal Medicine Authors: Anthony A Donato Vaibhav Goswami Source Type: research

In acute ischemic stroke, early IV tenecteplase was noninferior to alteplase for excellent functional outcome
Ann Intern Med. 2022 Nov 1. doi: 10.7326/J22-0090. Online ahead of print.ABSTRACTMenon BK, Buck BH, Singh N, et al. Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised, controlled, non-inferiority trial. Lancet. 2022;400:161-9. 35779553.PMID:36315948 | DOI:10.7326/J22-0090
Source: Annals of Internal Medicine - October 31, 2022 Category: Internal Medicine Authors: Emma Ferguson Eddy Lang Source Type: research

In acute ischemic stroke, thrombectomy was not noninferior to alteplase + thrombectomy for 90-d functional independence
Ann Intern Med. 2022 Nov 1. doi: 10.7326/J22-0088. Online ahead of print.ABSTRACTFischer U, Kaesmacher J, Strbian D, et al. Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial. Lancet. 2022;400:104-15. 35810756.PMID:36315954 | DOI:10.7326/J22-0088
Source: Annals of Internal Medicine - October 31, 2022 Category: Internal Medicine Authors: Anthony A Donato Vaibhav Goswami Source Type: research

In acute ischemic stroke, early IV tenecteplase was noninferior to alteplase for excellent functional outcome
Ann Intern Med. 2022 Nov 1. doi: 10.7326/J22-0090. Online ahead of print.ABSTRACTMenon BK, Buck BH, Singh N, et al. Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised, controlled, non-inferiority trial. Lancet. 2022;400:161-9. 35779553.PMID:36315948 | DOI:10.7326/J22-0090
Source: Annals of Internal Medicine - October 31, 2022 Category: Internal Medicine Authors: Emma Ferguson Eddy Lang Source Type: research

In acute ischemic stroke, thrombectomy was not noninferior to alteplase + thrombectomy for 90-d functional independence
Ann Intern Med. 2022 Nov 1. doi: 10.7326/J22-0088. Online ahead of print.ABSTRACTFischer U, Kaesmacher J, Strbian D, et al. Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial. Lancet. 2022;400:104-15. 35810756.PMID:36315954 | DOI:10.7326/J22-0088
Source: Annals of Internal Medicine - October 31, 2022 Category: Internal Medicine Authors: Anthony A Donato Vaibhav Goswami Source Type: research

In acute ischemic stroke, early IV tenecteplase was noninferior to alteplase for excellent functional outcome
Ann Intern Med. 2022 Nov 1. doi: 10.7326/J22-0090. Online ahead of print.ABSTRACTMenon BK, Buck BH, Singh N, et al. Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised, controlled, non-inferiority trial. Lancet. 2022;400:161-9. 35779553.PMID:36315948 | DOI:10.7326/J22-0090
Source: Annals of Internal Medicine - October 31, 2022 Category: Internal Medicine Authors: Emma Ferguson Eddy Lang Source Type: research

In ischemic stroke, IV alteplase within 3 h of onset improves functional outcome vs. control
Ann Intern Med. 2022 Sep 6. doi: 10.7326/J22-0069. Online ahead of print.ABSTRACTMun KT, Bonomo JB, Liebeskind DS, et al. Fragility index meta-analysis of randomized controlled trials shows highly robust evidential strength for benefit of < 3 hour intravenous alteplase. Stroke. 2022;53:2069-74. 35543129.PMID:36063553 | DOI:10.7326/J22-0069
Source: Annals of Internal Medicine - September 5, 2022 Category: Internal Medicine Authors: Barnet Eskin Source Type: research

In acute ischemic stroke, EVT alone vs. IV alteplase plus EVT did not differ for functional outcome at 90 d
Ann Intern Med. 2022 Apr 5. doi: 10.7326/J22-0016. Online ahead of print.ABSTRACTLeCouffe NE, Kappelhof M, Treurniet KM, et al. A randomized trial of intravenous alteplase before endovascular treatment for stroke. N Engl J Med. 2021;385:1833-44. 34758251.PMID:35377718 | DOI:10.7326/J22-0016
Source: Annals of Internal Medicine - April 4, 2022 Category: Internal Medicine Authors: Barnet Eskin Source Type: research